Effects of glucose and α-tocopherol on low-density lipoprotein oxidation and glycation

Annals of the New York Academy of Sciences

Volumn 1042, Issue , 2005, Pages 294-302

  Chang, Chun Jen ^a   Hsieh, Rong Hong ^b   Wang, Hui Fang ^b   Chin, Mei Yun ^b   Huang, Shih Yi ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Glucose; Glycation; LDL; Oxidation; tocopherol

Indexed keywords

ALPHA TOCOPHEROL; COPPER; GLUCOSE; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANTIOXIDANT ACTIVITY; CONFERENCE PAPER; DIABETES MELLITUS; DRUG EFFICACY; GLYCATION; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; IN VITRO STUDY; LIPID OXIDATION; LIPOPROTEIN METABOLISM; OXIDATIVE STRESS;

EID: 22044433189     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1338.052     Document Type: Conference Paper

References (27)

1. KÄNNEL, W.B. & D.L. MCGEE. 1979. Diabetes and cardiovascular disease. The Framingham study. JAMA 241: 2035-2038.
2. PYORALA, K., M. LAAKSO. & M. UUSITUPA. 1987. Diabetes and atherosclerosis: an epidemiologic view. Diabetes 3: 463-524.
3. BIERMAN, E.L. 1992. Atherogenesis in diabetes. Arterioscler. Thromb. 12: 647-656.
4. CHAKRABARTI, S., M. CUKIERNIK, D. HILEETO, et al. 2000. Role of vasoactive factors in the pathogenesis of early changes in diabetic retinopathy. Diabetes Metab. Res. Rev. 16: 393-407.
5. LYONS, T.J. 1993. Glycation and oxidation: a role in the pathogenesis of atherosclerosis. Am. J. Cardiol. 71: 26B-31B.
6. BROWNLEE, M. 1996. Advanced glycation endproducts in diabetic complications. Curr. Opin. Endocrinol. Diabetes 3: 291-297.
7. JAKUŠ, V. & N. RIETBROCK. 2004. Advanced glycation end-products and the progress of diabetic vascular complications. Physiol. Res. 53: 131-142.
8. LYONS, T. & A.J. JENKINS. 1997. Glycation, oxidation and lipoxidation in the development of the complications of diabetes mellitus: a carbonyl stress hypothesis. Diabetes Rev. 5: 365-391.
9. OOKAWARA, T., N. KAWAMURA, Y. KITAGAWA & N. TANIGUCHI. 1992. Site-specific and random fragmentation of Cu,Zn-superoxide dismutase by glycation reaction. J. Biol. Chem. 267: 18505-18510.
10. ε-(carboxymethyl)lysine formation from Amadori products. Biochem. Biophys. Res. Commun. 234: 167-172.
11. KAWAMURA, M., N. HEINECKE & A. CHAIT. 1994. Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway. J. Clin. Invest. 94: 771-778.
12. VLASSARA, H., M. BROWNLEE. & A. CERAMI. 1986. Nonenzymatic glycosylation: role in the pathogenesis of diabetic complications. Clin. Chem. 32: B37-B41.
13. WITZTUM, J.L. & D. STEINBERG. 1991. Role of ox-LDL in atherogenesis. J. Clin. Invest. 88: 1785-1792.
14. VIANA, M., C. BARBAS, B. BONET, et al. 1996. In vitro effects of a flavonoid-rich extract on LDL oxidation. Atherosclerosis 123: 83-91.
15. ESTERBAUER, H., M. DIEBER-ROTHENEDER, G. STRIEGL & G. WAEG. 1991. Role of vitamin E in preventing the oxidation of low-density lipoprotein. Am. J. Clin. Nutr. 53: 3145-3215.
16. JAIN, S.K. & M. PALMER. 1997. The effect of oxygen radical metabolities and vitamin E on glycosylation of proteins. Free Radic. Biol. Med. 22: 593-596.
17. JIALAL, I., C.J. FULLER & B.A. HUET. 1995. The effect of α-tocopherol supplementation on LDL oxidation. A dose-response study. Atheroscler. Thromb. Vasc. Biol. 15: 190-198.
18. MANI, I., J. PATEL & U.V. MANI. 1987. Measurement of serum glycosylated proteins and glycosylated low density lipoprotein fraction in diabetes mellitus. Biochem. Med. Metab. Biol. 37: 184-189.
19. ARNAUD, J., I. FORTIS, S. BLACHIER, et al. 1991. Simultaneous determination of retinol, α-tocopherol and β-carotene in serum by isocratic high-performance liquid chromatography. J. Chromatogr. 572: 103-116.
20. YOUNG, I.S., J.J. TORNEY & E.R. TRIMBLE. 1992. The effect of ascorbate supplementation on oxidative stress in the streptozotocin diabetic rat. Free Radic. Biol. Med. 13: 41-46.
21. OHKUWA, T., Y. SATO & M. NAIO. 1995. Hydroxyl radical formation in diabetic rats induced by streptozotocin. Life Sci. 56: 1789-1798.
22. HUNT, J.V., M.A. BOTTOMS, K. CLARE, et al. 1994. Glucose oxidation and low-density lipoprotein-induced macrophage ceroid accumulation: possible implications for diabetic atherosclerosis. Biochem. J. 300: 243-249.
23. MORO, E., P. ALESSANDRINI, C. ZAMBON, et al. 1999. Is glycation of low density lipoproteins in patients with type 2 diabetes mellitus a LDL pre-oxidative condition? Diabet. Med. 16: 663-669.
24. AVOGARO, P., G. CAZZOLATO & G. BITTOLO-BON. 1991. Some questions concerning a small, more electronegative LDL circulating in human plasma. Atherosclerosis 91: 163-171.
25. HAIDARI, M., E. JAVADI, M. KADKHODAEE & A. SANATI. 2001. Enhanced susceptibility to oxidation and diminished vitamin E content of LDL from patients with stable coronary artery disease. Clin. Chem. 47: 1234-1240.
26. PRONAI, L., K. HIRAMATSU, Y. SAIGUSA & H. NAKAZAWA. 1991. Low superoxide scavenging activity associated with enhanced superoxide generation by monocytes from male hypertriglyceridemia with and without diabetes. Atherosclerosis 90: 39-47.
27. MULLARKEY, C.J., D. EDELSTEIN & M. BROWN. 1990. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem. Biophys. Res. Commun. 173: 932-939.