메뉴 건너뛰기




Volumn 54, Issue 7, 2005, Pages 2212-2218

Erythromycin antagonizes the deceleration of gastric emptying by glucagon-like peptide 1 and unmasks its insulinotropic effect in heathy subjects

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; CISAPRIDE; DOMPERIDONE; ERYTHROMYCIN; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; GLUCOSE OXIDASE; INSULIN; METOCLOPRAMIDE; MOTILIUM SAFT; PANCREAS POLYPEPTIDE; PHENOLSULFONPHTHALEIN; PLACEBO; PROPULSIN SAFT;

EID: 21344454659     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.54.7.2212     Document Type: Article
Times cited : (107)

References (45)
  • 1
    • 33845344395 scopus 로고
    • Plasma insulin response to oral and intravenous glucose administration
    • Elrick H, Stimmler L, Hlad CJ, Arai Y: Plasma insulin response to oral and intravenous glucose administration. J Clin Endocrinol Metab 24:1076-1082, 1964
    • (1964) J Clin Endocrinol Metab , vol.24 , pp. 1076-1082
    • Elrick, H.1    Stimmler, L.2    Hlad, C.J.3    Arai, Y.4
  • 2
    • 0018758893 scopus 로고
    • The incretin concept today
    • Creutzfeldt W: The incretin concept today. Diabetologia 16:75-85, 1979
    • (1979) Diabetologia , vol.16 , pp. 75-85
    • Creutzfeldt, W.1
  • 3
  • 4
    • 0015015451 scopus 로고
    • A astric inhibitory polypeptide. I: The amino acid composition and the tryptic peptides
    • Brown JC: A astric inhibitory polypeptide. I: the amino acid composition and the tryptic peptides. Can J Biochem 49:255-261, 1971
    • (1971) Can J Biochem , vol.49 , pp. 255-261
    • Brown, J.C.1
  • 5
    • 0017189728 scopus 로고
    • The insulinotropic action of gastric inhibitory polypeptide in the perfused rat pancreas
    • Pederson RA, Brown JC: The insulinotropic action of gastric inhibitory polypeptide in the perfused rat pancreas. Endocrinology 99:780-785, 1976
    • (1976) Endocrinology , vol.99 , pp. 780-785
    • Pederson, R.A.1    Brown, J.C.2
  • 6
    • 0023638829 scopus 로고
    • Glucagon-like peptide-1 [7-36]: A physiological incretin in man
    • Kreymann B, Williams G, Ghatei MA, Bloom SR: Glucagon-like peptide-1 [7-36]: a physiological incretin in man. Lancet 2:1300-1304, 1987
    • (1987) Lancet , vol.2 , pp. 1300-1304
    • Kreymann, B.1    Williams, G.2    Ghatei, M.A.3    Bloom, S.R.4
  • 7
    • 0028883257 scopus 로고
    • Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide
    • Kolligs F, Fehmann HC, Göke R, Göke B: Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide. Diabetes 44:16-19, 1995
    • (1995) Diabetes , vol.44 , pp. 16-19
    • Kolligs, F.1    Fehmann, H.C.2    Göke, R.3    Göke, B.4
  • 8
    • 0032960834 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: Studies with the antagonist exendin 9-39
    • Edwards CM, Todd JF, Mahmoudi M, Wang Z, Wang RM, Ghatei MA, Bloom SR: Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 9-39. Diabetes 48:86-93, 1999
    • (1999) Diabetes , vol.48 , pp. 86-93
    • Edwards, C.M.1    Todd, J.F.2    Mahmoudi, M.3    Wang, Z.4    Wang, R.M.5    Ghatei, M.A.6    Bloom, S.R.7
  • 10
    • 0037667613 scopus 로고    scopus 로고
    • Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes
    • Meier JJ, Gallwitz B, Salmen S, Goetze O, Holst JJ, Schmidt WE, Nauck MA: Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes. J Clin Endocrinol Metab 88:2719-2725, 2003
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2719-2725
    • Meier, J.J.1    Gallwitz, B.2    Salmen, S.3    Goetze, O.4    Holst, J.J.5    Schmidt, W.E.6    Nauck, M.A.7
