Linking Kaposi virus to cancer-associated cytokines

Trends in Molecular Medicine

Volumn 11, Issue 7, 2005, Pages 309-312

  Wang, Hsei Wei ^a   Boshoff, Chris ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; KAPOSIN B; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

CARCINOGENESIS; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; ENZYME ACTIVATION; HERPES VIRUS; HUMAN; KAPOSI SARCOMA; KAPOSI SARCOMA HERPESVIRUS; NONHUMAN; ONCOVIRINAE; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SHORT SURVEY; SIGNAL TRANSDUCTION; VIRUS INFECTION; VIRUS INFECTIVITY;

CYTOKINES; HERPESVIRUS 8, HUMAN; HUMANS; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; NEOPLASMS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, MESSENGER; UP-REGULATION; VIRAL PROTEINS;

HERPESVIRIDAE;

EID: 22144464024     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmed.2005.06.002     Document Type: Short Survey

References (19)

1. A. Kotlyarov MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis Nat. Cell Biol. 1 1999 94 97
2. A. Neininger MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels J. Biol. Chem. 277 2002 3065 3068
3. C. McCormick, and D. Ganem The kaposin B protein of KSHV activates the p38/MK2 pathway and stabilizes cytokine mRNAs Science 307 2005 739 741
4. C. Boshoff, and R. Weiss AIDS-related malignancies Nat. Rev. Cancer 2 2002 373 382
5. B. Ensoli AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects Science 243 1989 223 226
6. N. Dupin Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma Proc. Natl. Acad. Sci. U. S. A. 96 1999 4546 4551
7. E. Oksenhendler High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients Blood 96 2000 2069 2073
8. H.G. Drexler Constitutive cytokine production by primary effusion (body cavity-based) lymphoma-derived cell lines Leukemia 13 1999 634 640
9. D. Di Bartolo, and E. Cesarman Uncovering the complexities of Kaposi's sarcoma through genome-wide expression analysis Genome Biol. 5 2004 247 248
10. H.W. Wang Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma Nat. Genet. 36 2004 687 693
11. INK4A-induced cell cycle arrest J. Biol. Chem. 280 2005 3862 3874
12. Montaner, S. et al. (2004) The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia. Blood 104, 2903-2911. Epub 2004 Jul 2901
13. L. Liu The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the IκB kinase complex J. Biol. Chem. 277 2002 13745 13751
14. J. An Kaposi's sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: the role of the NF-κB and JNK/AP1 pathways Oncogene 22 2003 3371 3385
15. R. Sadler A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi's sarcoma-associated herpesvirus J. Virol. 73 1999 5722 5730
16. G. Stoecklin MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay EMBO J. 23 2004 1313 1324
17. M.A. Frevel p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts Mol. Cell. Biol. 23 2003 425 436
18. B. Glaunsinger, and D. Ganem Highly selective escape from KSHV-mediated host mRNA shutoff and its implications for viral pathogenesis J. Exp. Med. 200 2004 391 398
19. A. Kotlyarov Distinct cellular functions of MK2 Mol. Cell. Biol. 22 2002 4827 4835