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Volumn 80, Issue 1, 2005, Pages 102-109

Sensitization with xenogeneic tissues alters the heavy chain repertoire of human anti-Galα1-3Gal antibodies

Author keywords

Antibodies; Hapten; Heavy chain; Repertoire; Xenotransplantation

Indexed keywords

ANTIBODY; GALACTOSYLGALACTOSE; GALACTOSYLGALACTOSE ANTIBODY; HAPTEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN M; UNCLASSIFIED DRUG;

EID: 22144437352     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000162976.07023.6D     Document Type: Article
Times cited : (9)

References (57)
  • 1
    • 0023161406 scopus 로고
    • Mutation drift and repertoire shift in the maturation of the immune response
    • Berek C, Milstein C. Mutation drift and repertoire shift in the maturation of the immune response. Immunol Rev 1987; 96: 23.
    • (1987) Immunol Rev , vol.96 , pp. 23
    • Berek, C.1    Milstein, C.2
  • 2
    • 0030240108 scopus 로고    scopus 로고
    • Avidity maturation, repertoire shift, and strain differences in antibodies to bacterial levan, a type 2 thymus-independent polysaccharide antigen
    • Boswell CM, Stein KE. Avidity maturation, repertoire shift, and strain differences in antibodies to bacterial levan, a type 2 thymus-independent polysaccharide antigen. J Immunol 1996; 157: 1996.
    • (1996) J Immunol , vol.157 , pp. 1996
    • Boswell, C.M.1    Stein, K.E.2
  • 3
    • 0034686496 scopus 로고    scopus 로고
    • The structural basis of repertoire shift in an immune response to phosphocholine
    • Brown M, Schumacher MA, Wiens GD, et al. The structural basis of repertoire shift in an immune response to phosphocholine. J Exp Med 2000; 191: 2101.
    • (2000) J Exp Med , vol.191 , pp. 2101
    • Brown, M.1    Schumacher, M.A.2    Wiens, G.D.3
  • 4
    • 0037884814 scopus 로고    scopus 로고
    • Repertoire shift in the humoral response to phosphocholine-keyhole limpet hemocyanin: VH somatic mutation in germinal center B cells impairs T15 Ig function
    • Wiens GD, Brown M, Rittenberg MB. Repertoire shift in the humoral response to phosphocholine-keyhole limpet hemocyanin: VH somatic mutation in germinal center B cells impairs T15 Ig function. J Immunol 2003; 170: 5095.
    • (2003) J Immunol , vol.170 , pp. 5095
    • Wiens, G.D.1    Brown, M.2    Rittenberg, M.B.3
  • 5
    • 0035817384 scopus 로고    scopus 로고
    • Somatic hypermutation shapes the antibody repertoire of memory B cells in humans
    • Meffre E, Catalan N, Seltz F, et al. Somatic hypermutation shapes the antibody repertoire of memory B cells in humans. J Exp Med 2001; 194: 375.
    • (2001) J Exp Med , vol.194 , pp. 375
    • Meffre, E.1    Catalan, N.2    Seltz, F.3
  • 6
    • 0026049326 scopus 로고
    • Variable region diversity in human circulating antibodies specific for the capsular polysaccharide of Haemophilus influenzae type b. Preferential usage of two types of VH3 heavy chains
    • Silverman GJ, Lucas AH. Variable region diversity in human circulating antibodies specific for the capsular polysaccharide of Haemophilus influenzae type b. Preferential usage of two types of VH3 heavy chains. J Clin Invest 1991; 88: 911.
    • (1991) J Clin Invest , vol.88 , pp. 911
    • Silverman, G.J.1    Lucas, A.H.2
  • 7
    • 0027022656 scopus 로고
    • The repertoire of human antibody to the Haemophilus influenzae type b capsular polysaccharide
    • Insel RA, Adderson EE, Carroll WL. The repertoire of human antibody to the Haemophilus influenzae type b capsular polysaccharide. Int Rev Immunol 1992; 9: 25.
