-
1
-
-
0030789850
-
Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell esophageal cancer
-
Bleiberg H, Conroy T, Paillot B, Lacave AJ, Blijham G, Jacob JH, Bedenne L, Namer M, De Besi P, Gay F, Collette L, Sahmoud T (1997) Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell esophageal cancer. Eur J Cancer 33: 1216-1220
-
(1997)
Eur J Cancer
, vol.33
, pp. 1216-1220
-
-
Bleiberg, H.1
Conroy, T.2
Paillot, B.3
Lacave, A.J.4
Blijham, G.5
Jacob, J.H.6
Bedenne, L.7
Namer, M.8
De Besi, P.9
Gay, F.10
Collette, L.11
Sahmoud, T.12
-
2
-
-
0026028040
-
Rising incidence of adenocarcinoma of the esophagus and gastric cardia
-
Blot WJ, Devesa SS, Kneller RW, Fraumeni Jr JF (1991) Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 265: 1287-1289
-
(1991)
JAMA
, vol.265
, pp. 1287-1289
-
-
Blot, W.J.1
Devesa, S.S.2
Kneller, R.W.3
Fraumeni Jr., J.F.4
-
3
-
-
0033050165
-
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
-
Blum JL, Jones SE, Buzdar AU, LoRusso PM, Kuter I, Vogel C, Osterwalder B, Burger HU, Brown CS, Griffin T (1999) Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol 17:485-493
-
(1999)
J Clin Oncol
, vol.17
, pp. 485-493
-
-
Blum, J.L.1
Jones, S.E.2
Buzdar, A.U.3
Lorusso, P.M.4
Kuter, I.5
Vogel, C.6
Osterwalder, B.7
Burger, H.U.8
Brown, C.S.9
Griffin, T.10
-
4
-
-
9044224771
-
Phase II trial of vinorelbine in metastatic squamous cell carcinoma
-
European Organization for Research and Treatment of Cancer Gastrointestinal Treat Cancer Cooperative Group
-
Conroy T, Etienne PL, Adenis A, Wagener DJT, Paillot B, Francois E, Bedenne L, Jacob JH, Seitz JF, Bleiberg H, Van Pottelsberghe C, Van Glabbeke M, Delgado FM, Merle S, Wils J (1996) Phase II trial of vinorelbine in metastatic squamous cell carcinoma. European Organization for Research and Treatment of Cancer Gastrointestinal Treat Cancer Cooperative Group. J Clin Oncol 14: 164-167
-
(1996)
J Clin Oncol
, vol.14
, pp. 164-167
-
-
Conroy, T.1
Etienne, P.L.2
Adenis, A.3
Wagener, D.J.T.4
Paillot, B.5
Francois, E.6
Bedenne, L.7
Jacob, J.H.8
Seitz, J.F.9
Bleiberg, H.10
Van Pottelsberghe, C.11
Van Glabbeke, M.12
Delgado, F.M.13
Merle, S.14
Wils, J.15
-
5
-
-
0030451795
-
Phase II trial of docetaxel (Taxotere) in patients with adenocarcinomas of the upper gastrointestinal tract previously untreated with cytotoxic chemotherapy: The Eastern Cooperative Oncology Group (ECOG) results of the protocol E1293
-
Einzig AI, Neuberg D, Remick SC, Karp DD, O'Dwyer PJ, Stewart JA, Benson III AB (1996) Phase II trial of docetaxel (Taxotere) in patients with adenocarcinomas of the upper gastrointestinal tract previously untreated with cytotoxic chemotherapy: the Eastern Cooperative Oncology Group (ECOG) results of the protocol E1293. Med Oncol 13: 87-93
-
(1996)
Med Oncol
, vol.13
, pp. 87-93
-
-
Einzig, A.I.1
Neuberg, D.2
Remick, S.C.3
Karp, D.D.4
O'Dwyer, P.J.5
Stewart, J.A.6
Benson III, A.B.7
-
7
-
-
50549174560
-
The determination of the number of patients required in a preliminary and a follow-up trials of a new chemotherapeutic agent
-
Gehan EA (1961) The determination of the number of patients required in a preliminary and a follow-up trials of a new chemotherapeutic agent. J Chronic Dis 13: 346-353
-
(1961)
J Chronic Dis
, vol.13
, pp. 346-353
-
-
Gehan, E.A.1
-
8
-
-
20244364497
-
Phase II evaluation of protracted infusion of cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the esophagus: A Japanese Esophageal Oncology Group (JEOG) Trial (JCOG9407)
-
