Dihydropyrimidine dehydrogenase, multidrug resistance-associated protein, and thymidylate synthase gene expression levels can predict 5-fluorouracil resistance in human gastrointestinal cancer cells

International Journal of Oncology

Volumn 14, Issue 3, 1999, Pages 551-556

  Kirihara, Yoshimasa ^a   Yamamoto, Wataru ^a   Toge, Tetsuya ^a   Nishiyama, Masahiko ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

5 fluorouracil; Dihydropyrimidine dehydrogenase; Drug resistance; Multidrug resistance associated protein; Thymidylate synthase

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC ANTIMETABOLITE; BIOLOGICAL MARKER; DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; OXIDOREDUCTASE; THYMIDYLATE SYNTHASE;

ARTICLE; CELL CULTURE; DRUG RESISTANCE; DRUG SCREENING; ENZYMOLOGY; GASTROINTESTINAL TUMOR; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MULTIDRUG RESISTANCE;

ANTIMETABOLITES, ANTINEOPLASTIC; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL MARKERS; DIHYDROURACIL DEHYDROGENASE (NADP); DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLUOROURACIL; GASTROINTESTINAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OXIDOREDUCTASES; RNA, MESSENGER; THYMIDYLATE SYNTHASE; TUMOR CELLS, CULTURED;

EID: 0033090335     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.14.3.551     Document Type: Article

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