    • (1992) Int Rev Immunol , vol.9 , pp. 25
    • Insel, R.A.1    Adderson, E.E.2    Carroll, W.L.3
  • 8
    • 0028828196 scopus 로고
    • The V-region repertoire of Haemophilus influenzae type b polysaccharide antibodies induced by immunization of infants
    • Chung GH, Kim KH, Daum RS, et al. The V-region repertoire of Haemophilus influenzae type b polysaccharide antibodies induced by immunization of infants. Infect Immun 1995; 63: 4219.
    • (1995) Infect Immun , vol.63 , pp. 4219
    • Chung, G.H.1    Kim, K.H.2    Daum, R.S.3
  • 9
    • 0028968094 scopus 로고
    • Predominant V-region gene configurations in the human antibody response to Haemophilus influenzae capsule polysaccharide
    • Pinchuk GV, Nottenburg C, Milner EC. Predominant V-region gene configurations in the human antibody response to Haemophilus influenzae capsule polysaccharide. Scand J Immunol 1995; 41: 324.
    • (1995) Scand J Immunol , vol.41 , pp. 324
    • Pinchuk, G.V.1    Nottenburg, C.2    Milner, E.C.3
  • 10
    • 0000665022 scopus 로고
    • Evolutionary relationship between the natural anti-Gal antibody and the Gal α1-3Gal epitope in primates
    • Galili U, Clark MR, Shohet SB, et al. Evolutionary relationship between the natural anti-Gal antibody and the Gal α1-3Gal epitope in primates. Proceedings of the National Academy of Science, USA 1987; 84: 1369.
    • (1987) Proceedings of the National Academy of Science, USA , vol.84 , pp. 1369
    • Galili, U.1    Clark, M.R.2    Shohet, S.B.3
  • 11
    • 0030844567 scopus 로고    scopus 로고
    • Specificity and function of "natural" antibodies in immunodeficient subjects: Clues to B cell lineage and development
    • Parker W, Yu PB, Holzknecht ZE, et al. Specificity and function of "natural" antibodies in immunodeficient subjects: clues to B cell lineage and development. J Clin Immunol 1997; 17: 311.
    • (1997) J Clin Immunol , vol.17 , pp. 311
    • Parker, W.1    Yu, P.B.2    Holzknecht, Z.E.3
  • 12
    • 0013986472 scopus 로고
    • Natural antibodies and the immune response
    • Boyden SV. Natural antibodies and the immune response. Adv Immunol 1966; 5: 1.
    • (1966) Adv Immunol , vol.5 , pp. 1
    • Boyden, S.V.1
  • 13
    • 0025905663 scopus 로고
    • Natural autoantibodies: From 'horror autotoxicus' to 'gnothi seauton'
    • Avrameas S. Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'. Immunology Today 1991; 12: 154.
    • (1991) Immunology Today , vol.12 , pp. 154
    • Avrameas, S.1
  • 14
    • 0032445137 scopus 로고    scopus 로고
    • A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection
    • Boes M, Prodeus AP, Schmidt T, et al. A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection. J Exp Med 1998; 188: 2381.
    • (1998) J Exp Med , vol.188 , pp. 2381
    • Boes, M.1    Prodeus, A.P.2    Schmidt, T.3
  • 15
    • 0033515101 scopus 로고    scopus 로고
    • Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system
    • Baumgarth N, Herman OC, Jager GC, et al. Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system. Proc Natl Acad Sci USA 1999; 96: 2250.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2250
    • Baumgarth, N.1    Herman, O.C.2    Jager, G.C.3
  • 16
    • 0032006898 scopus 로고    scopus 로고
    • Linkages of innate and adaptive immunity
    • Carroll MC, Prodeus AP. Linkages of innate and adaptive immunity. Curr Opin Immunol 1998; 10: 36.
    • (1998) Curr Opin Immunol , vol.10 , pp. 36
    • Carroll, M.C.1    Prodeus, A.P.2
  • 17
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • Fearon DT, Locksley RM. The instructive role of innate immunity in the acquired immune response. Science 1996; 272: 50.
