메뉴 건너뛰기




Volumn 19, Issue 5, 2001, Pages 1501-1518

Irinotecan in the treatment of colorectal cancer: Clinical overview

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN DERIVATIVE; CAPECITABINE; DNA TOPOISOMERASE INHIBITOR; FLUOROURACIL; FOLINIC ACID; GRANULOCYTE COLONY STIMULATING FACTOR; IRINOTECAN; MITOMYCIN C; OXALIPLATIN; RALTITREXED; SEROTONIN 3 ANTAGONIST; THYMIDYLATE SYNTHASE INHIBITOR; UFT;

EID: 0035281522     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2001.19.5.1501     Document Type: Review
Times cited : (291)

References (197)
  • 1
    • 0030931974 scopus 로고    scopus 로고
    • A comprehensive review of 5-fluorouracil and leucovorin in patients with metastatic colorectal carcinoma
    • (1997) Cancer , vol.80 , pp. 1179-1187
    • Machover, D.1
  • 3
    • 0344109583 scopus 로고    scopus 로고
    • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
    • (1998) J Clin Oncol , vol.16 , pp. 301-308
  • 6
    • 0029960812 scopus 로고    scopus 로고
    • Eukaryotic DNA topoisomerase 1: Genome gatekeeper and its intruders, camptothecins
    • (1996) Semin Oncol , vol.23 , Issue.SUPPL. 3 , pp. 3-10
    • Pommier, Y.1
  • 7
    • 0029841505 scopus 로고    scopus 로고
    • Irinotecan: A review of its pharmacological properties and clinical efficacy in the management of advanced colorectal cancer
    • (1996) Drugs , vol.52 , pp. 606-623
    • Wisemann, L.R.1    Markham, A.2
  • 13
    • 0003204021 scopus 로고    scopus 로고
    • A randomized phase II trial assessing irinotecan (IRI) and 5FU/folinic acid (LV), "Mayo regimen", in first line palliative chemotherapy patients with metastatic colorectal cancer
    • abstr
    • (1999) Eur J Cancer , vol.35 , Issue.SUPPL. 4
    • Pozzo, C.1    Pyrhönen, S.2    Bodrogi, I.3
  • 14
    • 0031014627 scopus 로고    scopus 로고
    • Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naïve patients and patients pretreated with fluorouracil-based chemotherapy
    • (1997) J Clin Oncol , vol.15 , pp. 251-260
    • Rougier, P.1    Bugat, R.2    Douillard, J.Y.3
  • 24
  • 40
  • 43
    • 0023924786 scopus 로고
    • Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • (1988) Cancer Res , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 44
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • (1989) Cancer Res , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 46
    • 0027139317 scopus 로고
    • Interaction between replication forks and topoisomerase I-DNA cleavable complexes: Studies in a cell-free SV 40 DNA replication system
    • (1993) Cancer Res , vol.53 , pp. 5908-5914
    • Tsao, Y.P.1    Russo, A.2    Nyamuswa, G.3
  • 48
    • 0023462741 scopus 로고
    • Microinjection of anti-topoisomerase I immunoglobulin G into nuclei of Chironomus tentans salivary gland cells leads to blockage of transcription elongation
    • (1987) Mol Cell Biol , vol.7 , pp. 4308-4316
    • Egyházi, E.1    Durban, E.2
  • 51
    • 0027324850 scopus 로고
    • Therapeutic efficacy of the topoisomerase l inhibitor 7-ethyl-10-(4-[1-piperidino]l-piperidino]-carbonyloxy-camptothecin against human tumor xenografts: Lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor 9-dimethylaminomethyl- 10-hydroxycamptothecin
    • (1993) Cancer Res , vol.53 , pp. 2823-2829
    • Houghton, P.J.1    Cheshire, P.J.2    Hallman, J.C.3
  • 58
    • 0028006314 scopus 로고
    • Elevation of topoisomerase I mRNA, protein, and catalytic activity in human tumors: Demonstration of tumor-type specificity and implications for cancer chemotherapy
    • (1994) Cancer Res , vol.54 , pp. 539-546
    • Husain, I.1    Mohler, J.L.2    Seigerl, H.F.3
  • 62
    • 0026326003 scopus 로고
