Stereoselective synthesis of β-anomeric 4′-thiaspirocyclic ribonucleosides carrying the full complement of RNA-level hydroxyl substitution

Journal of Organic Chemistry

Volumn 70, Issue 14, 2005, Pages 5655-5664

  Paquette, Leo A ^a   Dong, Shuzhi ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; SUBSTITUTION REACTIONS; SUBSTRATES; SYNTHESIS (CHEMICAL);

NUCLEOBASES; PIVOTAL SULFOXIDES; PYRIMIDINE; STEREOISOMERIC SERIES; STEREOSELECTIVE SYNTHESIS;

HYDROXYLATION;

2,4 DIMETHOXYBENZOYLOXY DERIVATIVE; 4' THIASPIROCYCLIC RIBONUCLEOSIDE; ANOMER; FUNCTIONAL GROUP; HYDROXYL GROUP; NUCLEIC ACID BASE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RIBONUCLEOSIDE DERIVATIVE; RNA; SPIRO COMPOUND; SULFOXIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; CHEMOREACTIVITY; CONFORMATION; ELIMINATION REACTION; ISOMER; PUMMERER REACTION; STEREOCHEMISTRY; STEREOISOMERISM; SUBSTITUTION REACTION; SYNTHESIS;

CYCLIZATION; MODELS, CHEMICAL; RIBONUCLEOSIDES; RNA; SPIRO COMPOUNDS; STEREOISOMERISM; SULFOXIDES;

EID: 22144464476     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0506985     Document Type: Article

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