Evaluation of the clastogenicity and anticlastogenicity of the carotenoid bixin in human lymphocyte cultures

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 585, Issue 1-2, 2005, Pages 113-119

  Antunes, Lusânia M Greggi ^a   Pascoal, Lívia M ^a   Bianchi, Maria De Lourdes P ^b   Dias, Francisca L ^a  

^a FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Annatto; Anticlastogenicity; Bixin; Carotenoid; Chromosomal aberrations; cis Diamminedichloroplatinum (II)

Indexed keywords

ANTIOXIDANT; BIXIN; CAROTENOID; CISPLATIN; FREE RADICAL; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD SAMPLING; CELL CULTURE; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; METAPHASE; MITOSIS INDEX; NORMAL HUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ADOLESCENT; ADULT; ANTIMUTAGENIC AGENTS; CAROTENOIDS; CELLS, CULTURED; CHROMOSOME ABERRATIONS; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LYMPHOCYTES; MALE; MITOTIC INDEX; MUTAGENICITY TESTS; MUTAGENS;

BIXA ORELLANA;

EID: 22144462823     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2005.04.006     Document Type: Article

References (34)

1. H. Sies, and W. Stahl Vitamins E and C, β-carotene, and other carotenoids as antioxidants Am. J. Clin. Nutr. 62 1995 1315S 1321S
2. A.R. Collins Carotenoids and genomic stability Mutat. Res. 475 2001 21 28
3. A.J. Young, and G.M. Lowe Antioxidant and prooxidant properties of carotenoids Arch. Biochem. Biophys. 385 2001 20 27
4. A.S.L. Tirimanna Study of the carotenoid pigments of Bixa orellana L. seeds by thin layer chromatography Mikrochim. Acta 2 1981 11 16
5. A.Z. Mercadante, A. Steck, and H. Pfander Isolation and identification of new apocarotenoids from annatto (Bixa orellana) seeds J. Agric. Food Chem. 45 1997 1050 1054
6. P. Di Mascio, T.P. Devasagayam, S. Kaiser, and H.s Sies Carotenoids, tocopherols and thiols as biological singlet molecular oxygen quenchers Biochem. Soc. Trans. 18 1990 1054 1056
7. A.C.S. Fernandes, C.A. Almeida, F. Albano, G.A.T. Laranja, I. Felzenszwalb, C.L.S. Lage, C.C.N.F. de Sá, A.S. Moura, and K. Kovary Norbixin ingestion did not induce any detectable DNA breakage in liver and kidney but caused a considerable impairment in plasma glucose levels of rats and mice J. Nutr. Biochem. 13 2002 411 420
8. L.R. Ribeiro, and D.M.F. Salvadori Dietary compounds may prevent mutation-related diseases in human Mutat. Res. 544 2003 195 201
9. A.R.P.L. Bautista, E.L.T. Moreira, M.S. Batista, M.S. Miranda, and I.C.S. Gomes Subacute toxicity assessment of annatto in rat Food Chem. Toxicol. 42 2004 625 629
10. F.J.R. Paumgartten, R.R. De-Carvalho, I.B. Araujo, F.M. Pinto, O.O. Borges, C.A.M. Souza, and S.N. Kuriyama Evaluation of the developmental toxicity of annatto in the rat Food Chem. Toxicol. 40 2002 1595 1601
11. R.B. Haveland-Smith Evaluation of the genotoxicity of some natural food colours using bacterial assays Mutat. Res. 91 1981 285 290
12. R.O. Alves de Lima, L. Azevedo, L.R. Ribeiro, and D.M.F. Salvadori Study on the mutagenicity and antimutagenicity of a natural food colour (annatto) in mouse bone marrow cells Food Chem. Toxicol. 41 2003 189 192
13. K.C. Thresiamma, J. George, and R. Kuttan Protective effect of curcumin, ellagic acid and bixin on radiation induced genotoxicity J. Exp. Clin. Cancer Res. 17 1998 431 434
14. C.R. Silva, L.M.G. Antunes, and M.L.P. Bianchi Antioxidant action of bixin against cisplatin-induced chromosome aberrations and lipid peroxidation in rats Pharmacol. Res. 43 2001 561 566
15. P.S. Moorhead, P.C. Nowell, W.J. Mellman, D.P. Batipps, and D.A. Hungeford Chromosome preparations of leukocytes cultured from human peripheral blood Exp. Cell Res. 20 1960 613 616