    • P-glycoprotein expression and DNA topoisomerase I and II activity in benign tumors of the ovary and in malignant tumors of the ovary, before and after platinum/cyclophosphamide chemotherapy
    • (1991) Cancer Res , vol.51 , pp. 5915-5920
    • Van der Zee, A.G.J.1    Hollema, H.2    De Jong, S.3
  • 64
    • 0029029436 scopus 로고
    • Topoisomerase I-related parameters and camptothecin activity in the colon carcinoma cell lines from the National Cancer Institute anticancer screen
    • (1995) Cancer Res , vol.55 , pp. 2116-2121
    • Goldwasser, F.1    Bae, I.2    Valenti, M.3
  • 66
    • 0032617046 scopus 로고    scopus 로고
    • Dimerization of mitochondrial Bax is associated with increased drug response in Bax-transfected A 253 cells
    • (1999) Oncol Res , vol.11 , pp. 91-99
    • Guo, B.1    Yin, M.B.2    Toth, K.3
  • 67
    • 0345062128 scopus 로고    scopus 로고
    • Involvement of cyclin DI-CDK5 overexpression and MCM3 cleavage in bax-associated spontaneous apoptosis and differentiation in an A253 human head and neck carcinoma xenograft model
    • (1999) Int J Cancer , vol.83 , pp. 341-348
    • Yin, M.B.1    Toth, K.2    Cao, S.3
  • 68
    • 0033982752 scopus 로고    scopus 로고
    • Overexpression of Bax enhances antitumor activity of chemotherapeutic agents in human head and neck squamous cell carcinoma
    • (2000) Clin Cancer Res , vol.6 , pp. 718-724
    • Guo, B.1    Can, S.2    Toth, K.3
  • 74
    • 0025084410 scopus 로고
    • Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human nonsmall cell lung cancer: Characterization and mechanism of resistance
    • (1990) Cancer Res , vol.50 , pp. 5919-5924
    • Kanzawa, F.1    Sugimoto, Y.2    Minato, K.3
  • 81
    • 0028228297 scopus 로고
    • Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase 11 in a melphalan-resistant rhabdomyosarcoma xenograft that is crossresistant to nitrosoureas and topotecan
    • (1994) Cancer Res , vol.54 , pp. 3487-3493
    • Friedman, H.S.1    Dolan, M.E.2    Kaufmann, S.H.3
  • 85
    • 0005691998 scopus 로고    scopus 로고
    • Antitumor efficacy of irinotecan (CPT-11) and topotecan in nude mice bearing tumor xenografts that express the multidrug resistance protein (MRP)
    • abstr
    • (1999) Onkologie , vol.22 , Issue.SUPPL. 1 , pp. 219
    • Hapke, G.1    Vanhoefer, U.2    Harstrick, A.3
  • 89
    • 0029091756 scopus 로고
    • Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations
    • (1995) Cancer Res , vol.55 , pp. 4004-4009
    • Yang, C.H.J.1    Horton, J.K.2    Cowan, K.H.3
  • 91
    • 0033429542 scopus 로고    scopus 로고
    • Camptothecin resistance: Role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
    • (1999) Cancer Res , vol.59 , pp. 5938-5946
    • Brangi, M.1    Litman, T.2    Ciotti, M.3
  • 94
    • 0031940425 scopus 로고    scopus 로고
    • High-dose topotecan with granulocyte-colony stimulating factor in fluoropyrimidine-refractory colorectal cancer: A phase II and pharmacodynamic study
    • (1998) Ann Oncol , vol.9 , pp. 173-180
    • Rowinsky, E.K.1    Baker, S.D.2    Burks, K.3
  • 108
    • 0033002906 scopus 로고    scopus 로고
    • Combination of oxaliplatin plus irinotecan in patients with gastrointestinal tumors: Results of two independent phase I studies with pharmacokinetics
    • (1999) J Clin Oncol , vol.17 , pp. 1751-1759
    • Wasserman, E.1    Cuvier, E.2    Lokiec, F.3
  • 111
    • 0029741368 scopus 로고    scopus 로고
    • Involvement of β-glucuronidase in intestinal microflora in the intestinal toxicity of the antitumor camptothecin derivative irinotecan hydrochloride (CPT-11) in rats
    • (1996) Cancer Res , vol.56 , pp. 3752-3757
    • Takasuna, K.1    Hagiwara, T.2    Hirohashi, M.3
  • 113
  • 117
  • 123
    • 0028158012 scopus 로고
    • Phase I and pharmacological study of the novel topoisomerase 1 inhibitor 7-ethyl-10-[4-(l-piperidino)piperidino] carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks
