Characterization of opioid receptors modulating neurogenic contractions of circular muscle from porcine ileum and evidence that δ- and κ-opioid receptors are coexpressed in myenteric neurons

Journal of Pharmacology and Experimental Therapeutics

Volumn 297, Issue 1, 2001, Pages 69-77

  Poonyachoti, S ^a   Portoghese, P S ^a   Brown, D R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; ATROPINE; DELTORPHIN; ENKEPHALIN DERIVATIVE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; EPSILON OPIATE RECEPTOR; EPSILON OPIATE RECEPTOR ANTAGONIST; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; LEUCINE ENKEPHALIN[2 DEXTRO SERINE 6 THREONINE]; LOPERAMIDE; MORPHINE; MU OPIATE RECEPTOR AGONIST; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NALTRIBEN; NORBINALTORPHIMINE; OPIATE RECEPTOR; TETRODOTOXIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ELECTROSTIMULATION; FEMALE; ILEUM; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE CONTRACTION; MYENTERIC PLEXUS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE; SWINE;

AMINO ACID SEQUENCE; ANIMALS; ELECTRIC STIMULATION; ENKEPHALIN, LEUCINE; GOATS; ILEUM; MOLECULAR SEQUENCE DATA; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYENTERIC PLEXUS; NALTREXONE; RABBITS; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; SWINE;

EID: 0035078668     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. δ-Opioid receptor immunoreactivity: Distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin
2. Delta-Opioid receptor mRNA expression and immunohistochemical localization in porcine small intestine
3. Opioid peptides in gastrointestinal functions
4. Regulatory role of enteric kappa opioid receptors in human colonic motility
5. Delta-opioid receptor agonists inhibit neuromuscular transmission in human colon
6. Dimerization of the delta opioid receptor: Implication for a role in receptor internalization
7. 3 subtype
8. Insights into opioid action in the intestinal tract
9. Both mu and delta opiate receptors exist on the same neuron
10. Opioid receptor expression in the rat gastrointestinal tract: A quantitative study with comparison to the brain
11. Domain swapping in G-protein coupled receptor dimers
12. Effect of potassium and acetylcholine on canine intestinal smooth muscle
13. Analysis of selective binding epitopes for the kappa-opioid receptor antagonist nor-binaltorphimine
14. G-protein-coupled receptor heterodimerization modulates receptor function
15. Endogenous and exogenous opioids in the control of gastrointestinal motility and secretion
16. Kinetic parameters of narcotic agonists and antagonists, with particular reference to N-allylnoroxymorphone (naloxone)
17. Characterization of opioid receptors in intestinal muscle cells by selective radioligands and receptor protection
18. Endogenous opioid peptides: Multiple agonists and receptors
19. Constipation in advanced cancer patients
20. Investigation of the selectivity of oxymorphone- and naltrexone-derived ligands via site-directed mutagenesis of opioid receptors: Exploring the "address" recognition site
21. The porcine mu-opioid receptor: Molecular cloning and mRNA distribution in lymphoid tissues
22. Pharmacological evidence for a 7-benzylidenenaltrexone-preferring opioid receptor mediating the inhibitory actions of peptidic δ- and μ-opioid agonists on neurogenic ion transport in porcine ileal mucosa
23. A qualitative and quantitative study on the enkephalinergic innervation of the pig gastrointestinal tract
24. Different receptor sites mediate opioid agonism and antagonism
25. Neurohormonal regulation of ion transport in the porcine distal jejunum. Enhancement of sodium and chloride absorption by submucosal opiate receptors
26. The delta-opioid receptor: Molecular pharmacology, signal transduction, and the determination of drug efficacy
27. Human leumorphin is a potent, kappa opioid receptor agonist
28. Isolation and structure of dynorphin, an opioid peptide, from porcine duodenum
29. Selective naltrexone-derived opioid receptor antagonists
30. Functional morphology of the enteric nervous system with special reference to large mammals
31. Involvement of Trp-284, Val-296, and Val-297 of the human delta-opioid receptor in binding of delta-selective ligands
32. Opioid receptor types and subtypes: The delta receptor as a model