Phospholipase A2-dependent effects of the venom from the new guinean small-eyed snake Micropechis ikaheka

Muscle and Nerve

Volumn 32, Issue 1, 2005, Pages 81-87

  Kuruppu, Sanjaya ^a   Isbister, Geoffrey K ^a   Hodgson, Wayne C ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Antivenom; Chick biventer cervicis; Envenoming; Myotoxicity; PLA2

Indexed keywords

4 BROMOPHENACYL BROMIDE; MYOTOXIN; NEUROTOXIN; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; SNAKE VENOM ANTISERUM; TOXIN; TUBOCURARINE CHLORIDE; UNCLASSIFIED DRUG; VENOM; 4-BROMOPHENACYL BROMIDE; ACETOPHENONE DERIVATIVE; ENZYME INHIBITOR; PHOSPHOLIPASE A; SNAKE VENOM; VENOM ANTISERUM;

ANIMAL TISSUE; ARTICLE; CHICKEN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; ENVENOMATION; ENZYME ACTIVITY; GUINEA PIG; HISTOPATHOLOGY; ILEUM; IN VITRO STUDY; MALE; MICROPECHIS IKAHEKA; MUSCLE TWITCH; NERVE; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; SNAKE; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; SMOOTH MUSCLE;

ACETOPHENONES; ANIMALS; ANTIVENINS; CHICKENS; ELAPID VENOMS; ENZYME INHIBITORS; GUINEA PIGS; ILEUM; MALE; MUSCLE, SKELETAL; MUSCLE, SMOOTH; NEUROTOXINS; PHOSPHOLIPASES A;

EID: 21444431975     PISSN: 0148639X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mus.20334     Document Type: Article

References (40)

