Design, synthesis and anticonvulsive activity of analogs of γ-vinyl GABA

Farmaco

Volumn 59, Issue 5, 2004, Pages 381-388

  Zhao, Long Xuan ^b   Park, Jae Gyu ^a   Moon, Yoon Soo ^a   Basnet, Arjun ^a   Choi, Jongwon ^c   Kim, Eun Kyung ^a   Jeong, Tae Cheon ^a   Jahng, Yurngdong ^a   Lee, Eung Seok ^a  

^a Yeungnam University   (South Korea)

^b LIAONING NORMAL UNIVERSITY   (China)

^c Kyungsung University   (South Korea)

Author keywords

vinyl GABA; Anticonvulsive activity; GABA; Synthesis; Vigabatrin

Indexed keywords

4 (2 PROPYLPENTANOYLAMINO)HEX 5 ENOIC ACID METHYL ESTER; 4 (4 AMINOBUTYRYLAMINO)HEX 5 ENOIC ACID METHYL ESTER; 4 (4 AMINOHEX 5 ENOYLAMINO)HEX 5 ENOIC ACID; 4 (4 AMINOHEX 5 ENOYLAMINO)HEX 5 ENOIC ACID METHYL ESTER; 4 (5 AMINOHEPT 6 ENOYLAMINO)BUTYRIC ACID; 4 (5 AMINOHEPT 6 ENOYLAMINO)BUTYRIC ACID METHYL ESTER; 4 [(PIPERIDINE 3 CARBONYL)AMINO]HEX 5 ENOIC ACID; 4 [(PIPERIDINE 4 CARBONYL)AMINO]HEX 5 ENOIC ACID; 4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; BICUCULLINE; ISONIPECOTIC ACID; NIPECOTIC ACID; PENTETRAZOLE; PICROTOXIN; UNCLASSIFIED DRUG; VALPROIC ACID; VIGABATRIN; VIGABATRIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; SEIZURE; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; DRUG DESIGN; ISONIPECOTIC ACIDS; MALE; MICE; NIPECOTIC ACIDS; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; VALPROIC ACID; VIGABATRIN;

EID: 2142790539     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2004.01.011     Document Type: Article

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