Apocynum venetum extract does not induce CYP3A and P-glycoprotein in rats

Biological and Pharmaceutical Bulletin

Volumn 27, Issue 10, 2004, Pages 1649-1652

  Kobayashi, Michiya ^a   Saitoh, Hiroshi ^a   Seo, Shujiro ^b   Butterweck, Veronika ^c   Nishibe, Sansei ^a  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^b Tokiwa Phytochemical Co   (Japan)

^c UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

Apocynum venetum; CYP3A; P glycoprotein; Rat; St John's wort

Indexed keywords

APOCYNUM VENETUM EXTRACT; CYTOCHROME P450 3A; GLYCOPROTEIN P; HYPERICUM PERFORATUM EXTRACT; METHYLPREDNISOLONE; NIFEDIPINE; PLANT EXTRACT; UNCLASSIFIED DRUG; N DEMETHYLASE; UNSPECIFIC MONOOXYGENASE;

ANIMAL EXPERIMENT; APOCYNUM; ARTICLE; BLOOD LEVEL; CHINESE MEDICINE; CONTROLLED STUDY; HYPERICUM PERFORATUM; INTESTINE ABSORPTION; MEDICINAL PLANT; NONHUMAN; RAT; ANIMAL; BIOSYNTHESIS; COMPARATIVE STUDY; HERB DRUG INTERACTION; HYPERICUM; IN VITRO STUDY; MALE; WISTAR RAT;

ANIMALS; APOCYNUM; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP3A; HERB-DRUG INTERACTIONS; HYPERICUM; INTESTINAL ABSORPTION; MALE; METHYLPREDNISOLONE; NIFEDIPINE; OXIDOREDUCTASES, N-DEMETHYLATING; P-GLYCOPROTEIN; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 21644447389     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.27.1649     Document Type: Article

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