Amino acid substitution in Trichophyton rubrum squalene epoxidase associated with resistance to terbinafine

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 7, 2005, Pages 2840-2844

  Osborne, Colin S ^a,b   Leitner, Ingrid ^a   Favre, Bertrand ^a,c   Ryder, Neil S ^a,b  

^a Novartis Institutes for Biomedical Research   (Austria)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; SQUALENE EPOXIDASE INHIBITOR; SQUALENE MONOOXYGENASE; TERBINAFINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; CANDIDA ALBICANS; DERMATOPHYTE; FUNGUS ISOLATION; GENE SEQUENCE; INTRON; MINIMUM INHIBITORY CONCENTRATION; MISSENSE MUTATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TRICHOPHYTON RUBRUM;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIFUNGAL AGENTS; CLONING, MOLECULAR; DRUG RESISTANCE, FUNGAL; FUNGAL PROTEINS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; NAPHTHALENES; OXYGENASES; SEQUENCE ANALYSIS, DNA; SQUALENE MONOOXYGENASE; TRICHOPHYTON;

EID: 21444431505     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.7.2840-2844.2005     Document Type: Article

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