The Tropical Biominer Project: Mining old sources for new drugs

OMICS A Journal of Integrative Biology

Volumn 9, Issue 2, 2005, Pages 130-138

  Artiguenave, François ^b,c   Lins, André ^a   Maciel, Wesley Dias ^a   Caldeira Jr , Antonio Celso ^a   Nacif Coelho, Carla ^c   De Souza Linhares, Maria Margarida Ribeiro ^c   De Oliveira, Guilherme Correa ^b   Barbosa, Luis Humberto Rezende ^a   Lopes, Júlio César Dias ^a   Coelho Jr , Claudionor Nunes ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c Homologix   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

INDIRUBIN; INDIRUBIN 3 MONOXIME; INDIRUBIN 5 SULFONATE; NATURAL PRODUCT; NEW DRUG; PLANT EXTRACT; UNCLASSIFIED DRUG; VIOLACEIN;

ALGORITHM; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROTOZOAL ACTIVITY; BIOTECHNOLOGY; BRAZIL; CHEMOGENOMICS; CHROMOBACTERIUM; COMPUTER PROGRAM; DATA BASE; DRUG RESEARCH; DRUG SCREENING; GENOMICS; INFORMATION PROCESSING; INTERNET; LEISHMANIA; PARASITOSIS; PRIORITY JOURNAL; PROTEOMICS; REVIEW; TRYPANOSOMA CRUZI; VIRTUAL REALITY;

ANIMALS; ANTIPARASITIC AGENTS; BRAZIL; DATABASES, FACTUAL; DRUG EVALUATION, PRECLINICAL; FOUNDATIONS; HUMANS; PARASITIC DISEASES; USER-COMPUTER INTERFACE;

EID: 22044447947     PISSN: 15362310     EISSN: None     Source Type: Journal    
DOI: 10.1089/omi.2005.9.130     Document Type: Review

References (20)

1. AMIT, P., and JAMES, A.L. (1990). Federated database systems for managing distributed, heterogeneous, and autonomous databases. ACM Comput Surv 22, 183-236.
2. ANTONIO, R.V., and CRECZYNSKI-PASA, T.B. (2004). Genetic analysis of violacein biosynthesis by Chromobacterium violaceum. Genet Mol Res 31, 85-91.
3. BERTRAND, J.A., THIEFFINE, S., VULPETTI, A., et al. (2003). Structural characterization of the GSK-3β active site using selective and non-selective ATP-mimetic inhibitors. J Mol Biol 333, 393-407.
4. BROMBERG, N., and DURAN, N. (2001). Violacein biotransformation by basidiomycetes and bacteria. Lett Appl Microbiol 33, 316-319.
5. CSIZMADIA, F. (2000). JChem: Java applets and modules supporting chemical database handling from web browsers. J Chem Inf Comput Sci 40, 323-324.
6. DALBY, A., NOURSE, J.G., HOUNSHELL, W.D., et al. (1992). Description of several chemical-structure file formats used by computer-programs developed at Molecular Design Limited. J Chem Inf Comput Sci 32, 244-255.
7. DISCALA, C., BENIGNI, X., BARILLOT, B., et al. (2000). DBcat: a catalog of 500 biological databases. Nucleic Acids Res 28, 8-9.
8. DURAN, N., and MENCK, C.F.M. (2001). Chromobacterium violaceum: a review of pharmacological and industrial perspective. Crit Rev Microbiol 27, 201-222.
9. EISENBRAND, G., HIPPE, F., JAKOBS, S., et al. (2004). Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine. J Cancer Res Clin Oncol 130, 627-635.
10. FILIMONOV, D.A., and POROIKOV, V.V. (1996). PASS: computerized prediction of biological activity spectra for chemical substances. In Bioactive Compound Design: Possibilities for Industrial Use. Eds: M.G. Ford, R. Greenwood, G.T. Brooks, and R. Franke (BIOS Scientific Publishers, Oxford), pp. 47-56.
11. HAMMER, M., and MCLEOD, D. (1979). On database management system architecture. Technical Response MIT/LCS/TM-141. Massachusetts Institute of Technology, Cambridge.
12. HEIMBIGNER, D., and MCLEOD, D. (1985). A federated architecture for information management. ACM Trans Off Syst 3, 253-278.
13. LEON, L.L., MIRANDA, C.C., DE SOUZA, A.O., et al. (2001). Anti-leishmanial activity of the violacein extracted from Chromobacterium violaceum. Antimicrob Agents Chemother 48, 449-450.
14. MELO, P.S., MARIA, S.S., VIDAL, B.C., et al. (2000). Violacein cytotoxicity and induction of apoptosis in V79 cells. In Vitro Cell Dev Biol Anim 36, 539-543.
15. MILNE, G.W.A., NICKLAUS, M.C., DRISCOLL, J.S., et al. (1994). National Cancer Institute drug information system 3D database. J Chem Inf Comput Sci 34, 1219-1224.
16. MONKS, A.P., SCUDIERO, D.A., JOHNSON, G.S., et al. (1997). The NCI anti-cancer drug screen: a smart screen to identify effectors of novel targets. Anticancer Drug Des 12, 533-541.
17. SCHREIBER, S. (2004). Stuart Schreiber: biology from a chemist's perspective. Interview by Joanna Owens. Drug Discov Today 9, 299-303.
18. SCHUFFENHAUER, A., and JACOBY, E. (2004). Annotating and mining the ligand-target chemogenomics knowledge space. Drug Discov Today 2, 190-200.
19. VOIGT, J.H., BIENFAIT, B., WANG, S., et al. (2001). Comparison of the NCI Open Database with seven large chemical structural databases. J Chem Inf Comput Sci 41, 702-712.
20. WASZKOWYCZ, B., PERKINS, D.J., SYKES, R.A., et al. (2001). Large-scale virtual screening for discovering leads in the post-genomic era. IBM Syst J 40, 360-376.