Regional differences in trabecular BMD and micro-architecture of weight-bearing bone under habitual gait loading - A pQCT and microCT study in human cadavers

Bone

Volumn 37, Issue 2, 2005, Pages 274-282

  Lai, Y M ^a,b   Qin, L ^b   Yeung, H Y ^b   Lee, K K H ^b   Chan, K M ^b  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Bone adaptation; Human cadaver; MicroCT; pQCT; Trabecular bone

Indexed keywords

ADULT; AGED; ANISOTROPY; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE MARROW; BONE STRUCTURE; CADAVER; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION COEFFICIENT; FEMALE; FEMUR NECK; GAIT; HUMAN; HUMAN TISSUE; MALE; STATISTICAL SIGNIFICANCE; TIBIA; TISSUE LEVEL; TRABECULAR BONE; VOLUMETRY; WEIGHT BEARING;

AGED; BONE DENSITY; CADAVER; DENSITOMETRY, X-RAY; FEMALE; FEMUR; HUMANS; MALE; MIDDLE AGED; TIBIA; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT-BEARING;

EID: 21844437084     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.04.025     Document Type: Article

References (45)

1. E.J. Bassey, and S.J. Ramsdale Increase in femoral bone density in young women following high-impact exercise Osteoporos. Int. 4 1994 72 75
2. R.D. Bloebaum, J.G. Skedros, E.G. Vajda, K.N. Bachus, and B.R. Constantz Determining mineral content variations in bone using backscattered electron imaging Bone 20 1997 485 490
3. P.D. Chilibeck, D.G. Sale, and C.E. Webber Exercise and bone mineral density Sports Med. 19 1995 103 122
4. S.C. Cowin, A.M. Sadegh, and G.M. Luo An evolutionary Wolff's law for trabecular architecture J. Biomech. Eng. 114 1992 129 136
5. V. David, N. Laroche, B. Boudignon, M.H. Lafage-Proust, C. Alexandre, and P. Ruegsegger Noninvasive in vivo monitoring of bone architecture alterations in hindlimb-unloaded female rats using novel three-dimensional microcomputed tomography J. Bone Miner. Res. 18 2003 1622 1631
6. P.D. Delmas Do we need to change the WHO definition of osteoporosis Osteoporos. Int. 11 2000 189 191
7. D.W. Dempster The contribution of trabecular architecture to cancellous bone quality J. Bone Miner. Res. 15 2000 20 23
8. J.C. Fox, and T.M. Keaveny Trabecular eccentricity and bone adaptation J. Theor. Biol. 212 2001 211 221
9. H.M. Frost Skeletal structural adaptations to mechanical usage (SATMU): 1. Redefining Wolff's law: the bone modeling problem Anat. Rec. 226 1990 403 413
10. S.A. Goldstein, R. Goulet, and D. McCubbrey Measurement and significance of three-dimensional architecture to the mechanical integrity of trabecular bone Calcif. Tissue Int. 53 1993 S127 S132 [discussion S132-3]
11. T. Hara, E. Tanck, J. Homminga, and R. Huiskes The influence of microcomputed tomography threshold variations on the assessment of structural and mechanical trabecular bone properties Bone 31 2002 107 109
12. W.C. Hayes, and M.L. Bouxsein Biomechanics of cortical and trabecular bone: implications for assessment of fracture risk V.C. Mow W.C. Hayes Basic orthopaedic biomechanics 1997 Lippincott-Raven New York 69 111
13. T. Hildebrand, A. Laib, R. Muller, J. Dequeker, and P. Ruegsegger Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus J. Bone Miner. Res. 14 1999 1167 1174
14. T. Hildebrand, and P. Ruegsegger Quantification of bone microarchitecture with the structure model index Comput. Methods Biomech. Biomed. Eng. 1 1997 15 23
15. I. Hvid, O. Rasmussen, N.C. Jensen, and S. Nielsen Trabecular bone strength profiles at the ankle joint Clin. Orthop. 1985 306 312
16. T.L. Jarvinen, P. Kannus, and H. Sievanen Have the DXA-based exercise studies seriously underestimated the effects of mechanical loading on bone? J. Bone Miner. Res. 14 1999 1634 1635
17. Y. Jiang, J. Zhao, P. Augat, X. Ouyang, Y. Lu, and S. Majumdar Trabecular bone mineral and calculated structure of human bone specimens scanned by peripheral quantitative computed tomography: relation to biomechanical properties J. Bone Miner. Res. 13 1998 1783 1790
18. Y. Jiang, J.J. Zhao, B.H. Mitlak, O. Wang, H.K. Genant, and E.F. Eriksen Recombinant human parathyroid hormone (1-34) [teriparatide] improves both cortical and cancellous bone structure J. Bone Miner. Res. 18 2003 1932 1941
19. Y.I. Joo, T. Sone, M. Fukunaga, S.G. Lim, and S. Onodera Effects of endurance exercise on three-dimensional trabecular bone microarchitecture in young growing rats Bone 33 2003 485 493
