Current therapies for advanced colorectal cancer

ONCOLOGY

Volumn 19, Issue 5, 2005, Pages 589-595

  Aggarwal, Sandhya ^a   Edward, C H U ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DEOXYCYTIDINE; DRUG DERIVATIVE; MONOCLONAL ANTIBODY; PLATINUM COMPLEX;

ACNE; ADJUVANT CHEMOTHERAPY; ADVANCED CANCER; ALOPECIA; ASTHENIA; BONE MARROW SUPPRESSION; CANCER COMBINATION CHEMOTHERAPY; CANCER GROWTH; CANCER SURVIVAL; CLINICAL TRIAL; COLORECTAL CANCER; CONTROLLED CLINICAL TRIAL; DEHYDRATION; DIARRHEA; DIGESTIVE SYSTEM PERFORATION; FATIGUE; FEBRILE NEUTROPENIA; GASTROINTESTINAL TOXICITY; HUMAN; HYPERTENSION; LARYNX SPASM; LETHARGY; MALAISE; META ANALYSIS; METASTASIS; NAUSEA; NEPHROTOXICITY; NEUTROPENIA; PARESTHESIA; PHARYNX DISEASE; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL; RASH; REVIEW; SENSORY NEUROPATHY; SIGNAL TRANSDUCTION; STOMATITIS; SYSTEMATIC REVIEW; THROMBOCYTOPENIA; TREATMENT OUTCOME; TREATMENT RESPONSE; VOMITING; COLORECTAL TUMOR;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CAMPTOTHECIN; COLORECTAL NEOPLASMS; DEOXYCYTIDINE; FLUOROURACIL; HUMANS; ORGANOPLATINUM COMPOUNDS;

EID: 22144478699     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (37)