    • (1996) Science , vol.272 , pp. 50
    • Fearon, D.T.1    Locksley, R.M.2
  • 18
  • 19
    • 0027944492 scopus 로고
    • Characterization and affinity isolation of xenoreactive human natural antibodies
    • Parker W, Bruno D, Holzknecht ZE, Platt JL. Characterization and affinity isolation of xenoreactive human natural antibodies. Journal of Immunology 1994; 153: 3791.
    • (1994) Journal of Immunology , vol.153 , pp. 3791
    • Parker, W.1    Bruno, D.2    Holzknecht, Z.E.3    Platt, J.L.4
  • 20
    • 0022656044 scopus 로고
    • The natural anti-α-galactosyl IgG on human normal senescent red blood cells
    • Galili U, Flechner I, Knyszynski A, et al. The natural anti-α-galactosyl IgG on human normal senescent red blood cells. British Journal of Haematology 1986; 62: 317.
    • (1986) British Journal of Haematology , vol.62 , pp. 317
    • Galili, U.1    Flechner, I.2    Knyszynski, A.3
  • 21
    • 0024508511 scopus 로고
    • Immunogenic Gal alpha 1-3Gal carbohydrate epitopes are present on pathogenic American Trypanosoma and Leishmania
    • Avila JL, Rojas M, Galili U. Immunogenic Gal alpha 1-3Gal carbohydrate epitopes are present on pathogenic American Trypanosoma and Leishmania. J Immunol 1989; 142: 2828.
    • (1989) J Immunol , vol.142 , pp. 2828
    • Avila, J.L.1    Rojas, M.2    Galili, U.3
  • 22
    • 0028804822 scopus 로고
    • A novel mechanism of retrovirus inactivation in human serum mediated by anti-α-galactosyl natural antibody
    • Rother RP, Fodor WL, Springhorn JP, et al. A novel mechanism of retrovirus inactivation in human serum mediated by anti-α-galactosyl natural antibody. Journal of Experimental Medicine 1995; 182: 1345.
    • (1995) Journal of Experimental Medicine , vol.182 , pp. 1345
    • Rother, R.P.1    Fodor, W.L.2    Springhorn, J.P.3
  • 23
    • 0027135892 scopus 로고
    • Identification of α-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: Relevance to discordant xenografting in man
    • Cooper DKC, Good AH, Koren E, et al. Identification of α-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man. Transplant Immunology 1993; 1: 198.
    • (1993) Transplant Immunology , vol.1 , pp. 198
    • Cooper, D.K.C.1    Good, A.H.2    Koren, E.3
  • 25
    • 0001663079 scopus 로고
    • Origin of naturally occurring hemagglutinins and hemolysins: A review
    • Wiener AS. Origin of naturally occurring hemagglutinins and hemolysins: a review. Journal of Immunology 1951; 66: 287.
    • (1951) Journal of Immunology , vol.66 , pp. 287
    • Wiener, A.S.1
  • 27
    • 0000153901 scopus 로고
    • Some histological and functional aspects of lymphoid tissue in germfree animals. I. Morphological studies
    • Thorbecke GJ. Some histological and functional aspects of lymphoid tissue in germfree animals. I. Morphological studies. Ann N Y Acad Sci 1959; 78: 237.
    • (1959) Ann N Y Acad Sci , vol.78 , pp. 237
    • Thorbecke, G.J.1
  • 28
    • 0027508081 scopus 로고
    • Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: A major obstacle for xenotransplantation in humans
    • Galili U. Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation in humans. Immunology Today 1993; 14: 480.
    • (1993) Immunology Today , vol.14 , pp. 480
    • Galili, U.1
  • 29
    • 0029056034 scopus 로고
    • Increased anti-gal activity in diabetic patients transplanted with fetal porcine islet cell clusters
    • Galili U, Tibell A, Samuelsson B, et al. Increased anti-gal activity in diabetic patients transplanted with fetal porcine islet cell clusters. Transplantation 1995; 59: 1549.