  • 11
    • 0027281591 scopus 로고
    • Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects
    • Horowitz M, Edelbroek MA, Wishart JM, Straathof JW: Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects. Diabetologia 36:857-862, 1993
    • (1993) Diabetologia , vol.36 , pp. 857-862
    • Horowitz, M.1    Edelbroek, M.A.2    Wishart, J.M.3    Straathof, J.W.4
  • 13
    • 0014272104 scopus 로고
    • New clinical method for measuring the rate of gastric emptying; the double sampling test meal
    • George JD: New clinical method for measuring the rate of gastric emptying; the double sampling test meal. Gut 9:237-242, 1968
    • (1968) Gut , vol.9 , pp. 237-242
    • George, J.D.1
  • 14
    • 0019395550 scopus 로고
    • Measuring gastric volume by dilution
    • Hurwitz A: Measuring gastric volume by dilution. Gut 22:85-93, 1981
    • (1981) Gut , vol.22 , pp. 85-93
    • Hurwitz, A.1
  • 15
    • 0023104848 scopus 로고
    • Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2)
    • Ørskov C, Holst JJ: Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2). Scand J Clin Lab Invest 47:165-174, 1987
    • (1987) Scand J Clin Lab Invest , vol.47 , pp. 165-174
    • Ørskov, C.1    Holst, J.J.2
  • 16
    • 0020456354 scopus 로고
    • Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin
    • Holst JJ: Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin. Biochem J 207:381-388, 1982
    • (1982) Biochem J , vol.207 , pp. 381-388
    • Holst, J.J.1
  • 17
    • 0033766716 scopus 로고    scopus 로고
    • Degradation of endogenous and exogenous gastric inhibitory polypeptide (GIP) in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide
    • Deacon CF, Nauck MA, Meier JJ, Hücking K, Holst JJ: Degradation of endogenous and exogenous gastric inhibitory polypeptide (GIP) in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide. J Clin Endocrinol Metab 85:3575-3581, 2000
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3575-3581
    • Deacon, C.F.1    Nauck, M.A.2    Meier, J.J.3    Hücking, K.4    Holst, J.J.5
  • 18
    • 0030962231 scopus 로고    scopus 로고
    • The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation
    • Wettergren A, Wojdemann M, Meisner S, Stadil F, Holst JJ: The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation. Gut 40:597-601, 1997
    • (1997) Gut , vol.40 , pp. 597-601
    • Wettergren, A.1    Wojdemann, M.2    Meisner, S.3    Stadil, F.4    Holst, J.J.5
  • 20
    • 0033304603 scopus 로고    scopus 로고
    • The glucagon-like peptides
    • Kieffer TJ, Habener JF: The glucagon-like peptides. Endocr Rev 20:876-913, 1999
    • (1999) Endocr Rev , vol.20 , pp. 876-913
    • Kieffer, T.J.1    Habener, J.F.2
  • 22
    • 0015791989 scopus 로고
    • Stimulation of insulin secretion by gastric inhibitory polypeptide in man
    • Dupré J, Ross SA, Watson D, Brown JC: Stimulation of insulin secretion by gastric inhibitory polypeptide in man. J Clin Endocrinol Metab 37:826-828, 1973
    • (1973) J Clin Endocrinol Metab , vol.37 , pp. 826-828
    • Dupré, J.1    Ross, S.A.2    Watson, D.3    Brown, J.C.4
  • 23
    • 0027419106 scopus 로고
    • Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations
    • Nauck MA, Bartels E, Ørskov C, Ebert R, Creutzfeldt W: Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations. J Clin Endocrinol Metab 76:912-917, 1993
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 912-917
    • Nauck, M.A.1    Bartels, E.2    Ørskov, C.3    Ebert, R.4    Creutzfeldt, W.5
