Co-existence of hyperparathyroidism, hypergastrinaemia and multiple gastric carcinoids is not always due to incomplete expression of the MEN-1 syndrome

Digestive and Liver Disease

Volumn 35, Issue 8, 2003, Pages 585-589

  Corleto, V D ^a   Goebel, S U ^b   Panzuto, F ^a   Jensen, R T ^b   Delle Fave, G ^a   Annibale, B ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Gastric carcinoid; Hypergastrinaemia; Hyperparathyroidism; Multiple endocrine neoplasia type 1

Indexed keywords

GASTRIN; OMEPRAZOLE; PARATHYROID HORMONE;

ABDOMINAL ANGIOGRAPHY; AGED; APUDOMA; ARTICLE; ATROPHIC GASTRITIS; CARCINOID; CASE REPORT; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; EPIGASTRIC PAIN; EXON; FEMALE; GASTRIN BLOOD LEVEL; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; HYPERGASTRINEMIA; HYPERPARATHYROIDISM; IMMUNORADIOMETRIC ASSAY; MULTIPLE ENDOCRINE NEOPLASIA; MUTATIONAL ANALYSIS; PARATHYROID HORMONE BLOOD LEVEL; PARATHYROIDECTOMY; PATHOGENESIS; POLYMERASE CHAIN REACTION; RADIOIMMUNOASSAY; STOMACH BIOPSY; STOMACH CARCINOID; ZOLLINGER ELLISON SYNDROME; BLOOD; GENE EXPRESSION; GENETICS; STOMACH TUMOR;

AGED; CARCINOID TUMOR; DIAGNOSIS, DIFFERENTIAL; FEMALE; GASTRINS; GASTRITIS, ATROPHIC; GENE EXPRESSION; HUMANS; HYPERPARATHYROIDISM; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; STOMACH NEOPLASMS;

EID: 2142645982     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1590-8658(03)00278-0     Document Type: Article

References (25)

1. Godwin JD. Carcinoid tumours. An analysis of 2837 cases. Cancer 1975;36:560-9.
2. Modlin IM, Sandor A. An analysis of 8305 cases of carcinoid tumours. Cancer 1997;79:813-29.
3. Kulke MH, Mayer RJ. Carcinoid tumours. New Engl J Med 1999;340:858-68.
4. Rindi G, Luinetti O, Cornaggia M, Capella C, Solcia E. Three types of gastric argyrophil carcinoid and the gastric neuroendocrine carcinoma: A clinicopathologic study. Gastroenterology 1993;104:994-1006.
5. Stewler GJ, Rosenblatt M. Mineral metabolism. In: Felig P, Baxter JD, Frohman LA, editors, Endocrinology and metabolism, 3rd ed, New York: McGraw-Hill; 1995, pp. 1407-516.
6. Corleto VD, Minisola S, Moretti A, Damiani C, Grossi C, Ciardi S, et al. Prevalence and causes of hypergastrinaemia in primary hyperparathyroidism: a prospective study. J Clin Endocrinol Metab 1999;84:4554-8.
7. Rode J, Dhillon AP, Cotton PB, Woolf A, O'Riordan JLH. Carcinoid tumour of stomach and primary hyperparathyroidism: a new association. J Clin Pathol 1987;40:546-51.
8. Alberti-Flor JJ, Halter S, Dunn GD. Multiple gastric carcinoids in a patient with a history of primary hyperparathyroidism. Am J Gastroenterol 1985;80:531-4.
9. Nores JM, Dalayeun JF, Remy JM, Nenna AD. Gastric carcinoid tumour and parathyroid adenoma. Gut 1988;29:689-90.
10. Annibale B, De Magistris L, Corleto V, D'Ambra G, Marignani M, Iannoni C, et al. Zollinger-Ellison syndrome and antral G-cell hyperfunction in patients with resistant duodenal ulcer disease. Aliment Pharmacol Ther 1994;8:87-93.
11. Delle Fave G, Kohn A, De Magistris L, Annibale B, Bruzzone R, Sparvoli C, et al. Effect of bombesin on gastrin and gastric acid secretion in patients with duodenal ulcer. Gut 1983;24:231-5.
12. Bordi C, Annibale B, Azzoni C, Marignani M, Ferraro G, Antonelli G, et al. Endocrine cell growths in atrophic body gastritis. Critical evaluation of a histological classification. J Pathol 1997;182:339-46.
13. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston, TX, 1994. Am J Surg Pathol 1996;20:1161-81.
14. Solcia E, Bordi C, Creutzfeldt W, Dayal Y, Dayan AD, Falkmer S, et al. Histopathological classification of nonantral gastric endocrine growths in man. Digestion 1988;41:185-200.
15. Zhuang Z, Vortmeyer AO, Pack S, Huang S, Pham TA, Wang C, et al. Somatic mutations of the MEN-1 tumour suppressor gene in sporadic gastrinomas and insulinomas. Cancer Res 1997;57:4682-6.
16. D'Adda T, Keller G, Bordi C, Hofler H. Loss of heterozygosity in 11q13-14 regions in gastric neuroendocrine tumours not associated with multiple endocrine neoplasia type 1 syndrome. Lab Invest 1999;79:671-7.
17. Beckmann MW, Picard F, An HX, van Roeyen CRC, Dominik SI, Mosny DS, et al. Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer. Br J Cancer 1996;73:1220-6.
18. Agarwal SK, Kester MB, Debelenko LV, Heppner C, Emmert-Buck MR, Skarulis MC, et al. Germline mutations of the MEN-1 gene in familial multiple endocrine neoplasia type 1 and related states. Hum Mol Genet 1997;6:1169-75.
19. Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Skarulis MC, et al. Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias. Recent Prog Horm Res 1999;54:397-438.
20. Chandrasekharappa SC, Guru SC, Manickam P, Olufemi SE, Collins FS, Emmert-Buck MR, et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science 1997;276:404-7.
21. Corleto VD, Delle Fave G, Jensen RT. Molecular insights into gastrointestinal neuroendocrine tumours: importance and recent advances. Dig Liver Dis 2002;34:668-80.
22. Hessman O, Lindberg D, Skogseid B, Carling T, Hellman P, Rastad J, et al. Mutation of the multiple endocrine neoplasia type 1 gene in nonfamilial, malignant tumours of the endocrine pancreas. Cancer Res 1998;58:377-9.
23. Delle Fave G, Marignani M, Corleto VD, Angeletti S, D'Ambra G, Ferraro G, et al. Progression of gastric enterochromaffin-like cells growth in Zollinger-Ellison syndrome and atrophic body gastritis patients. Dig Liver Dis 2002;34:270-8.
24. Azzoni C, Doglioni C, Viale G, Delle Fave G, De Boni M, Caruana P, et al. Involvement of bcl-2 oncoprotein in the development of enterochromaffin-like cell gastric carcinoids. Am J Surg Pathol 1996;20:433-41.
25. Marignani M, Delle Fave G, Mecarocci S, Bordi C, Angeletti S, D'Ambra G, et al. High prevalence of atrophic body gastritis in patients with unexplained microcytic and macrocytic anaemia: a prospective screening study. Am J Gastroenterol 1999;94:766-72.