    • (1995) Transplantation , vol.59 , pp. 1549
    • Galili, U.1    Tibell, A.2    Samuelsson, B.3
  • 30
    • 0032944909 scopus 로고    scopus 로고
    • Immunochemical properties of anti-Galα1-3Gal after sensitization with xenogeneic tissues
    • Yu PB, Parker W, Everett M, et al. Immunochemical properties of anti-Galα1-3Gal after sensitization with xenogeneic tissues. Journal of Clinical Immunology 1999; 19: 116.
    • (1999) Journal of Clinical Immunology , vol.19 , pp. 116
    • Yu, P.B.1    Parker, W.2    Everett, M.3
  • 31
    • 0035865120 scopus 로고    scopus 로고
    • Biophysical characteristics of anti-Gal(alpha)1-3Gal IgM binding to cell surfaces: Implications for xenotransplantation
    • Parker W, Stitzenberg KB, Yu PB, et al. Biophysical characteristics of anti-Gal(alpha)1-3Gal IgM binding to cell surfaces: implications for xenotransplantation. Transplantation 2001; 71: 440.
    • (2001) Transplantation , vol.71 , pp. 440
    • Parker, W.1    Stitzenberg, K.B.2    Yu, P.B.3
  • 32
    • 0022260876 scopus 로고
    • Human natural anti-α-galactosyl IgG. II. The specific recognition of α(1-3)-linked glactose residues
    • Galili U, Macher BA, Buehler J, et al. Human natural anti-α- galactosyl IgG. II. the specific recognition of α(1-3)-linked glactose residues. Journal of Experimental Medicine 1985; 162: 573.
    • (1985) Journal of Experimental Medicine , vol.162 , pp. 573
    • Galili, U.1    Macher, B.A.2    Buehler, J.3
  • 34
    • 0030827493 scopus 로고    scopus 로고
    • Cloning of anti-Gal Fabs from combinatorial phage display libraries: Structural analysis and comparison of Fab expression in pComb3H and pComb8 phage
    • Wang L, Radic MZ, Siegel D, et al. Cloning of anti-Gal Fabs from combinatorial phage display libraries: structural analysis and comparison of Fab expression in pComb3H and pComb8 phage. Mol Immunol 1997; 34: 609.
    • (1997) Mol Immunol , vol.34 , pp. 609
    • Wang, L.1    Radic, M.Z.2    Siegel, D.3
  • 35
    • 0032845226 scopus 로고    scopus 로고
    • The human antibody response to porcine xenoantigens is encoded by IGHV3-11 and IGHV3-74 IgVH germline progenitors
    • Kearns-Jonker M, Swensson J, Ghiuzeli C, et al. The human antibody response to porcine xenoantigens is encoded by IGHV3-11 and IGHV3-74 IgVH germline progenitors. Journal of Immunology 1999; 163: 4399.
    • (1999) Journal of Immunology , vol.163 , pp. 4399
    • Kearns-Jonker, M.1    Swensson, J.2    Ghiuzeli, C.3
  • 36
    • 0024204995 scopus 로고
    • Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity
    • Silverman GJ, Goni F, Fernandez J, et al. Distinct patterns of heavy chain variable region subgroup use by human monoclonal autoantibodies of different specificity. J Exp Med 1988; 168: 2361.
    • (1988) J Exp Med , vol.168 , pp. 2361
    • Silverman, G.J.1    Goni, F.2    Fernandez, J.3
  • 38
    • 0028364224 scopus 로고
    • Treatment of hepatic failure with ex vivo pig-liver perfusion followed by liver transplantation
    • Chari RS, Collins BH, Magee JC, et al. Treatment of hepatic failure with ex vivo pig-liver perfusion followed by liver transplantation. New England Journal of Medicine 1994; 331: 234.
    • (1994) New England Journal of Medicine , vol.331 , pp. 234
    • Chari, R.S.1    Collins, B.H.2    Magee, J.C.3
  • 39
    • 0028825231 scopus 로고
    • The humoral immune response in humans following cross-perfusion of porcine organs
    • Cotterell AH, Collins BH, Parker W, et al. The humoral immune response in humans following cross-perfusion of porcine organs. Transplantation 1995; 60: 861.
