Uncovering the complexities of Kaposi's sarcoma through genome-wide expression analysis

Genome Biology

Volumn 5, Issue 11, 2004, Pages

  Di Bartolo, Daniel ^a   Cesarman, Ethel ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; LATENCY ASSOCIATED NUCLEAR ANTIGEN; MEMBRANE PROTEIN; STEM CELL FACTOR; STRESS ACTIVATED PROTEIN KINASE; VASCULOTROPIN RECEPTOR 2;

CELL PROLIFERATION; DISEASE COURSE; ENDOTHELIUM CELL; GENE EXPRESSION PROFILING; GENE TARGETING; GENOME ANALYSIS; HISTOGENESIS; HUMAN; HUMAN HERPESVIRUS 8; KAPOSI SARCOMA; PATHOGENESIS; PROTEIN MICROARRAY; SHORT SURVEY; SPINDLE CELL; UPREGULATION; VIRUS INFECTION;

ANIMALS; GENE EXPRESSION PROFILING; GENOME; GENOME, HUMAN; HUMANS; SARCOMA, KAPOSI;

HERPESVIRIDAE;

EID: 9444241469     PISSN: 14656906     EISSN: None     Source Type: Journal    
DOI: 10.1186/gb-2004-5-11-247     Document Type: Short Survey

References (32)