1. Jemal A, Murray T, Ward E, et al: Cancer statistics, 2005. CA Cancer J Clin 55:10-30, 2005.
2. Midgley R, Kerr D: Colorectal cancer. Lancet 353:391-399, 1999.
3. Meyerhardt JA, Mayer RJ: Systemic therapy for colorectal cancer. N Engl J Med 352:476-487, 2005.
4. Hoff P, Pazdur R: Progress in the development of novel treatments for colorectal cancer. Oncology 18:705-708, 2004.
5. The Meta-Analysis Group in Cancer: Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol 16:301-308, 1998.
6. The Meta-Analysis Group in Cancer: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: An updated meta-analysis. J Clin Oncol 22:3766-3775, 2004.
7. Chu E, Eng C, Abbruzzese J, et al: Efficacy and safety of capecitabine for colorectal cancer. Am J Oncol Rev 2(suppl 3):1-28, 2003.
8. Hoff PM, Ansari R, Batist G, et al: Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-time treatment in 605 patients with metastatic colorectal cancer: Results of a randomized phase III study. J Clin Oncol 19:2282-2292, 2001.
9. van Cutsem E, Twelves C, Cassidy J, et al: Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study. J Clin Oncol 19:4097-4106, 2001.
10. Twelves C, for the Xeloda Colorectal Cancer Group: Capecitabine as first-line treatment in colorectal cancer: Pooled data from two large, phase III trials. Eur J Cancer 38(suppl 2):S15-S20, 2002.
11. Vanhoefer U, Harstrick A, Achterrath W, et al: Irinotecan in the treatment of colorectal cancer: Clinical overview. J Clin Oncol 19:1501-1518, 2001.
12. Douillard JY, Cunningham D, Roth AD, et al: Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial. Lancet 355:1041-1047, 2000.
13. Saltz LB, Cox JV, Blanke C, et al: Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. N Engl J Med 343:905-914, 2000.
14. Kohne C-H, Van Cutsem E, Wils JA, et al: Irinotecan improves the activity of the AIO regimen in metastastic colorectal cancer: Results of EORTC GI Group study 40986 (abstract 1018). Proc Am Soc Clin Oncol 22:254, 2003.
15. Patt YZ, Lin E, LeibmannJ, et al:Capecitabine (X) plus irinotecan (XELIRI) for first-line treatment for metastatic colorectal cancer (MCRC): Final safety findings from a phase II trial (abstract 3602). Proc Am Soc Clin Oncol 23:271, 2004.
16. Bajetta, E, Bartolomeo, M, Mariani, L, et al: Randomized multicenter phase II trial of two different schedules of irinotecan combined with capecitabine as first line treatment in metastatic colorectal carcinoma. Cancer 100:279-287, 2004.
17. Grothey A, Goldberg RM: A review of oxaliplatin and its clinical use in colorectal cancer. Expert Opin Pharmacother 5:2159-2170, 2004.
18. de Gramont A, Figer A, Seymour M, et al: Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 18:2938-2947, 2000.
19. Goldberg RM, Sargent DJ, Morton RF, et al: A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 22:23-30, 2004.
20. Maindrault-Goebel F, Louvet C, André T, et al: Oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX6). Eur J Cancer 35:1338-1342, 1999.
21. Tournigand,C, Andre, T, Achille,E, et al: FOLFIRI followed by FOLFOX 6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study. J Clin Oncol 22:229-237, 2004.
22. Maindrault-Goebel F, de Gramont A, Louvet C, et al: High-dose intensity oxaliplatin added to the simplified bimonthly leucovorin and 5-fluorouracil regimen as second-line therapy for metastatic colorectal cancer (FOLFOX 7). Eur J Cancer 37:1000-1005, 2001.
23. De Gramont A, Cervantes A, Andre T, et al: OPTIMOX study: FOLFOX 7/LV5FU2 compared to FOLFOX 4 in patients with advanced colorectal cancer (abstract 3525). Proc Am Soc Clin Oncol 23:251, 2004.
24. Scheithauer W, Kornek GV, Raderer M, et al: Randomized multicenter phase II trial of two different schedules of capecitabine plus oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 21:1307-1312, 2003.
25. Cassidy J, Tabernero J, Twelves C, et al: XELOX (capecitabine plus oxaliplatin): Active first-line therapy for patients with metastatic colorectal cancer. J Clin Oncol 22:2084-2091, 2004.
26. Mendolsohn J, Baselga J: Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 21:2787-2799, 2003.
27. Saltz L, Rubin M, Hochster H, et al: Cetuximab (IMC-C225) plus irinotecan is active in CPT-11 refractory colorectal cancer that expresses epidermal growth factor receptor (EGFR) (abstract 7). Proc Am Soc Clin Oncol 20:3a, 2001.
28. Saltz LB, Meropol NJ, Loehrer Jr PJ, et al: Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 22:1201-1208, 2004.
29. Cunningham D, Humblet Y, Siena S, et al: A randomized comparison of cetuximab monotherapy and cetuximab combination with irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351:337-345, 2004.
30. Lenz HJ, Mayer RJ, Gold PJ, et al: Activity of cetuximab in patients with colorectal cancer refractory to both irinotecan and oxaliplatin (abstract 3510). Proc Am Soc Clin Oncol 23:248, 2004.
31. Folprecht G, Lutz M, Schoeffski P, et al: Cetuximab/irinotecan/high-dose 5-fluorouracil/leucovorin (HD-5-FU/LV) in the first line therapy of metastatic colorectal cancer (abstract 283). ASCO Gastrointestinal Cancers Symposium 2004.
32. Tabemero JM, Van Cutsem E, Sastre J, et al: An international phase II study of cetuximab in combination with oxaliplatin/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFOX4) in the first line treatment of patients with metastatic colorectal cancer expressing epidermal growth factor receptor (EGFR). Preliminary results (abstract 3512). Proc Am Soc Clin Oncol 23:248, 2004.
33. Collins TS, Hurwitz HL: Targeting vascular endothelial growth factor and angiogenesis for the treatment of colorectal cancer. Semin Oncol 32:61-68, 2005.
34. Hurwitz H, Fehrenbacher L, Novotny W, et al: Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350:2335-2342, 2004.
35. Kabbinavar F, Schultz J, McCleod M, et al: Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) to prolong progression-free survival in first-line colorectal cancer (CRC) patients who are not suitable candidates for first-line CPT-11 (abstract 3516). Proc Am Soc Clin Oncol 23:249, 2004.
36. Benson AB, Catalano PJ, Meropol NJ, et al: Bevacizumab (anti-VEGF) plus FOLFOX4 in previously treated advanced colorectal cancer (advCRC): An interim toxicity analysis of the Eastern Cooperative Oncology Group (ECOG) study E3200 (abstract 975). Proc Am Soc Clin Oncol 22:243, 2003.
37. Mitchell EP, Alberts SR, Schwartz MA, et al: High-dose bevacizumab in combination with FOLFOX4 improves survival in patients with previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group (ECOG) study E3200 (abstract 169a). ASCO Gastrointestinal Cancers Symposium 2005.