    • (1995) Transplantation , vol.60 , pp. 861
    • Cotterell, A.H.1    Collins, B.H.2    Parker, W.3
  • 40
    • 85025387592 scopus 로고
    • The precipitin reaction between type III pneumococcus polysaccharide and homologous antibody. II. Conditions for quantitative precipitation of antibody in horse sera
    • Heidelberger MaK. The precipitin reaction between type III pneumococcus polysaccharide and homologous antibody. II. Conditions for quantitative precipitation of antibody in horse sera. Journal of Experimental Medicine 1935; 61: 559.
    • (1935) Journal of Experimental Medicine , vol.61 , pp. 559
    • Heidelberger, Ma.K.1
  • 41
    • 0028986982 scopus 로고
    • The human immunoglobulin VH repertoire
    • Cook GP, Tomlinson IM. The human immunoglobulin VH repertoire. Immunol Today 1995; 16: 237.
    • (1995) Immunol Today , vol.16 , pp. 237
    • Cook, G.P.1    Tomlinson, I.M.2
  • 42
    • 0030610529 scopus 로고    scopus 로고
    • Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells
    • Brezinschek HP, Foster SJ, Brezinschek RI, et al. Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells. J Clin Invest 1997; 99: 2488.
    • (1997) J Clin Invest , vol.99 , pp. 2488
    • Brezinschek, H.P.1    Foster, S.J.2    Brezinschek, R.I.3
  • 43
    • 0032849635 scopus 로고    scopus 로고
    • Naturally occurring anti-α-galactosyl antibodies: Relationship to xenoreactive anti-a-galactosyl antibodies
    • Parker W, Lin SS, Yu PB, et al. Naturally occurring anti-α- galactosyl antibodies: relationship to xenoreactive anti-a-galactosyl antibodies. Glycobiology 1999; 9: 865.
    • (1999) Glycobiology , vol.9 , pp. 865
    • Parker, W.1    Lin, S.S.2    Yu, P.B.3
  • 44
    • 0024805630 scopus 로고
    • Cold agglutinins: Specificity, idiotypy and structural analysis
    • Silverman GJ, Chen PP, Carson DA. Cold agglutinins: specificity, idiotypy and structural analysis. Chem Immunol 1990; 48: 109.
    • (1990) Chem Immunol , vol.48 , pp. 109
    • Silverman, G.J.1    Chen, P.P.2    Carson, D.A.3
  • 45
    • 0023785127 scopus 로고
    • Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans
    • Silverman GJ, Goldfien RD, Chen P, et al. Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans. J Clin Invest 1988; 82: 469.
    • (1988) J Clin Invest , vol.82 , pp. 469
    • Silverman, G.J.1    Goldfien, R.D.2    Chen, P.3
  • 46
    • 0025144869 scopus 로고
    • Structural characterization of the second major cross-reactive idiotype group of human rheumatoid factors. Association with the VH4 gene family
    • Silverman GJ, Schrohenloher RE, Accavitti MA, et al. Structural characterization of the second major cross-reactive idiotype group of human rheumatoid factors. Association with the VH4 gene family. Arthritis Rheum 1990; 33: 1347.
    • (1990) Arthritis Rheum , vol.33 , pp. 1347
    • Silverman, G.J.1    Schrohenloher, R.E.2    Accavitti, M.A.3
  • 47
    • 0028597554 scopus 로고
    • Mechanisms of injury in porcine livers perfused with blood of humans with fulminant hepatic failure
    • Collins BH, Chari RS, Magee JC, et al. Mechanisms of injury in porcine livers perfused with blood of humans with fulminant hepatic failure. Transplantation 1994; 58: 1162.
