Effects on tumor cells of ribozymes that cleave the RNA transcripts of human papillomavirus type 18

Cancer Gene Therapy

Volumn 3, Issue 1, 1996, Pages 18-23

  Chen, Zhuo ^a   Kamath, Poornima ^a   Zhang, Su ^a   St John, Lisa ^a   Adler Storthz, Karen ^a   Shillitoe, Edward J ^b  

^a UNIVERSITY OF TEXAS DENTAL BRANCH AT HOUSTON   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Antisense; Human papillomavirus; Ribozyme

Indexed keywords

ANDROSTANOLONE; ANTIBIOTIC G 418; COMPLEMENTARY RNA; GENTAMICIN; MESSENGER RNA; PRIMER DNA; PROTEIN P53; RIBOZYME; VIRUS RNA;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL DIVISION; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HELA CELL; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PAPILLOMA VIRUS;

BASE SEQUENCE; CELL ADHESION; CELL DIVISION; DIHYDROTESTOSTERONE; DNA PRIMERS; GENE EXPRESSION; GENE THERAPY; GENTAMICINS; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PAPILLOMAVIRIDAE; RNA, ANTISENSE; RNA, CATALYTIC; RNA, MESSENGER; RNA, VIRAL; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0029685259     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Shillitoe EJ, Lapeyre JN, Adler-Storthz K. Gene therapyits potential in the management of oral cancer. Oral Oncol Eur J Cancer. 1994;30B:143-154.
2. Shillitoe EJ, Kamath P, Chen G. Papillomaviruses as targets for cancer gene therapy. Cancer Gene Ther. 1994; 1:193-204.
3. He YK, Lu CD, Qi GR. In vitro cleavage of HPV16 E6 and E7 RNA fragments by synthetic ribozymes and transcribed ribozymes from RNA-trimming plasmids. Fed Eur Biochem Soc. 1993;322:21-24.
4. Lu D, Chatterjee S, Brar D, Wong KK. Ribozyme-mediated in vitro cleavage of transcripts arising from the major transforming genes of human papillomavirus type 16. Cancer Gen Ther. 1994; 1:267-277.