Ribozyme targeting HPV16 E6E7 transcripts in cervical cancer cells suppresses cell growth and sensitizes cells to chemotherapy and radiotherapy

Cancer Biology and Therapy

Volumn 3, Issue 11, 2004, Pages 1129-1134

  Zheng, Yanfang ^a   Zhang, Jiren ^b   Rao, Zhiguo ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Cervical cancer; Chemotherapy; Gene therapy; Human papillomavirus; Radiotherapy; Ribozyme

Indexed keywords

CISPLATIN; HAMMERHEAD RIBOZYME; HAMMERHEAD RIBOZYME RZ170; PROTEIN BCL 2; PROTEIN E6; PROTEIN E7; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; MESSENGER RNA; ONCOPROTEIN; PROTEIN C MYB; PROTEIN TYROSINE KINASE; REPRESSOR PROTEIN; RIBOZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CHEMOTHERAPY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; ONCOGENE C MYC; PROTEIN EXPRESSION; UTERINE CERVIX CANCER; VIRUS EXPRESSION; VIRUS TRANSCRIPTION; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CELL PROLIFERATION; DRUG ANTAGONISM; DRUG RESISTANCE; METABOLISM; NUDE MOUSE; PATHOLOGY; RADIATION DOSE; UTERINE CERVIX TUMOR; X RAY;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL PROLIFERATION; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; ONCOGENE PROTEINS, VIRAL; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYB; RADIOTHERAPY DOSAGE; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; RNA, CATALYTIC; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS; X-RAYS;

EID: 22144475879     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.3.11.1215     Document Type: Article

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