1. Wang H-W, Trotter MWB, Lagos D, Bourboulia D, Henderson S, Mäkinen T, Elliman S, Flanagan AM, Alitalo K, Boshoff C: Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression profile of Kaposi sarcoma. Nat Genet 2004, 36:687-693.
2. Glaunsinger B, Ganem D: Highly selective escape from KSHV-mediated host mRNA shutoff and its implications for viral pathogenesis. J Exp Med 2004, 200:391-398.
3. Poole LJ, Yu Y, Kim PS, Zheng QZ, Pevsner J, Hayward GS: Altered patterns of cellular gene expression in dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus. J Virol 2002, 76:3395-3420.
4. Moses AV, Jarvis MA, Raggo C, Bell YC, Ruhl R, Luukkonen BG, Griffith DJ, Wait CL, Druker BJ, Heinrich MC, et al.: Kaposi's sarcoma-associated herpesvirus-induced up-regulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cells. J Virol 2002, 76 8383-8399.
5. Naranatt PP, Krishman HH, Svojanovsky SR, Bloomer C, Mathur S, Chandran B: Host gene induction and transcriptional reprogramming in Kaposi's sarcoma associated herpesvirus (KSHV/HHV-8)-infected endothelial, fibroblast, and B cells: insights into modulation events early during infection. Cancer Res 2004, 64:72-84.
6. Kaposi M: Idiopathisches multiples Pigmentsarkom der Haut. Arch Dermatol Syphilol 1872, 4:265-278.
7. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS: Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994, 266 1865-1869.
8. Kahn HJ, Bailey D, Marks A: Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas. Mod Pathol 2002, 15:434-440.
9. Uccini S, Ruco LP, Monardo F, Stoppacciaro A, Dejana E, La Parola IL, Cerimele D, Baroni CD: Coexpression of endothelial cell and macrophage antigens in Kaposi's sarcoma cells. J Pathol 1994, 173:23-31.
10. Dupin N, Fisher C, Kellam P, Ariad S, Tulliez M, Franck N, van Marck E, Salmon D, Gorin I, Escande JP, et al.: Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma. Proc Natl Acad Sci USA 1999, 96:4546-4551.
11. Regezi JA, MacPhail LA, Daniels TE, DeSouza YG, Greenspan JS, Greenspan D: Human immunodeficiency virus-associated oral Kaposi's sarcoma. A heterogeneous cell population dominated by spindle-shaped endothelial cells. Am J Pathol 1993, 143:240-249.
12. Kaaya EE, Parravicini C, Ordonez C, Gendelman R, Berti E, Gallo RC, Biberfeld P: Heterogeneity of spindle cells in Kaposi's sarcoma: comparison of cells in lesions and in culture. J Acquir Immune Defic Syndr Hum Retrovirol 1995, 10:295-305.
13. Gallo RC: The enigmas of Kaposi's sarcoma. Science 1998, 282:1837-1839.
14. Salahuddin SZ, Nakamura S, Biberfeld P, Kaplan MH, Markham PD, Larsson L, Gallo RC: Angiogenic properties of Kaposi's sarcoma-derived cells after long-term culture in vitro. Science 1988, 242:430-433.
15. Aboulatia DM: Regression of acquired immunodeficiency syndrome-related pulmonary Kaposi's sarcoma after highly active retroviral therapy. Mayo Clin Proc 1998, 73:439-43.
16. Gill PS, Tsai YC, Rao AP, Spruck CH 3rd, Zheng T, Harrington WA Jr, Cheung T, Nathwani B, Jones PA: Evidence for multiclonality in multicentric Kaposi's sarcoma. Proc Natl Acad Sci USA 1998, 95:8257-8261.
17. Lunardi-Iskandar Y, Bryant JL, Zeman RA, Lam VH, Samaniego F, Besnier JM, Hermans P, Thierry AR, Gill P, Gallo RC: Tumorigenesis nd metastasis of neoplastic Kaposi's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone. Nature 1995, 375 64-68.
18. Benelli R, Albini A, Parravicini C, Carlone S, Repetto L, Tambussi G, Lazzarin A: Isolation of spindle-shaped cell populations from primary cultures of Kaposi's sarcoma of different stage. Cancer Lett 1996, 100:125-32.
19. Bubman D, Cesarman E: Pathogenesis of Kaposi's sarcoma. Hemotol Oncol Clin North Am 2003, 17:717-745.
20. Flore O, Rafii S, Ely S, O'Leary JJ, Hyjek EM, Cesarman E: Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus. Nature 1998, 394:588-592.
21. Ciufo DM, Cannon JS, Poole LJ, Wu FY, Murray P, Ambinder RF, Hayward GS: Spindle cell conversion by Kaposi's sarcoma-associated herpesvirus: formation of colonies and plaques with mixed lytic and latent gene expression in infected primary dermal microvascular endothelial cell cultures. J Virol 2001, 75:5614-5626.
22. Moses AV, Fish KN, Ruhl R, Smith PP, Strussenberg JG, Zhu L, Chandran B, Nelson JA: Long-term infection and transformation of dermal microvascular endothelial cells by human herpesvirus 8. J Virol 1999, 73:6892-6902.
23. Lagunoff M, Bechtel J, Venetsanakos E, Roy AM, Abbey N, Herndier B, McMahon M, Ganem D: De novo infection and serial transmission of Kaposi's sarcoma-associated herpesvirus in cultured endothelial cells. J Virol 2002, 76:2440-2448.
24. Glaunsinger B, Ganem D: Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnover. Mol Cell 2004, 13:713-723.
25. Arvanitakis L, Geras-Raaka E, Varma A, Gershengorn MC, Cesarman E: Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation. Nature 1997, 385:347-350.
26. Bais C, Santomasso B, Coso O, Arvanitakis L, Raaka EG, Gutkind JS, Asch AS, Cesarman E, Mesri EA, Gershengorn MC: G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 1998, 391 86-89.
27. Smit MJ, Verzijl D, Casarosa P, Navis M, Timmerman H, Leurs R: Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor ORF74 constitutively activates p44/p42 MAPK and Akt via G(i) and phospholipase C-dependent signaling pathways. J Virol 2002, 76:1744-1752.
28. Masood R, Cesarman E, Smith DL, Gill PS, Flore O: Human herpesvirus-8-transformed endothelial cells have functionally activated vascular endothelial growth factor/vascular endothelial growth factor receptor. Am J Pathol 2002, 160:23-29.
29. EBI databases - ArrayExpress home [http://www.ebi.ac.uk/arrayexpress]
30. Gene Expression Omnibus (GEO) homepage [http://www.ncbi.nlm.nih.gov/geo]
31. Pevsner lab website [http://www.pevsnerlab.kennedykrieger.org/microarraydata/Hayward]
32. Klaus Früh lab [http://www.ohsu.edu/vgti/fruehkshv.htm]