Hayashi K, Ando N, Watanabe H, Ide H, Nagai K, Aoyama N, Takiyama W, Ishida K, Isono K, Makuuchi H, Imamura M, Shinoda M, Ikeuchi S, Kabuto T, Yamana H, Fukuda H (2001) Phase II evaluation of protracted infusion of cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the esophagus: a Japanese Esophageal Oncology Group (JEOG) Trial (JCOG9407). Jpn J Clin Oncol 31: 419-423
-
(2001)
Jpn J Clin Oncol
, vol.31
, pp. 419-423
-
-
Hayashi, K.1
Ando, N.2
Watanabe, H.3
Ide, H.4
Nagai, K.5
Aoyama, N.6
Takiyama, W.7
Ishida, K.8
Isono, K.9
Makuuchi, H.10
Imamura, M.11
Shinoda, M.12
Ikeuchi, S.13
Kabuto, T.14
Yamana, H.15
Fukuda, H.16
-
9
-
-
0036203194
-
Phase II trial of docetaxel chemotherapy in patients with incurable adenocarcinoma of the esophagus
-
Heath EI, Urba S, Marshall J, Piantadosi S, Forastiere AA (2002) Phase II trial of docetaxel chemotherapy in patients with incurable adenocarcinoma of the esophagus. Invest New Drugs 20: 95-99
-
(2002)
Invest New Drugs
, vol.20
, pp. 95-99
-
-
Heath, E.I.1
Urba, S.2
Marshall, J.3
Piantadosi, S.4
Forastiere, A.A.5
-
10
-
-
0035871538
-
Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: Results of a randomized phase III study
-
Hoff PM, Ansari G, Batist G, Cox J, Kocha W, Kuperminc M, Maroun J, Walde D, Weaver C, Harrison E, Burger HU, Osterwalder B, Wong AO, Wong R (2001) Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol 19: 2282-2292
-
(2001)
J Clin Oncol
, vol.19
, pp. 2282-2292
-
-
Hoff, P.M.1
Ansari, G.2
Batist, G.3
Cox, J.4
Kocha, W.5
Kuperminc, M.6
Maroun, J.7
Walde, D.8
Weaver, C.9
Harrison, E.10
Burger, H.U.11
Osterwalder, B.12
Wong, A.O.13
Wong, R.14
-
11
-
-
0026871235
-
Phase II evaluation of cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the esophagus: A Japanese Esophageal Oncology Group Trial
-
Iizuka T, Kakegawa T, Ide H, Ando N, Watanabe H, Tanaka O, Takagi I, Isono K, Ishida K, Arimori M (1992) Phase II evaluation of cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the esophagus: a Japanese Esophageal Oncology Group Trial. Jpn J Clin Oncol 22: 172-176
-
(1992)
Jpn J Clin Oncol
, vol.22
, pp. 172-176
-
-
Iizuka, T.1
Kakegawa, T.2
Ide, H.3
Ando, N.4
Watanabe, H.5
Tanaka, O.6
Takagi, I.7
Isono, K.8
Ishida, K.9
Arimori, M.10
-
12
-
-
0031831196
-
Phase II trial of paclitaxel, fluorouracil, and cisplatin in patients with advanced carcinoma of the esophagus
-
Ilson DH, Ajani J, Bhalla K, Forastiere A, Huang Y, Patel P, Martin L, Donegan J, Pazdur R, Reed C, Kelsen DP (1998) Phase II trial of paclitaxel, fluorouracil, and cisplatin in patients with advanced carcinoma of the esophagus. J Clin Oncol 16: 1826-1834
-
(1998)
J Clin Oncol
, vol.16
, pp. 1826-1834
-
-
Ilson, D.H.1
Ajani, J.2
Bhalla, K.3
Forastiere, A.4
Huang, Y.5
Patel, P.6
Martin, L.7
Donegan, J.8
Pazdur, R.9
Reed, C.10
Kelsen, D.P.11
-
13
-
-
0032887574
-
Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancer
-
Ilson DH, Saltz L, Enzinger P, Huang Y, Kornblith A, Gollub M, O'Reilly E, Schwartz G, De Groff J, Gonzales G, Kelsen DP (1999) Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancer. J Clin Oncol 17: 3270-3275
-
(1999)
J Clin Oncol
, vol.17
, pp. 3270-3275
-
-
Ilson, D.H.1
Saltz, L.2
Enzinger, P.3
Huang, Y.4
Kornblith, A.5
Gollub, M.6
O'Reilly, E.7
Schwartz, G.8
De Groff, J.9
Gonzales, G.10
Kelsen, D.P.11
-
14
-
-
0033770113
-
Capecitabine: Preclinical pharmacology studies
-
Ishitsuka H (2000) Capecitabine: preclinical pharmacology studies. Invest New Drugs 18: 343-354
-
(2000)
Invest New Drugs
, vol.18
, pp. 343-354
-
-
Ishitsuka, H.1
-
15
-
-
24044474479
-
A phase II study of paclitaxel and capecitabine combination chemotherapy in patients with advanced gastric cancer as a first-line therapy
-
abstr 4051
-