16. ISCN, International System for Human Cytogenetics Nomenclature, Report of the standing committee on human cytogenetics nomenclature, in: S. Karger (Ed.), Basel, München, Paris, London, New York New Delhi, Singapore, Tokyo, Sydney, 1985, pp. 66-69.
17. G. Obe, P. Pfeiffer, J.R.K. Savage, C. Johannes, W. Goedecke, P. Jeppesen, A.T. Natarajan, W. Martínez-López, G.A. Folle, and M.E. Drets Chromosomal aberrations: formation, identification and distribution Mutat. Res. 504 2002 17 36
18. E. Zeiger Illusions of safety: antimutagens can be mutagens, and anticarcinogens can be carcinogens Mutat. Res. 543 2003 191 194
19. S.H.H. Swierenga, J.A. Heddle, E.A. Sigal, J.P.W. Gilman, R.L. Brillinger, G.R. Douglas, and E.R. Nestmann Recommended protocols based on a survey of current practice in genotoxicity testing laboratories, IV. Chromosome aberration and sister-chromatid exchange in Chinese hamster ovary, V79 Chinese hamster lung and human lymphocyte cultures Mutat. Res. 246 1991 301 322
20. B. Rosenberg Fundamental studies with cisplatin Cancer 55 1985 2303 2315
21. R. Baliga, Z. Zhang, M. Baliga, N. Ueda, and S. Shah In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity Kidney Inter. 53 1998 394 401
22. H. Matsushima, K. Yonemura, K. Ohishi, and A. Hishida The role of oxygen free radicals in cisplatin-induced acute renal failure in rats J. Lab. Clin. Med. 131 1998 518 526
23. N.I. Weijl, G.D. Hopman, A. Wipkink-Bakker, E.G. Lentjes, H.M. Berger, F.J. Cleton, and S. Osanto Cisplatin combination chemotherapy induces a fall in plasma antioxidants of cancer patients Ann. Oncol. 9 1998 1331 1337
24. T. Ohe, S. Tsuda, Y. Sakata, M. Taniwaki, S. Misawa, and T. Abe cis-Diamminedichloroplatinum(II)-induced sister-chromatid exchanges and chromosome aberration formation in cultured human lymphocytes and their inhibition by sodium thiosulfate Mutat. Res. 244 1990 279 285
25. L.M.G. Antunes, M.C.P. Araújo, J.D.C. Darin, and M.L.P. Bianchi Effects of the antioxidants curcumin and vitamin C on cisplatin-induced clastogenesis in Wistar rat bone marrow cells Mutat. Res. 465 2000 131 137
26. H. Nefic Anticlastogenic effect of vitamin C on cisplatin induced chromosome aberrations in human lymphocyte cultures Mutat. Res. 498 2001 89 98
27. B. Kosminder, K. Wyszynska, E. Janik-Spiechowicz, R. Osiecka, E. Zyner, J. Ochocki, E. Ciesielska, and W. Wasowicz Evaluation of the genotoxicity of cis-bis(3-aminoflavone)dichloroplatinum(II) in comparison with cis-DDP Mutat. Res. 558 2004 93 110
28. L.M.G. Antunes, J.D.C. Darin, and M.L.P. Bianchi Protective effects of vitamin C against cisplatin-induced nephrotoxicity and lipid peroxidation in adult rats: a dose-dependent study Pharmacol. Res. 41 2000 405 411
29. N.I. Weijl, F.J. Cleton, and S. Osanto Free radicals and antioxidants in chemotherapy-induced toxicity Cancer Treat. Rev. 23 1997 209 240
30. G.S. Baldew, J.G. McVie, M.A. Van der Valk, G. Los, J.J. De Goeij, and N.P.E. Vermeulen Selective reduction of cis-diamminedichloroplatinun(II) nephrotoxicity by ebselen Cancer Res. 50 1990 7031 7036
31. M. Satoh, A. Naganuma, and N. Imura Effect of coadministration of selenite on the toxicity and antitumor activity of cis- diamminedichloroplatinun(II) given repeatedly to mice Cancer Chemother. Pharmacol. 30 1992 439 443
32. E. Gebhart, H. Wagner, K. Grziwok, and H. Behnsen The action of anticlastogens in human lymphocyte cultures and their modification by rat-liver S9 mix Mutat. Res. 149 1985 83 94
33. O.I. Aruoma Methodological considerations for characterizing potential antioxidant actions of bioactive components in plant foods Mutat. Res. 523 2003 9 20
34. K. Wozniak, A. Czechowska, and J. Blasiak Cisplatin-evoked DNA fragmentation in normal and cancer cells and its modulation by free radical scavengers and the tyrosine kinase inhibitor STI571 Chem. Biol. Int. 147 2004 309 318