1. Abe T, Alema S, Miledi R. Isolation and characterization of presynaptically acting neurotoxins from the venom of Bungarus snakes. Eur J Biochem 1977;80:1-12.
2. Barfaraz A, Harvey AL. The use of the chick biventer cervicis preparation to assess the protective activity of six international reference antivenoms on the neuromuscular effects of snake venoms in vitro. Toxicon 1994;32:267-272.
3. Bell KL, Kemp BK, McPherson GA, odgson WC. The smooth muscle relaxant effects of venom from the inland taipan (Oxyuranus microlepidotus). Toxicon 1999;37:229-231.
4. Bell KL, Sutherland SK, Hodgson WC. Some pharmacological studies of venom from the inland taipan (Oxyuranus microlepidotus). Toxicon 1998;36:63-74.
5. Crachi MT, Hammer LW, Hodgson WC. A pharmacological examination of venom from the Papuan taipan (Oxyuranus scutellatus canni). Toxicon 1999;37:1721-1734.
6. Currie BJ. Snakebite in tropical Australia, Papua New Guinea and Irian Jaya. Emerg Med 2000;12:285-294.
7. 2 from the venom of king brown snake, Pseudechis australis, on nerve and muscle. Toxicon 1994;32: 1559-1572.
8. Fohlman J, Eaker D. Isolation and characterization of a lethal myotoxic phospholipase A from the venom of the common sea snake Enhydrina schistosa causing myoglobinuria in mice. Toxicon 1977;15:385-393.
9. 2, MiPLA-1, from Micropechis ikaheka venom. Arch Biochem Biophys 1999;369:181-192.
10. 2 isoenzymes from Micropechis ikaheka venom. Biochim Biophys Acta 2001;1545:30-40.
11. Gavaghan CF, Sparkes G. Delayed myotoxicity in snake envenoming by the tiger snake group. Emerg Med (Fremantle) 2003;15:497-499.
12. 2 and neurotoxic activities in the venom of the New Guinean small-eyed snake (Micropechis ikaheka). Toxicon 1997;35:101-109.
13. Gopalakrishnakone P, Ponraj D, Thwin MM. Myotoxic phospholipases from snake venoms: general myoglobinuric and local myonecrotic toxins. In: Kini RM, editor. Enzymes: structure, function and mechanism. Chichester, UK: John Wiley & Sons, Ltd.; 1997. p 5ll.
14. Gutierrez JM, Ownby CL, Odell GV. Isolation of a myotoxin from Bothrops aspervenom: partial characterization and action on skeletal muscle. Toxicon 1984;22:115-128.
15. Gutierrez JM, Chaves F, Gene JA, Lomonte B, Camacho Z, Schosinsky K. Myonecrosis induced in mice by a basic myotoxin isolated from the venom of the snake Bothrops nummifer (jumping viper) from Costa Rica. Toxicon 1989;27:735-745.
16. Harris JB. Phospholipases in snake venoms and their effects on nerve and muscle. In: Harvey AL, editor. Snake toxins. New York: Pergamon Press; 1991. p 91-129.
17. 2 activity of notexin and its role in muscle damage. Toxicon 1981;19:419-430.
18. Harvey AL, Barfaraz A, Thomson E, Faiz A, Preston S, Harris JB. Screening of snake venoms for neurotoxic and myotoxic effects using simple in vitro preparations from rodents and chicks. Toxicon 1994;32:257-265.
19. Hudson BJ. The small-eyed snake (Micropechis ikaheka): a review of current knowledge. P N G Med J 1988;31:173-178.
20. Hudson BJ, Pomat K. Ten years of snake bite in Madang Province, Papua New Guinea. Trans R Soc Trop Med Hyg 1988;82:506-508.
21. 2. Toxicon 1989;27: 613-635.
22. 2 ammodytoxin and crotoxin bind to distinct high-affinity protein acceptors in Torpedo marmorata electric organ. Biochemistry 1997;36:2779-2787.
23. Murrell G. The effectiveness of the pressure/immobilization first aid technique in the case of a tiger snake bite. Med J Aust 1981;2:295.
24. Nirthanan S, Gao R, Gopalakrishnakone P, Gwee MCE, Khoo HE, Cheah LS, et al. Pharmacological characterization of mikatoxin, an α-neurotoxin isolated from the venom of the New-Guinean small-eyed snake Micropechis ikaheka. Toxicon 2002;40:863-871.
25. Osman OH, Karrar MA. Acetylcholine release from the nerve terminals of the guinea-pig ileum by Naja venoms. Toxicon 1976;14:127-132.
26. Phillips RE, Theakston RD, Warrell DA, Galigedara Y, Abeysekera DT, Dissanayaka P, et al. Paralysis, rhabdomyolysis and haemolysis caused by bites of Russell's viper (Vipera russelli pulchella) in Sri Lanka: failure of Indian (Haffkine) antivenom. Q J Med 1988;68:691-715.
27. Ramasamy S, Isbister GK, Hodgson WC. The efficacy of two antivenoms against the in vitro myotoxic effects of black snake (Pseudechis) venoms in the chick biventer cervicis nerve-muscle preparation. Toxicon 2004;44:837-845.
28. 2 from Vipera ammodytes ammodytes venom. Biochim Biophys Acta 1985;828:306-312.
29. Sket D, Gubensek F. Pharmacological study of phospholipase A from Vipera ammodytes venom. Toxicon 1976;14:393-396.
30. 2 from Bothrops pirajai snake venom. Arch Biochem Biophys 2001;387:188-196.
31. 2 homologue from Bothrops neuwiedi pauloensis venom. Arch Biochem Biophys 2000;378:201-209.
32. 2 homologue from Bothrops jararacussu snake venom. Int J Biochem Cell Biol 2002;34:668-677.
33. Tibballs J, Kuruppu S, Hodgson WC, Carroll T, Hawdon G, Sourial M, et al. Cardiovascular, haematological and neurological effects of the venom of the Papua New Guinean small-eyed snake (Micropechis ikaheka) and their neutralisation with CSL polyvalent and black snake antivenoms. Toxicon 2003; 42:647-655.
34. 2 of snake venom. Biochim Biophys Acta 1987;916:94-99.
35. 2. Biochemistry 1974;13:1446-1454.
36. Warrell DA, Hudson BJ, Lalloo DG, Trevett AJ, Whitehead P, Bamler PR, et al. The emerging syndrome of envenoming by the New Guinea small-eyed snake Micropechis ikaheka. Q J Med 1996;89:523-530.
37. 2 myotoxin from the venom of the Irian Jayan death adder (Acanthophis rugosus). Br J Pharmacol 2003;138: 333-342.
38. Wickramaratna JC, Hodgson WC. A pharmacological examination of venoms from three species of death adder (Acanthophis antarcticus, Acanthophis praelongus and Acanthophis pyrrhus). Toxicon 2001;39:209-216.
39. Worrell E. Reptiles of Australia. Sydney: Angus & Robertson; 1970.
40. Wrogemann K, Pena SD. Mitochondrial calcium overload: a general mechanism for cell-necrosis in muscle diseases. Lancet 1976;1:672-674.