Kang HJ, Kim TW, Chang HM, Ryu M-H, Yook JH, Oh ST, Kim BS, Lee JS, Kim WK, Kang Y-K (2004) A phase II study of paclitaxel and capecitabine combination chemotherapy in patients with advanced gastric cancer as a first-line therapy. Proc Am Soc Clin Oncol 23: 325 (abstr 4051)
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
, pp. 325
-
-
Kang, H.J.1
Kim, T.W.2
Chang, H.M.3
Ryu, M.-H.4
Yook, J.H.5
Oh, S.T.6
Kim, B.S.7
Lee, J.S.8
Kim, W.K.9
Kang, Y.-K.10
-
16
-
-
18544366040
-
A phase II study of weekly docetaxel and capecitabine in patients with metastatic gastric cancer
-
abstr 4057
-
Kim HK, Chun JH, Lee JY, Choi HG, Lee HG, Choi IJ, Ryu KW, Kim Y-W, Lee JS, Bae J-M (2004) A phase II study of weekly docetaxel and capecitabine in patients with metastatic gastric cancer. Proc Am Soc Clin Oncol 23: 326 (abstr 4057)
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
, pp. 326
-
-
Kim, H.K.1
Chun, J.H.2
Lee, J.Y.3
Choi, H.G.4
Lee, H.G.5
Choi, I.J.6
Ryu, K.W.7
Kim, Y.-W.8
Lee, J.S.9
Bae, J.-M.10
-
17
-
-
0041733716
-
Phase II trial of irinotecan plus docetaxel in cisplatin-pretreated relapsed or refractory oesophageal cancer
-
Lordick F, von Schilling C, Bernhard H, Hennig M, Bredenkamp R, Peschel C (2003) Phase II trial of irinotecan plus docetaxel in cisplatin-pretreated relapsed or refractory oesophageal cancer. Br J Cancer 89: 630-633
-
(2003)
Br J Cancer
, vol.89
, pp. 630-633
-
-
Lordick, F.1
Von Schilling, C.2
Bernhard, H.3
Hennig, M.4
Bredenkamp, R.5
Peschel, C.6
-
18
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
-
Miwa M, Ura M, Nishida M, Rocha PR, Rodrigues MA, Rausch M (1998) Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 34: 1274-1281
-
(1998)
Eur J Cancer
, vol.34
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Rocha, P.R.4
Rodrigues, M.A.5
Rausch, M.6
-
19
-
-
3442902880
-
A phase II study of single-agent docetaxel in patients with metastatic oesophageal cancer
-
Muro K, Hamaguchi T, Ohtsu A, Boku N, Chin K, Hyodo I, Fujita H, Takiyama W, Ohtsu T (2004) A phase II study of single-agent docetaxel in patients with metastatic oesophageal cancer. Ann Oncol 15: 955-959
-
(2004)
Ann Oncol
, vol.15
, pp. 955-959
-
-
Muro, K.1
Hamaguchi, T.2
Ohtsu, A.3
Boku, N.4
Chin, K.5
Hyodo, I.6
Fujita, H.7
Takiyama, W.8
Ohtsu, T.9
-
20
-
-
0037096755
-
Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results
-
O'Shaughnessy J, Miles D, Vukelja S, Moiseyenko V, Ayoub JP, Cervantes G, Fumoleau P, Jones S, Lui WY, Mauriac L, Twelves C, Van Hazel G, Verma S, Leonard R (2002) Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results. J Clin Oncol 20: 2812-2823
-
(2002)
J Clin Oncol
, vol.20
, pp. 2812-2823
-
-
O'Shaughnessy, J.1
Miles, D.2
Vukelja, S.3
Moiseyenko, V.4
Ayoub, J.P.5
Cervantes, G.6
Fumoleau, P.7
Jones, S.8
Lui, W.Y.9
Mauriac, L.10
Twelves, C.11
Van Hazel, G.12
Verma, S.13
Leonard, R.14
-
21
-
-
0031944611
-
Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by Taxol/Taxotere in human xenografts
-
Sawada N, Ishikawa T, Fukase Y, Nishida M, Yoshikubo T, Ishitsuka H (1998) Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by Taxol/Taxotere in human xenografts. Clin Cancer Res 4: 1013-1019
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1013-1019
-
-
Sawada, N.1
Ishikawa, T.2
Fukase, Y.3
Nishida, M.4
Yoshikubo, T.5
Ishitsuka, H.6
-
22
-
-
9144238357
-
Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: Safety results of a randomized, phase III trial
-
Scheithauer W, McKendrick J, Begbie S, Borner M, Burns WI, Burris HA, Cassidy J, Jodrell D, Koralewski P, Levine EL, Marschner N, Maroun J, Garcia-Alfonso P, Tujakowski J, Van Hazel G, Wong A, Zaluski J, Twelves C, for the X-ACT Study Group (2003) Oral capecitabine as an alternative to i.v. 5-fluorouracil-based adjuvant therapy for colon cancer: safety results of a randomized, phase III trial. Ann Oncol 14: 1735-1743