    • (1994) Transplantation , vol.58 , pp. 1162
    • Collins, B.H.1    Chari, R.S.2    Magee, J.C.3
  • 48
    • 0030852709 scopus 로고    scopus 로고
    • Heterogeneity of human anti-pig natural antibodies cross-reactive with the Gal(alpha1,3)Galactose epitope
    • McMorrow IM, Comrack CA, Sachs DH, et al. Heterogeneity of human anti-pig natural antibodies cross-reactive with the Gal(alpha1,3)Galactose epitope. Transplantation 1997; 64: 501.
    • (1997) Transplantation , vol.64 , pp. 501
    • McMorrow, I.M.1    Comrack, C.A.2    Sachs, D.H.3
  • 49
    • 0023510298 scopus 로고
    • Evolutionary and somatic selection of the antibody repertoire in the mouse
    • Rajewsky K, Forster I, Cumano A. Evolutionary and somatic selection of the antibody repertoire in the mouse. Science 1987; 238: 1088.
    • (1987) Science , vol.238 , pp. 1088
    • Rajewsky, K.1    Forster, I.2    Cumano, A.3
  • 50
    • 0036533341 scopus 로고    scopus 로고
    • Somatic immunoglobulin hypermutation
    • Diaz M, Casali P. Somatic immunoglobulin hypermutation. Curr Opin Immunol 2002; 14: 235.
    • (2002) Curr Opin Immunol , vol.14 , pp. 235
    • Diaz, M.1    Casali, P.2
  • 52
    • 0027191386 scopus 로고
    • Anti-DNA antibodies secreted by peripheral B cells of lupus patients have both normal and lupus-specific features
    • Livneh A, Or G, Many A, et al. Anti-DNA antibodies secreted by peripheral B cells of lupus patients have both normal and lupus-specific features. Clin Immunol Immunopathol 1993; 68: 68.
    • (1993) Clin Immunol Immunopathol , vol.68 , pp. 68
    • Livneh, A.1    Or, G.2    Many, A.3
  • 53
    • 0028122220 scopus 로고
    • Clonotypic dominance and variable gene elements of pathogenic anti-DNA autoantibodies from a single patient with lupus
    • Chastagner P, Demaison C, Theze J, et al. Clonotypic dominance and variable gene elements of pathogenic anti-DNA autoantibodies from a single patient with lupus. Scand J Immunol 1994; 39: 165.
    • (1994) Scand J Immunol , vol.39 , pp. 165
    • Chastagner, P.1    Demaison, C.2    Theze, J.3
  • 54
    • 0023652330 scopus 로고
    • Diversity achieved by diverse mechanisms: Gene conversion in developing B cells of the chicken
    • Maizels N. Diversity achieved by diverse mechanisms: gene conversion in developing B cells of the chicken. Cell 1987; 48: 359.
    • (1987) Cell , vol.48 , pp. 359
    • Maizels, N.1
  • 55
    • 0036718611 scopus 로고    scopus 로고
    • Comparative analyses of immunoglobulin genes: Surprises and portents
    • Flajnik MF. Comparative analyses of immunoglobulin genes: surprises and portents. Nat Rev Immunol 2002; 2: 688.
    • (2002) Nat Rev Immunol , vol.2 , pp. 688
    • Flajnik, M.F.1
  • 56
    • 0037105445 scopus 로고    scopus 로고
    • Gene conversion-like sequence transfers between transgenic antibody V genes are independent of RAD54
    • D'Avirro N, Truong D, Luong M, et al. Gene conversion-like sequence transfers between transgenic antibody V genes are independent of RAD54. J Immunol 2002; 169: 3069.
    • (2002) J Immunol , vol.169 , pp. 3069
    • D'Avirro, N.1    Truong, D.2    Luong, M.3
  • 57
    • 0027367160 scopus 로고
    • One percent of human circulating B lymphocytes are capable of producing the natural anti-gal antibody
    • Galili U, Anaraki F, Thall A, et al. One percent of human circulating B lymphocytes are capable of producing the natural anti-gal antibody. Blood 1993; 82: 2485.
    • (1993) Blood , vol.82 , pp. 2485
    • Galili, U.1    Anaraki, F.2    Thall, A.3


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