Loperamide inhibits tachykinin NK3-receptor-triggered serotonin release without affecting NK2-receptor-triggered serotonin release from guinea pig colonic mucosa

Journal of Pharmacological Sciences

Volumn 98, Issue 2, 2005, Pages 175-180

  Kojima, Shu Ichi ^a   Ikeda, Masashi ^a   Kamikawa, Yuichiro ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Colon; Loperamide; Opioid receptor; Serotonin; Tachykinin

Indexed keywords

BENZOYLALANYLALANYL DEXTRO TRYPTOPHYLPHENYLALANYL DEXTRO PROLYLPROLYLNORLEUCINAMIDE; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; KAPPA OPIATE RECEPTOR; LOPERAMIDE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR ANTAGONIST; N (ALPHA ETHYLBENZYL) 3 METHYL 2 PHENYL 4 QUINOLINECARBOXAMIDE; NALTRINDOLE; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR AGONIST; NEUROKININ 2 RECEPTOR ANTAGONIST; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; NEUROKININ A [4-10][8 BETA ALANINE]; NEUROKININ DERIVATIVE; NORBINALTORPHIMINE; SENKTIDE; SEROTONIN; TACHYKININ RECEPTOR;

ANIMAL TISSUE; ARTICLE; COLON MUCOSA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SENSITIVITY; GUINEA PIG; NONHUMAN; PROTEIN LOCALIZATION; RECEPTOR BLOCKING; SEROTONIN RELEASE;

EID: 21744431981     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.FPJ05011X     Document Type: Article

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