Unfolding and breakdown of insulin in the presence of endogenous thiols

FEBS Letters

Volumn 579, Issue 18, 2005, Pages 3927-3931

  Jiang, Chuantao ^a   Chang, Jui Yoa ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Insulin; Isomerization of insulin; Stability of insulin; Structure of denatured insulin; Thermal denaturation of insulin; Unfolding of insulin

Indexed keywords

CYSTEINE; DISULFIDE; GUANIDINE; INSULIN; THIOL DERIVATIVE; UREA;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION KINETICS; COMPARATIVE STUDY; DECOMPOSITION; DENATURATION; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN STABILITY; TEMPERATURE;

ANIMALS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; DISULFIDES; GUANIDINE; HEAT; HUMANS; HYDROGEN-ION CONCENTRATION; INSULIN; KINETICS; MASS SPECTROMETRY; MOLECULAR CONFORMATION; PANCREAS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; SULFHYDRYL COMPOUNDS; TEMPERATURE; TIME FACTORS;

EID: 21844479265     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.06.010     Document Type: Article

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