Pattern and predictors of early rejection after lung transplantation

American Journal of Critical Care

Volumn 12, Issue 6, 2003, Pages 497-507

  DeVito Dabbs, Annette ^a   Hoffman, Leslie A ^a   Iacono, Aldo T ^b   Wells, Chris L ^a   Grgurich, Wayne ^b   Zullo, Thomas G ^a   McCurry, Kenneth R ^b   Dauber, James H ^c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; LYMPHOCYTE ANTIBODY; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; THYMOCYTE ANTIBODY; TSUKUBAENOLIDE; IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; BRONCHIOLITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DONOR; FEMALE; GRAFT REJECTION; HUMAN; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; PREDICTION; RECIPIENT; RECURRENT DISEASE; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; TREATMENT FAILURE; CHI SQUARE DISTRIBUTION; CLASSIFICATION; COHORT ANALYSIS; HOSPITALIZATION; MIDDLE AGED; NONPARAMETRIC TEST; PREDICTION AND FORECASTING; PREVALENCE; REGRESSION ANALYSIS; RETROSPECTIVE STUDY; RISK FACTOR; TIME; UNITED STATES;

CHI-SQUARE DISTRIBUTION; COHORT STUDIES; FEMALE; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; PENNSYLVANIA; PREDICTIVE VALUE OF TESTS; PREVALENCE; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 2142802113     PISSN: 10623264     EISSN: None     Source Type: Journal    
DOI: 10.4037/ajcc2003.12.6.497     Document Type: Article

References (54)

