Intratumoral induction of thymidylate synthase mRNA by 5-FU in colorectal cancer patients: Association with survival

Oncology Reports

Volumn 10, Issue 5, 2003, Pages 1425-1429

  Tanaka Nozaki, Motoko ^a   Tajiri, Takashi ^a   Tanaka, Noritake ^a   Furukawa, Kiyonori ^a   Takasaki, Hideaki ^a   Yoshimura, Kazuyasu ^a   Suzuki, Hideyuki ^a   Naito, Zenya ^a   Sugizaki, Yuuichi ^a   Merk, Hans F ^b   Blömeke, Brunhilde ^b   Kato, Shunji ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

5 fluorouracil; Colorectal cancer; Drug efficacy; Survival rate; Thymidylate synthase induction

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; COMPLEMENTARY DNA; FLUOROURACIL; MESSENGER RNA; THYMIDYLATE SYNTHASE;

AGED; ARTICLE; BIOSYNTHESIS; COLORECTAL TUMOR; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; MORTALITY; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; COLORECTAL NEOPLASMS; DNA, COMPLEMENTARY; FEMALE; FLUOROURACIL; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYMIDYLATE SYNTHASE; TIME FACTORS;

EID: 2142745873     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.10.5.1425     Document Type: Article

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