Novel stereoselective entry to 2′-β-carbon-substituted 2′-deoxy-4′-thionucleosides from 4-thiofuranoid glycals

Organic Letters

Volumn 6, Issue 16, 2004, Pages 2645-2648

  Haraguchi, Kazuhiro ^a   Shiina, Noriaki ^a   Yoshimura, Yuichi ^a   Shimada, Hisashi ^a   Hashimoto, Kyoko ^a   Tanaka, Hiromichi ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; FURAN DERIVATIVE; NUCLEOSIDE;

ARTICLE; BIRCH REDUCTION; CHEMICAL REACTION; GLYCOSIDATION; LITHIATION; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS;

MOLECULAR STRUCTURE; SILOXANES; STEREOISOMERISM; THIONUCLEOSIDES; THIOPHENES;

EID: 4344692335     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol040035u     Document Type: Article

References (13)

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12. We expected that the use of 3,5-O-(di-tert-butylsilylene)-protected 4-thiofuranoid glycal 7 would give better stereoselectivity in the glycosidation step. However, the Cl-chlorinated product derived from 7 was found to be unstable.
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