1. Arcasoy SM, Kotloff RM. Lung transplantation. N Engl J Med. 1999;340:1081-1091.
2. DeMeo DL, Ginns LC. Lung transplantation at the turn of the century. Annu Rev Med. 2001;52:185-201.
3. Geertsma A, van der Bij W, deBoer WJ, TenVergert EM. Survival with and without lung transplantation. Transplant Proc. 1997;29:630-631.
4. Trulock EP. Lung transplantation. Am J Respir Crit Care Med. 1997; 155:789-818.
5. Trulock EP, Edwards LB, Taylor DO, Boucek MM, Mohacsi PF, Keck BM, Hertz MI. The registry of the International Society for Heart and Lung Transplantation: twentieth official adult lung and heart-lung transplant report. J Heart Lung Transplant. 2003;22:625-635.
6. Bando K, Paradis IL, Komatsu K, et al. Analysis of time-dependent risks for infection, rejection, and death after pulmonary transplantation. J Thorac Cardiovasc Surg. 1995;109:49-57.
7. Chaparro C, Scavuzzo M, Winton T. Status of lung transplant recipients surviving beyond five years. J Heart Lung Transplant. 1997;16:511-516.
8. Yousem SA, Berry GJ, Brunt E, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection. J Heart Lung Transplant. 1990;9:593-601.
9. Cooper JD, Billingham M, Egan T, et al. A working formulation for the standardization of nomenclature and for clinical staging of chronic dysfunction in lung allografts. International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 1993;12:713-716.
10. Cohen L, Littlefield C, Kelly P, Maurer J, Abbey S. Predictors of quality of life and adjustment after lung transplantation. Chest. 1998;113:633-644.
11. Gross CR, Savick K, Bolman RM, Hertz MI. Long-term health status and quality of life outcomes of lung transplant recipients. Chest. 1995; 108:1587-1593.
12. Littlefield C, Abbey S, Fiducia D, et al. Quality of life following transplantation of the heart, liver, and lungs. Gen Hosp Psychiatry. 1996;18 (6 suppl):36S-47S.
13. Ramsey SD, Patrick DL, Albert RK, Larson EB, Wood DE, Raghu G. The cost-effectiveness of lung transplantation. Chest. 1995;108:1594-1601.
14. van den Berg JWK, van Enckevort PJ, TenVergert EM, Postma DS, van der Bij W, Koeter G. Bronchiolitis obliterans syndrome and additional costs of lung transplantation. Chest. 2000;118:1648-1652.
15. Midthun DE, McDougall JC, Peters SG, Scott JP. Medical management and complications in the lung transplant recipient. Mayo Clin Proc. 1997;72:175-184.
16. King-Biggs MB. Acute pulmonary allograft rejection: mechanisms, diagnosis, and management. Clin Chest Med. 1997;18:301-310.
17. McGregor CGA, Baldwin JC, Jamieson SW, et al. Isolated pulmonary rejection after combined heart-lung transplantation. J Thorac Cardiovasc Surg. 1985;90:623-626.
18. Boehler A, Estenne M. Obliterative bronchiolitis after lung transplantation. Curr Opin Pulm Med. 2000;6:133-139.
19. Garrity ER Jr. Bronchiolitis obliterans syndrome in lung transplantation: risk factors and markers for development of the disease. Curr Opin Organ Transplant. 2000;5:390-395.
20. Heng D, Sharples LD, McNeil K, Stewart S, Wreghitt T, Wallwork J. Bronchiolitis obliterans syndrome: incidence, natural history, prognosis, and risk factors. J Heart Lung Transplant. 1998;17:1255-1263.
21. Husain AN, Gaweco AS. Lung transplantation. Curr Opin Organ Transplant. 2000;5:383.
22. Scott JP, Higenbottam TW, Sharples L, et al. Risk factors for obliterative bronchiolitis in heart-lung transplant recipients. Transplantation. 1991; 51:813-817.
23. Rao PN, Zeevi A, Snyder J, et al. Monitoring acute lung rejection and infection by bronchoalveolar lavage and plasma levels of hyaluronic acid in clinical lung transplantation. J Heart Lung Transplant. 1994;13:958-962.
24. Finkelstein SM, Snyder M, Edin-Stubbe C, et al. Monitoring progress after lung transplantation from home: patient adherence. J Med Eng Technol. 1996;20:203-210.
25. Zeevi A, Uknis ME, Spichty KJ, et al. Proliferation of cytomegalovirus-primed lymphocytes in bronchoalveolar lavage from lung transplant patients. Transplantation. 1992;54:635-639.
26. Treede H, Klepetko W, Reichenspurner H, et al. Tacrolimus versus cyclosporine after lung transplantation: a prospective, open, randomized two-center trial comparing two different immunosuppressive protocols. J Heart Lung Transplant. 2001;20:511-517.
27. Griffith BP, Bando K, Hardesty RL, et al. A prospective randomized trial of FK506 versus cyclosporine after human pulmonary transplantation. Transplantation. 1994;57:848-851.
28. Keenan RJ, Konishi H, Kawai A, et al. Clinical trial of tacrolimus versus cyclosporine in lung transplantation. Ann Thorac Surg. 1995;60:580-585.