  • 24
    • 0038121744 scopus 로고    scopus 로고
    • Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
    • Vilsbøll T, Krarup T, Madsbad S, Holst JJ: Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. Regul Pept 114:115-121, 2003
    • (2003) Regul Pept , vol.114 , pp. 115-121
    • Vilsbøll, T.1    Krarup, T.2    Madsbad, S.3    Holst, J.J.4
  • 25
    • 0017757854 scopus 로고
    • The effect of gastrin, gastric inhibitory polypeptide, secretion, and the octapeptide of cholecystokinin upon immunoreactive somatostatin release by the perfused canine pancreas
    • Ipp E, Dobbs R, Harris V, Arimura A, Vale W, Unger RU: The effect of gastrin, gastric inhibitory polypeptide, secretion, and the octapeptide of cholecystokinin upon immunoreactive somatostatin release by the perfused canine pancreas. J Clin Invest 60:1216-1219, 1977
    • (1977) J Clin Invest , vol.60 , pp. 1216-1219
    • Ipp, E.1    Dobbs, R.2    Harris, V.3    Arimura, A.4    Vale, W.5    Unger, R.U.6
  • 26
    • 0024263779 scopus 로고
    • Stimulatory effects of cholecystokinin on isolated perifused islets inhibited by potent and specific antagonist L 364718
    • Zawalich WS, Diaz VA, Zawalich KC: Stimulatory effects of cholecystokinin on isolated perifused islets inhibited by potent and specific antagonist L 364718 [corrected]. Diabetes 37:1432-1437, 1988
    • (1988) Diabetes , vol.37 , pp. 1432-1437
    • Zawalich, W.S.1    Diaz, V.A.2    Zawalich, K.C.3
  • 27
    • 23444448321 scopus 로고
    • Treatment with an oral proteinase inhibitor slows gastric emptying and acutely reduces glucose and insulin levels after a liquid meal in type II diabetic patients
    • Schwartz JG, Guan D, Green GM, Phillips WT: Treatment with an oral proteinase inhibitor slows gastric emptying and acutely reduces glucose and insulin levels after a liquid meal in type II diabetic patients. Diabetes Care 17:255-262, 1994
    • (1994) Diabetes Care , vol.17 , pp. 255-262
    • Schwartz, J.G.1    Guan, D.2    Green, G.M.3    Phillips, W.T.4
  • 29
    • 0015606796 scopus 로고
    • Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum
    • Polak JM, Bloom SR, Kuzio M, Brown JC, Pearse AGE: Cellular localization of gastric inhibitory polypeptide in the duodenum and jejunum. Gut 14:284-288, 1973
    • (1973) Gut , vol.14 , pp. 284-288
    • Polak, J.M.1    Bloom, S.R.2    Kuzio, M.3    Brown, J.C.4    Age, P.5
  • 30
    • 0037784011 scopus 로고    scopus 로고
    • GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine
    • Mortensen K, Petersen LL, Holst JJ, Ørskov C: GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine. Regul Pept 114:189-196, 2003
    • (2003) Regul Pept , vol.114 , pp. 189-196
    • Mortensen, K.1    Petersen, L.L.2    Holst, J.J.3    Ørskov, C.4
  • 33
    • 0033306457 scopus 로고    scopus 로고
    • Cisapride versus placebo for 8 weeks on glycemic control and gastric emptying in insulin-dependent diabetes: A double blind cross-over trial
    • Stacher G, Schernthaner G, Francesconi M, Kopp HP, Bergmann H, Stacher-Janotta G, Weber U: Cisapride versus placebo for 8 weeks on glycemic control and gastric emptying in insulin-dependent diabetes: a double blind cross-over trial. J Clin Endocrinol Metab 84:2357-2362, 1999
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2357-2362
    • Stacher, G.1    Schernthaner, G.2    Francesconi, M.3    Kopp, H.P.4    Bergmann, H.5    Stacher-Janotta, G.6    Weber, U.7
  • 34
  • 35
    • 0021953850 scopus 로고
