Multi-objective simultaneous optimization based on artificial neural network in a ketoprofen hydrogel formula containing O-ethylmenthol as a percutaneous absorption enhancer

International Journal of Pharmaceutics

Volumn 158, Issue 2, 1997, Pages 203-210

  Takahara, Junichi ^a   Takayama, Kozo ^a   Isowa, Koichi ^b   Nagai, Tsuneji ^a  

^a HOSHI UNIVERSITY   (Japan)

^b Ctr of Japan Biol Chem Co Ltd   (Japan)

Author keywords

Artificial neural networks; Hydrogel; Multi objective simultaneous optimization; O ethylmenthol; Transdermal absorption

Indexed keywords

ALCOHOL; ETHYLMENTHOL; KETOPROFEN; PENETRATION ENHANCING AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ARTIFICIAL NEURAL NETWORK; COMPUTER AIDED DESIGN; COMPUTER PROGRAM; DRUG PENETRATION; DRUG RELEASE; HYDROGEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN ABSORPTION; SKIN IRRITATION;

EID: 0031440251     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00260-3     Document Type: Article

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