-
(2003)
Ann Oncol
, vol.14
, pp. 1735-1743
-
-
Scheithauer, W.1
McKendrick, J.2
Begbie, S.3
Borner, M.4
Burns, W.I.5
Burris, H.A.6
Cassidy, J.7
Jodrell, D.8
Koralewski, P.9
Levine, E.L.10
Marschner, N.11
Maroun, J.12
Garcia-Alfonso, P.13
Tujakowski, J.14
Van Hazel, G.15
Wong, A.16
Zaluski, J.17
Twelves, C.18
-
23
-
-
0034016415
-
Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients
-
Schuller J, Cassidy J, Dumont E, Roos B, Durston S, Banken L, Utoh M, Mori K, Weiderkamm E, Reigner B (2000) Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients. Cancer Chemother Pharmacol 45: 291-297
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, pp. 291-297
-
-
Schuller, J.1
Cassidy, J.2
Dumont, E.3
Roos, B.4
Durston, S.5
Banken, L.6
Utoh, M.7
Mori, K.8
Weiderkamm, E.9
Reigner, B.10
-
24
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumours
-
European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, Van Glabbeke M, van Oosterom AT, Christian MC, Gwyther SF (2000) New guidelines to evaluate the response to treatment in solid tumours. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92: 205-216
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
Wanders, J.4
Kaplan, R.S.5
Rubinstein, L.6
Verweij, J.7
Van Glabbeke, M.8
Van Oosterom, A.T.9
Christian, M.C.10
Gwyther, S.F.11
-
25
-
-
0034016343
-
Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: Results of a randomized phase II study
-
Van Cutsem E, Findlay M, Osterwalder B, Kocha W, Dalley D, Pazdur R, Cassidy J, Dirix L, Twelves C, Allman D, Seitz JF, Scholmerich J, Burger HU, Verweij J (2000) Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study. J Clin Oncol 18: 1337-1345
-
(2000)
J Clin Oncol
, vol.18
, pp. 1337-1345
-
-
Van Cutsem, E.1
Findlay, M.2
Osterwalder, B.3
Kocha, W.4
Dalley, D.5
Pazdur, R.6
Cassidy, J.7
Dirix, L.8
Twelves, C.9
Allman, D.10
Seitz, J.F.11
Scholmerich, J.12
Burger, H.U.13
Verweij, J.14
-
26
-
-
11144354462
-
Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: Integrated efficacy data and novel analyses from two large, randomized, phase III trials
-
Van Cutsem E, Hoff PM, Harper P, Bukowski RM, Cunningham D, Dufour P, Graeven U, Lokich J, Madajewicz S, Maroun JA, Marshall JL, Mitchell EP, Perez-Manga G, Rougier P, Schmiegel W, Schoelmerich J, Sobrero A, Schilsky RL (2004) Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomized, phase III trials. Br J Cancer 90: 1190-1197
-
(2004)
Br J Cancer
, vol.90
, pp. 1190-1197
-
-
Van Cutsem, E.1
Hoff, P.M.2
Harper, P.3
Bukowski, R.M.4
Cunningham, D.5
Dufour, P.6
Graeven, U.7
Lokich, J.8
Madajewicz, S.9
Maroun, J.A.10
Marshall, J.L.11
Mitchell, E.P.12
Perez-Manga, G.13
Rougier, P.14
Schmiegel, W.15
Schoelmerich, J.16
Sobrero, A.17
Schilsky, R.L.18
-
27
-
-
0035503151
-
Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
-
Van Cutsem E, Twelves C, Cassidy J, Allman D, Bajetta E, Boyer M, Bugat R, Findlay M, Frings S, Jahn M, McKendrick J, Osterwalder B, Perez-Manga G, Rosso R, Rougier P, Schmiegel WH, Seitz JF, Thompson P, Vieitez JM, Weitzel C, Harper P, Xeloda Colorectal Cancer Study Group (2001) Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol 19: 4097-4106
-
(2001)
J Clin Oncol
, vol.19
, pp. 4097-4106
-
-
Van Cutsem, E.1
Twelves, C.2
Cassidy, J.3
Allman, D.4
Bajetta, E.5
Boyer, M.6
Bugat, R.7
Findlay, M.8
Frings, S.9
Jahn, M.10
McKendrick, J.11
Osterwalder, B.12
Perez-Manga, G.13
Rosso, R.14
Rougier, P.15
Schmiegel, W.H.16
Seitz, J.F.17
Thompson, P.18
Vieitez, J.M.19
Weitzel, C.20
Harper, P.21
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