20. W.M. Kohrt, A.A. Ehsani, and S.J. Birge Jr. Effects of exercise involving predominantly either joint-reaction or ground-reaction forces on bone mineral density in older women J. Bone Miner. Res. 12 1997 1253 1261
21. Y.M. Lai, L. Qin, V.W.Y. Hung, and K.M. Chan Regional differences in cortical bone mineral density differences in the weight-bearing long bone shaft-A pQCT study Bone 36 2005 465 471
22. L.E. Lanyon, and C.T. Rubin Static vs. dynamic loads as an influence on bone remodelling J. Biomech. 17 1984 897 905
23. T.M. Link, S. Majumdar, S. Grampp, G. Guglielmi, C. van Kuijk, and H. Imhof Imaging of trabecular bone structure in osteoporosis Eur. Radiol. 9 1999 1781 1788
24. J.C. Lotz, E.J. Cheal, and W.C. Hayes Stress distributions within the proximal femur during gait and falls: implications for osteoporotic fracture Osteoporos. Int. 5 1995 252 261
25. M.W. Mason, J.G. Skedros, and R.D. Bloebaum Evidence of strain-mode-related cortical adaptation in the diaphysis of the horse radius Bone 17 1995 229 237
26. R. Muller, H. Van Campenhout, B. Van Damme, G. Van Der Perre, J. Dequeker, and T. Hildebrand Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography Bone 23 1998 59 66
27. A.H. Ng, G. Hercz, R. Kandel, and M.D. Grynpas Association between fluoride, magnesium, aluminum and bone quality in renal osteodystrophy Bone 34 2004 216 224
28. M. Nordin, and V.H. Frankel Biomechanics of the hip M. Nordin V.H. Frankel Basic biomechanics of the musculoskeletal system 2001 Lippincott Williams and Wilkins Philadelphia 202 221
29. A. Odgaard, and H.J. Gundersen Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstructions Bone 14 1993 173 182
30. J. Perry Gait analysis: Normal and pathological function 1992 SLACK Thorofare (NJ)
31. L. Qin, S.K. Au, P.C. Leung, M.C. Lau, J. Woo, and W.Y. Choy Baseline BMD and bone loss at distal radius measured by pQCT in Peri- and postmenopausal Hong Kong Chinese women Osteoporos. Int. 13 2002 962 970
32. F. Rauch, and E. Schoenau Changes in bone density during childhood and adolescence: an approach based on bone's biological organization J. Bone Miner. Res. 16 2001 597 604
33. C. Rubin, A.S. Turner, R. Muller, E. Mittra, K. McLeod, and W. Lin Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention J. Bone Miner. Res. 17 2002 349 357
34. P. Ruegsegger The use of peripheral QCT in the evaluation of bone remodelling Endocrinologist 4 1994 167 176
35. P. Ruegsegger, B. Koller, and R. Muller A microtomographic system for the nondestructive evaluation of bone architecture Calcif. Tissue Int. 58 1996 24 29
36. A. Schoutens, E. Laurent, and J.R. Poortmans Effects of inactivity and exercise on bone Sports Med. 7 1989 71 81
37. M. Singh, A.R. Nagrath, and P.S. Maini Changes in trabecular pattern of the upper end of the femur as an index of osteoporosis J. Bone Jt. Surg. Am. 52 1970 457 467
38. M.C. Singleton, and B.F. LeVeau The hip joint: structure, stability, and stress; a review Phys. Ther. 55 1975 957 973
39. W.S. Siu, L. Qin, and K.S. Leung pQCT bone strength index is a better predictor than bone mineral density for long bone breaking strength in goats J. Bone Miner. Metab. 21 2003 316 322
40. J.G. Skedros, M.W. Mason, M.C. Nelson, and R.D. Bloebaum Evidence of structural and material adaptation to specific strain features in cortical bone Anat. Rec. 246 1996 47 63
41. Y. Takano, C.H. Turner, I. Owan, R.B. Martin, S.T. Lau, and M.R. Forwood Elastic anisotropy and collagen orientation of osteonal bone are dependent on the mechanical strain distribution J. Orthop. Res. 17 1999 59 66
42. E. Tanck, J. Homminga, G.H. van Lenthe, and R. Huiskes Increase in bone volume fraction precedes architectural adaptation in growing bone Bone 28 2001 650 654
43. D. Ulrich, B. van Rietbergen, A. Laib, and P. Ruegsegger The ability of three-dimensional structural indices to reflect mechanical aspects of trabecular bone Bone 25 1999 55 60
44. W.J. Whitehouse The quantitative morphology of anisotropic trabecular bone J. Microsc. 101 Pt. 2 1974 153 168
45. I. Wolff, J.J. van Croonenborg, H.C. Kemper, P.J. Kostense, and J.W. Twisk The effect of exercise training programs on bone mass: a meta-analysis of published controlled trials in pre- and postmenopausal women Osteoporos. Int. 9 1999 1 12