Formulation optimization of paclitaxel carried by PEGylated emulsions based on artificial neural network

Pharmaceutical Research

Volumn 21, Issue 9, 2004, Pages 1692-1697

  Fan, Tianyuan ^a   Takayama, Kozo ^b   Hattori, Yoshiyuki ^b   Maitani, Yoshie ^b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b HOSHI UNIVERSITY   (Japan)

Author keywords

Artificial neural network; Emulsions; Optimization; Paclitaxel; PEGylated

Indexed keywords

ALCOHOL; DISTEAROYLPHOSPHATIDYLETHANOLAMINE; MACROGOL 400; MACROGOL DERIVATIVE; NANOPARTICLE; PACLITAXEL; PHOSPHATIDYLETHANOLAMINE; POLYSORBATE 80; SOYBEAN OIL; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

ARTICLE; ARTIFICIAL NEURAL NETWORK; COMPUTER AIDED DESIGN; CONCENTRATION (PARAMETERS); DRUG FORMULATION; DRUG STABILITY; EMULSION; EXPERIMENTAL DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INJECTION; LASER; LIGHT SCATTERING; PARTICLE SIZE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; STORAGE; CHEMISTRY; METHODOLOGY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; EMULSIONS; NEURAL NETWORKS (COMPUTER); PACLITAXEL; PARTICLE SIZE; POLYETHYLENE GLYCOLS;

EID: 21644468970     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000041467.28884.16     Document Type: Article

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