    • (1994) Cancer Res , vol.54 , pp. 427-436
    • Rowinsky, E.K.1    Grochow, L.B.2    Ettinger, D.S.3
  • 128
    • 0028840093 scopus 로고
    • Phase I and pharmacokinetic study of irinotecan (CPT-11) administered daily for three consecutive days every three weeks in patients with advanced solid tumors
    • (1995) Ann Oncol , vol.6 , pp. 133-140
    • Catimel, G.1    Chabot, G.G.2    Guastalla, J.P.3
  • 134
    • 0345425754 scopus 로고    scopus 로고
    • Concurrent irinotecan and 5-fluorouracil plus levo-folinic acid given every other week in the first-line management of advanced colorectal carcinoma: A phase I study of the Southern Italy Cooperative Oncology Group
    • (1999) Ann Oncol , vol.10 , pp. 915-921
    • Comella, P.1    Casaretti, R.2    De Vita, F.3
  • 135
    • 0032833697 scopus 로고    scopus 로고
    • Irinotecan combined with bolus fluorouracil, continuous infusion fluorouracil, and high-dose leucovorin every two weeks (LV5FU2 regimen): A clinical dosefinding and pharmacokinetic study in patients with pretreated metastatic colorectal cancer
    • (1999) J Clin Oncol , vol.17 , pp. 2901-2908
    • Ducreux, M.1    Ychou, M.2    Seitz, J.F.3
  • 136
    • 0001548604 scopus 로고    scopus 로고
    • Escalating dose irinotecan (CPT-11) immediately prior or after 5-fluorouracil (5-FU) 48 hours infusion + leucovorin (LV): Pharmacokinetic and pharmacodynamic interactions in chemotherapy-naïve metastatic colorectal cancer patients
    • abstr 924
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Falcone, A.1    Danesi, R.2    Allegrini, G.3
  • 141
    • 0013692353 scopus 로고    scopus 로고
    • Phase I dose finding study of irinotecan (CPT-11) over a short IV infusion combined with a fixed dose of 5-fluorouracil (5-FU) over a protracted IV infusion in patients with advanced solid tumors
    • abstr 775
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Sastre, H.1    Paz-Ares, L.2    Diaz-Rubio, E.3
  • 142
    • 0032977698 scopus 로고    scopus 로고
    • Phase I study of a weekly schedule of irinotecan, high-dose leucovorin, and infusional fluorouracil as first-line chemotherapy in patients with advanced colorectal cancer
    • (1999) J Clin Oncol , vol.17 , pp. 907-913
    • Vanhoefer, U.1    Harstrick, A.2    Köhne, C.H.3
  • 144
    • 0000271237 scopus 로고    scopus 로고
    • Irinotecan in combination with leucovorin and 5-fluorouracil 48 hours continuous infusion: A phase I study with pharmacokinetic, DNA damage and topoisomerase I/DNA complexes evaluation in chemotherapy naïve metastatic colorectal cancer patients
    • abstr 1117
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Falcone, A.1    Allegrini, G.2    Masi, G.3
  • 151
  • 154
    • 0005692485 scopus 로고    scopus 로고
    • Identification of a new metabolite of CPT-11 (irinotecan): Biosynthesis and activation to SN-38 by human hepatic microsomes
    • abstr
    • (1998) Ann Oncol , vol.9 , Issue.SUPPL. 2 , pp. 58
    • Haaz, M.C.1    Dodds, H.M.2    Riou, J.F.3
  • 156
    • 0028670840 scopus 로고
    • Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients
    • (1994) Cancer Res , vol.54 , pp. 6330-6333
    • Rivory, L.P.1    Chatelut, E.2    Canal, P.3
  • 162
    • 0005757048 scopus 로고    scopus 로고
    • Phase II study of irinotecan (CPT-11) in the treatment of patients with advanced colorectal cancer resistant to 5-fluorouracil (5-FU) based chemotherapy: The experience of TTD Spanish Cooperative Group
    • abstr 1071
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Anton, A.1    Aranda, E.2    Carrato, A.3
  • 172
    • 0032585232 scopus 로고    scopus 로고
    • Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
