Design and synthesis of anticonvulsive agents as γ-vinyl GABA-based potential dual acting prodrugs and their biological activities

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 7, 2000, Pages 609-613

  Kim, Yong Chul ^a   Zhao, Long Xuan ^a   Kim, Tae Hyung ^a   Je, Sun Mi ^a   Kim, Eun Kyung ^a   Choi, Heesung ^b   Chae, Whi Gun ^c   Park, Minsoo ^d   Choi, Jongwon ^d   Jahng, Yurngdong ^a   Lee, Eung Seok ^a  

^a Yeungnam University   (South Korea)

^b Dong Kook Pharmaceutical Co Ltd   (South Korea)

^c Catholic University of Daegu   (South Korea)

^d Kyungsung University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRROLIDINONE; 2 PYRROLIDONE DERIVATIVE; ISONIPECOTIC ACID; NIPECOTIC ACID; NIPECOTIC ACID DERIVATIVE; PRODRUG; VIGABATRIN;

ANTICONVULSANT ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS;

ANIMALS; ANTICONVULSANTS; BICUCULLINE; DRUG DESIGN; MICE; PENTYLENETETRAZOLE; PICROTOXIN; PRODRUGS; SEIZURES; VIGABATRIN;

EID: 17444436771     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00064-0     Document Type: Article

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