Proteome changes induced by expression of tumor suppressor PTEN

Molecules and Cells

Volumn 15, Issue 3, 2003, Pages 396-405

  Kim, So Yeon ^a   Kim, Yu Sam ^a   Bahk, Young Yil ^a  

^a Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACT; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; PROTEOME;

ANIMAL CELL; ARTICLE; EMBRYO CELL; FIBROBLAST; GENETIC CODE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; TWO DIMENSIONAL ELECTROPHORESIS; UNINDEXED SEQUENCE; ANIMAL; CELL STRAIN 3T3; GENE EXPRESSION; METABOLISM; TIME; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION;

ANIMALIA;

ANIMALS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; MICE; NIH 3T3 CELLS; PROTEOME; TIME FACTORS; UP-REGULATION;

EID: 2142691768     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Cantley, L. C. and Neel, B. G. (1999) PTEN suppresses tumor formation by retraining the phosphoinositide 3-kinase/AKT pathway. Proc. Natl. Acad. Sci. USA 96, 4240-4245.
2. Fakih, M., Johnson, C. S., and Trump, D. L. (2002) Glucocorticoids and treatment of prostate cancer: a preclinical and clinical review. Urology 60, 553-611.
3. Gossen, M., Freundieb, S., Bender, G., Muller, G., Hillen, W., and Bujard, H. (1995) Transcriptional activation by tetracyclines in mammalian cells. Science 268, 1766-1769.
4. Gygi, S. P., Rochon, Y., Franza, B. R., and Aebersold, R. (1999) Correlation between protein and mRNA abundance in yeast. Mol. Cell. Biol. 19, 1720-1730.
5. Jambunathan, N., Siani, J. M., and McNellis, T. W. (2001) A humidity-sensitive arabidopsis copine mutant exhibits precocious cell death and increased disease resistance. Plant Cell. 13, 2225-2240.
6. Kinoshita, J. H. and Nishimura, C. (1988) The involvement of aldose reductase in diabetic complications. Diabetes Metab. Rev. 4, 323-357.
7. Kireeva, M. L., Mo, F. E., Yang, G. P., and Lau, L. F. (1996) Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration and adhesion. Mol. Cell. Biol. 16, 1326-1334.
8. Kurose, K., Zhou, X. P., Araki, T., Cannistra, S. A., Maher, E. R., and Eng, C. (2001) Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas. Am. J. Pathol. 158, 2097-2106.
9. Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275, 1943-1947.
10. Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., and Parsons, R. (1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Res. 58, 5667-5672.
11. Macias, M. J., Wiesner, S., and Sudol, M. (2002) WW and SH3 domains, two different scaffolds to recognize proline-rich ligands. FEBS Lett. 513, 30-37.
12. Maehama, T. and Dixon, J. E. (1998) The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273, 13375-13378.
13. Maehama, T. and Dixon, J. E. (1999) PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol. 9, 125-128.
14. Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., and Tonks, N. K. (1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc. Natl. Acad. Sci. USA 94, 9052-9057.
15. O'Brian, T. P., Yang, G. P., Sanders, L., and Lau, L. F. (1990) Expression of CYR61, a growth factor-inducible immediate-early gene. Mol. Cell. Biol. 10, 3569-3577.
16. Shevchenko, A., Wilm, M., Vorm, O., and Mann, M. (1996) Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels. Anal. Chem. 68, 850-858.
17. Smith, R. G., Syms, A. J., and Norris, J. S. (1984) Differential effects of androgens and glucocorticoids on regulation of androgen receptor concentrations and cell growth. J. Steroid Biochem. 20, 277-281.
18. Stambolic, V., Suzuki, A., de la Pompa, J. L., Brothers, G. M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J. M., Siderovski, D. P., and Mak, T. W. (1998) Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95, 29-39.
19. Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R., and Yamada, K. M. (1998) Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280, 1614-1617.
20. 2+ -dependent phospholipid-binding proteins. Cell Mol. Life Sci. 59, 1467-1477.
21. Vazquez, F. and Sellers, W. R. (2000) The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling. Biochem. Biophys. Acta 1470, M21-35.
22. Yan, J. X., Wait, R., Berkelman, T., Harry, R. A., Westbrook, J. A., Wheeler, C. H., and Dunn, M. J. (2000) A modified silver staining protocol for visualization of proteins compatible with matrix assisted laser desorption/ionization and electrospray ionization-mass spectrometry. Electrophoresis 21, 3666-3672.
23. Zhu, H., Iaria, J., and Sizeland, A. M. (1999) Smad7 differentially regulates transforming growth factor β-mediated signaling pathways. J. Biol. Chem. 274, 32258-32264.