Platelet serotonin and monoamine oxidase activity in patients with early and late onset Alzheimer's disease

Periodicum Biologorum

Volumn 107, Issue 2, 2005, Pages 211-215

  Mimica, Ninoslav ^a,b   Mück Šeler, Dorotea ^c   Pivac, Nela ^c   Mustapić, Maja ^c   Folnegović Šmalc, Vera ^a,b  

^a Referentni centar za Alzheimerovu bolest i psihijatriju sta rijeivo t ne dobi   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

^c RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

Alzheimer's disease; Dementia; Early onset; Late onset; Monoamine oxidase; Platelets; Serotonin

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; BIOCHEMICAL MARKER; SEROTONIN;

ADULT; AGED; ALZHEIMER DISEASE; CLINICAL FEATURE; COGNITION; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; ONSET AGE; PROTEIN LOCALIZATION; SPECTROFLUOROMETRY; STATISTICAL SIGNIFICANCE; THROMBOCYTE;

EID: 22144453614     PISSN: 00315362     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (35)

1. ADOLFSSON R, GOTTFRIES C G, ORELAND L, WIBERG A, WINBLAD B 1980 Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type. Life Sci 27: 1029-1034
2. AMERICAN PSYCHIATRIC ASSOCIATION 2000 Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. American Psychiatric Association, Washington, DC
3. ANDERSSON A, ADOLFSSON R, ERIKSSON K, MARCUSSON J 1991 Platelet [3H] paroxetine binding to 5-HT uptake sites in Alzheimer's disease. Neurobiology of Aging 12: 531-534
4. 2 receptor binding properties and their regulation by endogenous serotonin. Life Sci 52: 313-321
5. ARAI H, KOSAKA K, IZUKA R 1984 Changes of biogenic amines and their metabolites in postmortem brains from patients with Alzheimer type dementia. J Neurochem 43: 388-393
6. ARORA RC, EMERY O, MELTZER HY 1991 Serotonin uptake in the blood platelets of Alzheimer's disease. Neurology 41: 1307-1309
7. BALCIUNIENE J, EMILSSON L, ORELAND L, PETTERSSON U, JAZIN E 2002 Investigation of the functional effect of monoamine oxidase polymorphisms in human brain. Hum Genet 110: 1-7
8. BONGIOANNI P, GEMIGNANI F, BOCCARDI B, BORGNA M, ROSSIB 1997 Platelet monoamine oxidase molecular activity in demented patients. Ital J Neurol Sci 18: 151-156
9. BURKE W J, WEN LI S, CHUNG H D, RUGGIERO D A, KRISTAL B S, JOHNSON E M, LAMPE P, KUMAR V B, FRANKO M, WILLIAMS E A, ZAHM D S 2004 Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: Role in neurodegenerative diseases. NeuroToxicology 25: 101-115
10. CHEN C P L H, EASTWOOD S L, HOPE T, MCDONALD B, FRANCIS P T, ESIRI M M 2000. Immunocytochemical study of the dorsal and median raphe nuclei in patients with Alzheimer's disease prospectively assessed for behavioural changes. Neuropathol Appl Neurobiol 26: 1-10
11. DANIELCZYK W, STREIFLER M, KONRADI C, RIEDERE P, MOLL G 1988 Platelet MAO B activity and the psychopathology of Parkinson's disease, senile dementia and multiinfarction dementia. Acta Psychiat Scand 78: 730-736
12. EKBLOM J, GARPENSTRAND H, DAMBERG M, CHEN K, SHIH J C, ORELAND L 1998 Transcription factor binding to the core promoter of the human monoamine oxidase B gene in the cerebral cortex and in blood cells. Neurosci Lett 258: 101-104
13. FOLSTEIN M F, FOLSTEIN S E, MCHUGH P R 1975 Mini mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198
14. FRANKE L, SCHEWE H.-J, MÜLLER B, CAMPMAN V, KITZROW W, UEBELHACK R, BERGHÖFER A, MÜLLER-OERLINGHAUSEN B 2000 Serotonergic platelet variables in unmedicated patients suffering from major depression and healthy subjects. Relationship between 5HT content and 5HT uptake. Life Sci 47: 301-315
15. GARZIA-ALLOZA M, GIL-BEA F-J, DIEZ-ARIZA M, CHEN C P L H, FRANCIS P T, LASHERAS B, RAMIREZ M J 2004 Cholinergic-serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer's disease. Neuropsychologia (in press) (online on Sci Direct)