    • Effect of metoclopramide on gastric liquid emptying in patients with diabetic gastroparesis
    • Schade RR, Dugas MC, Lhotsky DM, Gavaler JS, Van Thiel DH: Effect of metoclopramide on gastric liquid emptying in patients with diabetic gastroparesis. Dig Dis Sci 30:10-15, 1985
    • (1985) Dig Dis Sci , vol.30 , pp. 10-15
    • Schade, R.R.1    Dugas, M.C.2    Lhotsky, D.M.3    Gavaler, J.S.4    Van Thiel, D.H.5
  • 36
    • 0021959928 scopus 로고
    • Acute and chronic effects of domperidone on gastric emptying in diabetic autonomic neuropathy
    • Horowitz M, Harding PE, Chatterton BE, Collins PJ, Shearman DJ: Acute and chronic effects of domperidone on gastric emptying in diabetic autonomic neuropathy. Dig Dis Sci 30:1-9, 1985
    • (1985) Dig Dis Sci , vol.30 , pp. 1-9
    • Horowitz, M.1    Harding, P.E.2    Chatterton, B.E.3    Collins, P.J.4    Shearman, D.J.5
  • 37
    • 0024239598 scopus 로고
    • Cisapride. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use as a prokinetic agent in gastrointestinal motility disorders
    • McCallum RW, Prakash C, Campoli-Richards DM, Goa KL: Cisapride. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use as a prokinetic agent in gastrointestinal motility disorders. Drugs 36:652-681, 1988
    • (1988) Drugs , vol.36 , pp. 652-681
    • McCallum, R.W.1    Prakash, C.2    Campoli-Richards, D.M.3    Goa, K.L.4
  • 41
    • 0031767175 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow
    • Wettergren A, Wojdemann M, Holst JJ: Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow. Am J Physiol 275:G984-G992, 1998
    • (1998) Am J Physiol , vol.275
    • Wettergren, A.1    Wojdemann, M.2    Holst, J.J.3
  • 42
    • 0031964826 scopus 로고    scopus 로고
    • Mechanisms of the antidiabetic action of subcutaneous glucagon-like peptide-1 (7-36)amide in non-insulin dependent diabetes mellitus
    • Schirra J, Leicht P, Hildebrand P, Beglinger C, Arnold R, Göke B, Katschinski M: Mechanisms of the antidiabetic action of subcutaneous glucagon-like peptide-1 (7-36)amide in non-insulin dependent diabetes mellitus. J Endocrinol 156:177-186, 1998
    • (1998) J Endocrinol , vol.156 , pp. 177-186
    • Schirra, J.1    Leicht, P.2    Hildebrand, P.3    Beglinger, C.4    Arnold, R.5    Göke, B.6    Katschinski, M.7
  • 43
    • 0029074964 scopus 로고
    • Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers: Dose-response-relationships
    • Ritzel R, Ørskov C, Holst JJ, Nauck MA: Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers: dose-response-relationships. Diabetologia 38:720-725, 1995
    • (1995) Diabetologia , vol.38 , pp. 720-725
    • Ritzel, R.1    Ørskov, C.2    Holst, J.J.3    Nauck, M.A.4
  • 44
    • 0037850667 scopus 로고    scopus 로고
    • Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes
    • Fineman MS, Bicsak TA, Shen LZ, Taylor K, Gaines E, Varns A, Kim D, Baron AD: Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes. Diabetes Care 26:2370-2377, 2003
    • (2003) Diabetes Care , vol.26 , pp. 2370-2377
    • Fineman, M.S.1    Bicsak, T.A.2    Shen, L.Z.3    Taylor, K.4    Gaines, E.5    Varns, A.6    Kim, D.7    Baron, A.D.8
  • 45
    • 3042617876 scopus 로고    scopus 로고
    • The potential role of glucagon-like peptide 1 in diabetes
    • Meier JJ, Nauck MA: The potential role of glucagon-like peptide 1 in diabetes. Curr Opin Investig Drugs 5:402-410, 2004
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 402-410
    • Meier, J.J.1    Nauck, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.