    • (1998) Lancet , vol.352 , pp. 1413-1418
    • Cunningham, D.1    Pyrhönen, S.2    James, R.D.3
  • 173
    • 0032585197 scopus 로고    scopus 로고
    • Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
    • (1998) Lancet , vol.352 , pp. 1407-1412
    • Rougier, P.1    Van Cutsem, E.2    Bajetta, E.3
  • 174
    • 0000236584 scopus 로고    scopus 로고
    • Two different schedules of irinotecan (CPT-11) administration in patients with advanced colorectal carcinoma relapsing after a 5-fluorouracil (5-FU)-leucovorin (L) combination chemotherapy. Preliminary results of a randomized study
    • abstr 998
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Tsavaris, N.1    Ziras, N.2    Kosmas, C.3
  • 178
    • 0033913981 scopus 로고    scopus 로고
    • Prognostic factors for tumour response, progression-free survival and toxicity in metastatic colorectal cancer patients given irinotecan (CPT-11) as second-line chemotherapy after 5-FU failure
    • (2000) Br J Cancer , vol.83 , pp. 431-437
    • Freyer, G.1    Rougier, P.2    Bugat, R.3
  • 181
  • 183
    • 0033047747 scopus 로고    scopus 로고
    • Combined irinotecan and oxaliplatin plus granulocyte colony-stimulating factor in patients with advanced fluoropyrimidine/leucovorin-pretreated colorectal cancer
    • (1999) J Clin Oncol , vol.17 , pp. 902-906
    • Scheithauer, W.1    Kornek, G.V.2    Raderer, M.3
  • 184
    • 0005758056 scopus 로고    scopus 로고
    • Randomized phase II study of irinotecan plus mitomycin (MMC) versus oxaliplatin plus MMC in patients with advanced fluoropyrimidine/leucovorinpretreated colorectal cancer (ACC)
    • abstr
    • (1999) Onkologie , vol.22 , Issue.SUPPL. 1 , pp. 78
    • Scheithauer, W.1    Kornek, G.V.2    Brugger, S.3
  • 186
    • 7844220589 scopus 로고    scopus 로고
    • A phase II study of irinotecan alternated with five days bolus of 5-fluorouracil and leucovorin in first-line chemotherapy of metastatic colorectal cancer
    • (1998) Ann Oncol , vol.9 , pp. 1199-1204
    • Van Cutsem, E.1    Pozzo, C.2    Starkhammar, H.3
  • 188
    • 0005692004 scopus 로고    scopus 로고
    • Decrease of severe toxicities by reducing the 5-FU-dosage in the combination therapy with CPT-11/5-FU/FA weekly in patients with advanced colorectal cancer
    • abstr
    • (1999) Onkologie , vol.22 , Issue.SUPPL. 1 , pp. 84
    • Lipp, R.1    Hegewichs-Becker, S.2    Gothert, J.3
  • 189
    • 0005661407 scopus 로고    scopus 로고
    • Folinic acid (FA) and 5-fluorouracil/FU) alone or with irinotecan (CPT-11) for advanced colorectal cancer: Preliminary results of a randomized phase II trial
    • abstr
    • (1999) Eur J Cancer , vol.35 , Issue.SUPPL. 4 , pp. 220
    • Maiello, E.1    Giuliani, F.2    Gebbia, V.3
  • 191
    • 0034712536 scopus 로고    scopus 로고
    • Irinotecan combined with fluorouracil compared with fluorouracil alone as firstline treatment for metastatic colorectal cancer: A multicentre randomised trial
    • (2000) Lancet , vol.355 , pp. 1041-1047
    • Douillard, J.Y.1    Cunningham, D.2    Roth, A.D.3
  • 194
    • 0003353972 scopus 로고    scopus 로고
    • Combined analysis of two phase III randomized trials comparing irinotecan (C), fluorouracil (F), leucovorin (L) vs F alone as first-line therapy of previously untreated metastatic colorectal cancer (MCRC)
    • abstr 938
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • Saltz, L.B.1    Douillard, J.2    Pirotta, N.3
  • 196
    • 0033989203 scopus 로고    scopus 로고
    • Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracilleucovorin as first-line treatment of metastatic colorectal cancer
    • (2000) J Clin Oncol , vol.18 , pp. 136-147
    • Giacchetti, S.1    Perpoint, B.2    Zidani, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.