16. KENNEDY B P, ZIEGLER M G, HANSEN L A, THAL L J, MASLIAH E 2003 Early and persistent alterations in prefrontal cortex MAO A and B in Alzheimer's disease. J Neural Transm 110: 789-801
17. KOREN P, DIVER-HARBER A, ADUNSKY A, RABINOWITZ M, HERSHKOWITZ M 1993 Uptake of serotonin into platelets of senile dementia of the Alzheimer type patients. J Gerontol 48: B93-B96
18. KOZUMPLIK O, UZUN S, FOLNEGOVIĆ-ŠMALC V, JUKIĆ V, MIMICA N 2003 Clinical diagnosis of Alzheimer's disease: importance of rating instruments. Neurol Croat 52: 45-46
19. KRAJL M 1965 A rapid microfluorimetric determination of monoamine oxidase. Biochem Pharmacol 14: 1683-1685
20. KUMAR A, WEISS S, FERNANDES J B, CRUESS D, EISDORFER C 1998 Peripheral serotonin levels in women: role of aging and ethnicity. Gerontology 44: 211-216
21. LOWRY O H, ROSENBROUGH N S, FARR A C, RANDALL R J 1951 Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-75
22. MCKHANN G, DRACHMANN D, FOLSTEIN M, KATZMAN R, PRICE D, STADLAN E M 1984 Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944
23. MIMICA N, MÜCK-ŠELER D, PIVAC N, MUSTAPIĆ M, FOLNEGOVIĆ-ŠMALC V 2004 Platelet serotonin and platelet MAO activity in patients with early- and late-onset of Alzheimer's disease. Period biol 106 (Suppl 1): 126
24. MIMICA N, MÜCK-ŠELER D, PIVAC N, MUSTAPIĆ M, ŠAGUD M, FOLNEGOVIĆ-ŠMALC V, JAKOVLJEVIĆ M 2003 Platelet serotonin and platelet MAO-B activity in Alzheimer's disease. Neural Croat 52(Suppl 4): 47
25. MÜCK-ŠELER D, BUJAS M, LJUBIĆ-THIBAL V, JAKOVLJEVIĆ M 1996 Effect of age on platelet 5-HT concentrations on healthy controls, depressed and schizophrenic patients. Neuropsychobiology 34:201-203
26. MÜCK-ŠELER D, PIVAC N, MIMICA N, MUSTAPIĆ M, FOLNEGOVIĆ-ŠMALC V 2004 Platelet serotonin and MAO-B activity in Alzheimer's disease. Int J Neuropsychopharmacol 7 (Suppl 1): S383-S384
27. MÜCK-ŠELER D, PIVAC N, ŠAGUD M, JAKOVLJEVIĆ M, MIHALJEVIĆ-PELEŠ A 2002 The effects of paroxetine and tianeptine on peripheral biochemical markers in major depression. Prog Neuropsychopharmacol Biol Psychiat 26: 1235-1243
28. ORELAND L, GOTTFRIES C G 1986 Platelet and brain monoamine oxidase in aging and in dementia of Alzheimer's type. Prog Neuropsychopharmacol Biol Psychiat 10: 533-540
29. PIVAC N, MÜCK-ŠELER D, MUSTAPIĆ M, MIMICA N, ŠAGUD M, FOLNEGOVIĆ-ŠMALC V, MIHALJEVIĆ-PELEŠ A, JAKOVLJEVIĆ M 2004 Peripheral biochemical markers in Alzheimer's disease. Eur Psychiatry 19 (Suppl 1): 152S
30. ROBINSON D S, DAVIS J M, NIES A, RAVARIS C L, SYLWESTER D 1971 Relation of sex and aging to monoamine oxidase activity of human brain, plasma and platelets. Arch Gen Psychiatry 24: 536-539
31. SCHURR A S, HO B T, SCHOOLAR J C 1980 Human brain monoamine oxidase: one molecular entity-multiple binding sites? J Pharm Pharmacol 33: 165-168
32. STAHL S M 1985 Platelets as pharmacological models for the receptors and biochemistry of monoaminergic neurons. In: Longenecker G L (ed), Platelets: Physiology and Pharmacology. Academic Press, New York, 1985, p 307-340
33. SVJETSKA ZDRAVSTVENA ORGANIZACIJA 1999 Klasifikacija mentalnih poremećaja i poremećaja ponašanja (MKB-10): klinički opisi i dijagnostičke smjernice - Deseta revizija. Medicinska naklada, Zagreb.
34. THE RONALD AND NANCY REAGAN RESEARCH INSTITUTE OF THE ALZHEIMERS ASSOCIATION AND THE NATIONAL INSTITUTE ON AGING WORKING GROUP 1998 Consensus report of the working group on molecular and biochemical markers of Alzheimer's disease. Neurobiol Aging 19: 109-116
35. ZELLER E A, BOSHES B, ARBIT J, BIEBER M, BLONDSKY E R, DOLKART M, HUPRIKAR S V 1976 Effect of parkinsonism, age, sex, and L-dopa on platelet monoamine oxidase. J Neural Transm 39: 63-68