Radiosynthesis, in vitro cellular uptake and in vivo biodistribution of 3′-O-(3-benzenesulfonylfuroxan-4-yl)-5-[125I]iodo-2′- deoxyuridine, a nucleoside-based nitric oxide donor

Nuclear Medicine and Biology

Volumn 32, Issue 6, 2005, Pages 641-645

  Moharram, Sameh ^a   Zhou, Aihua ^a   Kumar, Piyush ^a   Knaus, Edward E ^a   Wiebe, Leonard I ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Benzenesulfonylfuroxanyl NO donor; Iododeoxyuridine; IUDR; NO; Nucleic acid fraction; Tumor uptake

Indexed keywords

3' O (3 BENZENESULFONYLFUROXAN 4 YL) 5 IODO 2' DEOXYURIDINE I 125; ALBUMIN; IODINE 125; NITRIC OXIDE DONOR; NUCLEIC ACID; NUCLEOSIDE; TRACER; UNCLASSIFIED DRUG; URIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CHEMICAL REACTION; CONTROLLED STUDY; DECOMPOSITION; DEIODINATION; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; DRUG UPTAKE; EXPERIMENTAL NEOPLASM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE; KIDNEY; LIVER; MOUSE; NONHUMAN; PROTEIN BINDING; RADIOACTIVITY; RADIOCHEMISTRY; STOMACH; THYROID GLAND; TIME SERIES ANALYSIS; TUMOR CELL;

ANIMALS; IDOXURIDINE; IODINE RADIOISOTOPES; ISOTOPE LABELING; MALE; MICE; MICE, INBRED BALB C; NITRIC OXIDE DONORS; OXADIAZOLES; POSITRON-EMISSION TOMOGRAPHY; RADIOIMMUNODETECTION; SARCOMA, EXPERIMENTAL; TUMOR CELLS, CULTURED;

EID: 22144444514     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2005.04.011     Document Type: Article

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