Simulation and Design of Micro-mixers for Microfluidic Devices

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 5345, Issue , 2004, Pages 183-193

  Maha, Amit ^a   Barrett, Dwhyte O ^a   Nikitopoulos, Dimitris E ^a   Soper, Steve A ^a   Murphy, Michael C ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

MEMS; Microchannel; Microfluidic devices; Microfluidics; Micromixers; Static mixers

Indexed keywords

ASPECT RATIO; CHEMICAL REACTORS; DNA; JETS; LAMINAR FLOW; MICROELECTROMECHANICAL DEVICES; MIXERS (MACHINERY); PRESSURE DROP; PRODUCT DESIGN; SURFACE TREATMENT;

MICROCHANNELS; MICROFLUIDIC DEVICES; MICROFLUIDICS; MICROMIXERS; STATIC MIXERS;

FLUIDIC DEVICES;

EID: 2142839697     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.530788     Document Type: Conference Paper

References (22)

1. Steven A soper, Sean M Ford, Shize Qi, Robin L. McCarley Kevin Kelly, Michael C.Murphy "Polymetric Microelectrmechanical Systems," Analytical Chemistry report, October1, 2000.
2. D. O. Barret, A. Maha, Y. Wang, S. A. Soper, M. C. Murphy, D. E. Nikitopoulos, "Design of Microfabricated Devices for Ligase Detection Reaction (LDR)," Proceedings of SPIE, Vol 5345-10, 2004
3. H.L.Dryden, F.D.Murnaghan, and H. Bateman, "Hydrodynamics", Bull.No.84 pp.197-201.Comm. Hydrodyn., Div.Phys.Sci. Washington DC 1932; reprinted by Dover, New York, 1956.
4. H.L.Dryden, F.D.Murnaghan, and H. Bateman, "Hydrodynamics", Bull.No.84 pp.197-201.Comm. Hydrodyn., Div.Phys.Sci. Washington DC 1932; reprinted by Dover, New York, 1956.
5. D.B.Holmes and J.R. Vermeulen, "Velocity profiles in ducts with rectangular cross sections," Chem. Eng. Sci.23, pp.717-722 (1968).
6. G. F. Muchnik, S.D. Solomonov, and A.R.Gordon, "Hydrodynamic development of a laminar velocity field in rectangular channels," Journal of Eng, Phys. (USSR) 25, pp. 1268-1271 (1973).
7. G. Karniadakis and A. Beskok, "MICRO FLOWS," pp 7-42, Springer, New York, 2002.
8. J. B. Knight, A. Vishwanath, J. P. Brody, and R. H. Austin, "Hydrodynamic focusing on a silicon chip: Mixing nanoliters in microchannels," Physical Review Letters 80(17), pp. 3863-3866, 1998.
9. Z. Yang, S. Matsumoto, H. Goto, M. Matsumoto, and R Maeda, "Ultrasonic micromixer for microfluidic systems," Sensors and Actuators A-Physical 93(3), pp. 266-272, 2001.
10. S. C. Jacobson, T. E. McKnight, and J. M. Ramsey, "Microfluidic devices for electrokinetically driven parallel and serial mixing," Analytical Chemistry 71(20), pp. 4455-4459, 1999.
11. A. E. Kamholz, E. A. Schilling, and P. Yager, "Optical measurement of transverse molecular diffusion in a microchannel," Biophysical Journal 80(4), pp. 1967-1972, 2001.
12. N. Schwesinger, T. Frank, and H. Wurmus, "Modular microfluid system with an integrated micromixer," Journal of Micromechanics and Microengineering 6(1), pp. 99-102, 1996.
13. M. Koch, D. Chatelain, A. Evans, and A. Brunnschweiler, "Two simple micromixers based on silicon," Journal of Micromechanics and Microengineering 8(2), pp. 123-126, 1998.
14. B. He, B. J. Burke, X. Zhang, R. Zhang, and F. E. Regnier, "A picoliter-volume mixer for microfluidic analytical systems," Analytical Chemistry 73(9), pp. 1942-7, 2001.
15. A. D. Stroock, S. K. W. Dertinger, A. Ajdari, I. Mezic, H. A. Stone, and G. M. Whitesides, "Chaotic mixer for microchannels," Science 295(5555), pp. 647-651, 2002.
16. T. J. Johnson, D. Ross, and L. E. Locascio, "Rapid microfluidic mixing," Analytical Chemistry 74(1), pp. 45-51, 2002.
17. R. H. Liu, M. A. Stremler, K. V. Sharp, M. G. Olsen, J. G. Santiago, R. J. Adrian, H. Aref, and D. J. Beebe, "Passive mixing in a three-dimensional serpentine microchannel," Journal of Microelectromechanical Systems 9(2), pp. 190-197, 2000.
18. J. Deval, P. Tabeling, and C. H. Ho, "A Dielectrophoretic Chaotic Mixer," MEMS 2002 IEEE International Conference, ISBN 0-7803-7185-2, pp 36-38.
19. Y. K. Lee, J. Deval, P. Tabeling, and C. H. Ho, "Chaotic mixing in electrokinectically and pressure driven micro flows," MEMS 2001 IEEE International Conference, ISBN 0-7803-5998-4, pp 483-486
20. H. Wang, P. Iovenitti, E. Harvey, and S. Masood, "Optimizing layout of obstacles for enhanced mixing in microchannels," Smart Materials and Structures 11(5), pp. 662-667, 2002.
21. N. L. Jeon, S. K. W. Dertinger, D. T. Chiu, I. S. Choi, A. D. Stroock, and G. M. Whitesides, "Generation of solution and surface gradients using microfluidic systems," Langmuir 16(22), pp. 8311-8316, 2000.
22. D. Erikson and D. Li, "Influence of Surface Hetrogenity on Electrokinectically Driven Microfluidic Mixing," Langmuir 18(5), pp 1883-1892, 2002.