Flexible Coupling of a Waveguide Detector with a Microscale Field Flow Fractionation Device

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 5345, Issue , 2004, Pages 250-257

  Sant, Himanshu J ^a   Gale, Bruce K ^a  

^a University of Utah   (United States)

Author keywords

Micro total analysis systems; Optical detection; Packaging; Sample preparation; Separation

Indexed keywords

BLOOD; CHANNEL FLOW; CHROMATOGRAPHIC ANALYSIS; COST EFFECTIVENESS; INTERFACES (MATERIALS); RAPID PROTOTYPING; SEPARATION; SIGNAL TO NOISE RATIO; ULTRAVIOLET RADIATION;

MICRO TOTAL ANALYSIS SYSTEMS; OPTICAL DETECTION; POLYMER BASED MICROSYSTEMS; SAMPLE PREPARATION;

OPTICAL WAVEGUIDES;

EID: 2142840928     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.529377     Document Type: Conference Paper

References (21)

1. D. R. Reyes; D. Iossifidis, P-A. Auroux, A. Manz, "Micro total analysis systems. 1. Introduction, theory, and technology," Analytical Chemistry, vol. 74, n. 12, (2623-2636), 2002.
2. P-A. Auroux, D. Iossifidis, D. R. Reyes; A. Manz, "Micro total analysis systems. 2. Analytical standard operations and applications "Analytical Chemistry, vol. 74, n. 12, (2637-2652), 2002.
3. I. L. Medintz, B. M. Paegel, R. A. Mathies, R.A., "Microfabricated capillary array electrophoresis DNA analysis systems" Journal of Chromatography A, vol. 924, n. 1-2, (265-270), 2001.
4. Y. Fintschenko, Wen-Yee. Choi, Eric B Cummings,.; J. Frechet, Julia A. Fruetel, Emily F. Hilder, Emily F.; Dieudonne A Mair, Timothy J. Shepodd, Frantisek Svec, "An answer in the palm of your hand: Microfluidics for analytical applications" Proceedings of SPIE - The International Society for Optical Engineering, vol. 4982, (196-207), The International Society for Optical Engineering, San Jose, 2003.
5. Bruce K. Gale, Karin D. Caldwell, and A. Bruno Frazier, "A Micromachined Electrical Field- Flow Fractionation System," IEEE Tran. on Biomedical Engineering, vol. 45, n. 12, (1459-1469), 1998.
6. T. Thorsen, Sebastian J Maerkl,.; Stephen R. Quake, "Microfluidic large-scale integration", Science, v 298, n 5593, (580-584), 2002.
7. Michael R.McNeely, Mark K. Spute, Nadeem A. Tusneem, Arnold R. Oliphant, "Hydrophobic microfluidics," Proceedings of SPIE - The International Society for Optical Engineering, vol. 3877, (210-220), The International Society for Optical Engineering, Santa Clara, 1999,
8. Mark L. Adams, Markus Enzelberger, Stephen Quake, Axel Scherer, "Microfluidic integration on detector arrays for absorption and fluorescence micro-spectrometers," Sensors and Actuators, A: Physical, vol. 104, n. 1, (25-31), 2003.
9. C. D. Costin, Robert E. HSynovec, H"Measuring the transverse concentration gradient between adjacent laminar flows in a microfluidic device by a laser-based refractive index gradient detector," Talanta, vol. 58, n. 3, (551-560), 2002.
10. Joseph Wang, "Electrochemical detection for microscale analytical systems: A review," Talanta, vol. 56, n. 2, (223-231) 2002.
11. Nghia HChiem, HLoranelle Lockyear-Shultz, Per Andersson, Cameron Skinner, Jed D. Harrison, D., "Room temperature bonding of micromachined glass devices for capillary electrophoresis," Sensors and Actuators, B: Chemical vol. 63, n. 3, (147-152), 2000.
12. Siyi Lai, James L. HLee,H Liyong HYu,H Kurt W HKoelling,.H; HMarMadou, Marc J.H, "Micro- and nano-fabrication of polymer based microfluidic platforms for BioMEMS applications," Proceedings of Materials Research Society Symposium - Proceedings, vol. 729, (17-27), 2002.
13. D.J.Beebe, G. Mensing, J. Moorthy C.M. Khoury and T.M. Pearce "Alternative Approaches To Microfluidic Systems Design, Construction and Operation," Proceedings of Micro TAS 2001, (453-455), Kluwer Academic Publishers, Monterey, 2001.
14. Himanshu J. Sant and Bruce K. Gale, "A Microfabricated Thermal Electric Field Flow Fractionation System," in Proc. of MicroTAS 2001, (563-564), Kluwer Academic Publishers, Monterrey, 2001.
15. Mauro Aiello and Robert McLaren, "A Sensitive Small-Volume UV/Vis Flow Cell and Total Absorbance Detection System for Micro-HPLC," Anal. Chem. vol. 73, (1387-1392), 2001.
16. Tiansong Wang, Joseph H. Aiken, Carmen W. Huie, and Richard A. Hartwick, "Nanoliter-Scale Multireflection Cell for Absorption Detection in Capillary Electrophoresis," Anal. Chem, vol. 63, (1372-1376), 1991.
17. Stephen E. Moring and Richard T. Reel, "Optical Improvements of a Z-Shaped Cell for High-Sensitivity UV Absorbance Detection in Capillary Electrophoresis," Anal. Chem, vol. 65, (3454-3459), 1993.
18. Bruce K. Gale, Ronald S. Besser, Ian Papautsky, John D. Brazzle, A. Bruno Frazier, "Packaging for Biomedical Analysis Systems," Proceedings of the Advanced Technology Workshop (ATW) for MEMS and Microsystem Packaging and Integration, Orlando, 2000
19. A.S. Said, Theory and Mathematics of Chromatography, Dr. Alfred Huethig Publishers, Heidelberg, 1981.
20. T.M. Vickery, Liquid Chromatography Detectors, Marcel Dekker Inc, New York, 1983.
21. Bruce K. Gale, Karin D. Caldwell, and A. Bruno Frazier, "HElectrical Conductivity Particle Detector for Use in Biological and Chemical Micro-analysis SystemsH," Proeedings of SPIE Symposium on Micromachining and Microfabrication: Micro Fluidic Devices and Systems, (230-242), The International Society for Optical Engineering, Santa Clara, 1998.