29. Yousem SA, Berry GJ, Cagle PT, et al. Revision of the 1990 working formulation for the classification of pulmonary allograft rejection. Lung Rejection Study Group. J Heart Lung Transplant. 1996;15(1 pt 1):1-15.
30. Yousem SA, Dauber JH, Keenan R, Paradis IL, Zeevi A, Griffith BP. Does histologic acute rejection in lung allografts predict the development of bronchiolitis obliterans? Transplantation. 1991;52:306-309.
31. Yousem SA. Lymphocytic bronchitis/bronchiolitis in lung allograft recipients. Am J Surg Pathol. 1993;17:491-496.
32. Sharples L, Stewart, S. Immunologic mechanisms underlying bronchiolitis obliterans. Curr Opin Organ Transplant. 2000;5:384-389.
33. Maurer JR, Morrison D, Winton T, Patterson GA. Late pulmonary complications of isolated lung transplantation. Transplant Proc. 1991;23:1224-1225.
34. Stanbrook MW, Kesten S. Bronchial hyperreactivity after lung transplantation predicts early bronchiolitis obliterans. Am J Respir Crit Care Med. 1999;160:2034-2039.
35. Reynaud-Gaubert M, Thomas P, Badier M, Cau P, Giudicelli R, Fuentes P. Early detection of airway involvement in obliterative bronchiolitis after lung transplantation. Am J Respir Crit Care Med. 2000;161:1924-1929.
36. Martinez JA, Paradis IL, Dauber JH, et al. Spirometry values in stable lung transplant recipients. Am J Respir Crit Care Med. 1997;155:285-290.
37. Guilinger RA, Paradis IL, Dauber JH, et al. The importance of bronchoscopy with transbronchial biopsy and bronchoalveolar lavage in the management of lung transplant recipients. Am J Respir Crit Care Med. 1995;152:2037-2043.
38. Chamberlain D, Maurer J, Chaparro C, Idolor L. Evaluation of transbronchial lung biopsy specimens in the diagnosis of bronchiolitis obliterans after lung transplantation. J Heart Lung Transplant. 1994;13:963-971.
39. Chan CC, Abi-Saleh WJ, Arroliga AC, et al. Diagnostic yield and therapeutic impact of flexible bronchoscopy in lung transplant recipients. J Heart Lung Transplant. 1996;15:196-205.
40. Kramer M, Marshall S, Starnes V, Gamberg P, Amitai Z, Theodore J. Infectious complications in heart-lung transplantation: analysis in 200 episodes. Arch Intern Med. 1993;153:2010-2016.
41. Pomerance A, Madden B, Burke MM, Yacoub MH. Transbronchial biopsy in heart and lung transplantation: clinicopathologic correlations. J Heart Lung Transplant. 1995;14:761-773.
42. Yousem SA, Paradis I, Griffith BP. Can transbronchial biopsy aid in the diagnosis of bronchiolitis obliterans in lung transplant recipients? Transplantation. 1994;57:151-153.
43. Keenan RJ, Iacono A, Dauber JH, et al. Treatment of refractory acute rejection with aerosolized cyclosporine. J Thorac Cardiovasc Surg. 1997; 113:335-341.
44. Iacono AT, Smaldone GC, Keenan RJ, et al. Dose-related reversal of acute lung rejection by aerosolized cyclosporine. Am J Respir Crit Care Med. 1997;155:1690-1698.
45. Iacono A, Keenan, RJ, Duncan, SR, et al. Aerosolized cyclosporine in lung recipients with refractory chronic rejection. Am J Respir Crit Care Med. 1996;153(4 pt 1):1451-1455.
46. Bando K, Paradis IL, Similo S, et al. Obliterative bronchiolitis after lung and heart-lung transplantation: an analysis of risk factors and management. J Cardiovasc Surg. 1995;110:4-14.
47. Fox JMK, Jessurum J, Kshettry V, Savick K, Hertz ML. Clinically acute silent rejection following lung transplantation: the role of surveillance bronchoscopy [abstract]. Am J Respir Crit Care Med. 1994;149:1094A.
48. Sibley RK, Berry GJ, Tazelaar HD, et al. The role of transbronchial biopsies in the management of transplant recipients. J Heart Lung Transplant. 1993;12:308-324.
49. DeVito Dabbs A, Hoffman LA, Iacono A, Zullo T, McCurry K, Dauber JH. Examining the usefulness of symptomatology to differentiate between acute rejection and pulmonary infection after lung transplantation [abstract]. Am J Respir Crit Care Med. 2003;167(7):A243.
50. Bjortuft O, Johansen B, Boe J, et al. Daily home spirometry facilitates detection of rejection in single lung transplant recipients with emphysema. Eur Respir J. 1993;6:705-708.
51. Finkelstein SM, Hertz MH, Snyder M, et al. Early detection of infection and rejection in lung transplantation. Proc Soc Exp Biol Med. 1994;16:S62-S63.
52. Finkelstein SM, Lindgren B, Prasad B, et al. Reliability and validity of spirometry measurements in a paperless home monitoring diary program for lung transplantation. Heart Lung. 1993;22:523-533.
53. Lindgren B, Finkelstein SM, Prasad B, et al. Determination of reliability and validity in home monitoring data of pulmonary function tests following lung transplantation. Res Nurs Health. 1997;20:539-550.
54. Fracchia C, Callegari G, Volpato G. Monitoring of lung rejection with home spirometry. Transplant Proc. 1995;27:2000-2001.