Natural disruption of group 2 phospholipase A2 gene protects against choline-deficient ethionine-supplemented diet-induced acute pancreatitis and lung injury

Pancreas

Volumn 31, Issue 1, 2005, Pages 48-53

  Kihara, Yasuyuki ^a   Yoshikawa, Hiroyuki ^a   Honda, Hidekazu ^a   Fukumitsu, Ken Ichirou ^a   Yamaguchi, Taizou ^a   Otsuki, Makoto ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Acute pancreatitis; Group 2 phospholipase A2; Lung injury

Indexed keywords

AMYLASE; CHOLINE; ETHIONINE; MYELOPEROXIDASE; PHOSPHOLIPASE A2;

ACUTE PANCREATITIS; AMYLASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DISEASE ACTIVITY; DISEASE EXACERBATION; DISEASE SEVERITY; ENZYME ACTIVITY; FEMALE; GENE; GENE DISRUPTION; HISTOPATHOLOGY; INFLAMMATORY CELL; KNOCKOUT MOUSE; LUNG ALVEOLUS; LUNG INJURY; MOUSE; MULTIPLE ORGAN FAILURE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SURVIVAL; SURVIVAL TIME; WILD TYPE;

ACUTE DISEASE; AMYLASES; ANIMALS; CHOLINE DEFICIENCY; DIETARY SUPPLEMENTS; DUODENUM; ETHIONINE; FEMALE; LUNG; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; PANCREAS; PANCREATITIS; PHOSPHOLIPASES A; RNA, MESSENGER;

EID: 21344450052     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mpa.0000168223.43709.28     Document Type: Article

References (26)

1. Dennis EA. Diversity of group types, regulation, and function of phospholipase A2. J Biol Chem. 1994;269:13057-13060.
2. Nevalainen TJ. Serum phospholipases A2 in inflammatory diseases. Clin Chem. 1993;39:2453-2459.
3. Tcholakov O, Uhl W, Schmitter N, et al. Role of phospholipase A2 in acute pancreatitis. Acute pancreatitis. In: Büchler MW, Uhl W, Friess H, Malfertheiner P, eds. Novel Concepts in Biology and Therapy. Berlin, Germany: Blackwell Science; 1999:109-119.
4. Büchler MW, Malfertheiner P, Schädlich H, et al. Role of phospholipase A2 in human acute pancreatitis. Gastroenterology. 1989;97:1521-1526.
5. Grönroos JM, Nevalainen TJ. Increased concentrations of synovial-type phospholipase A2 in serum and pulmonary and renal complications in acute pancreatitis. Digestion. 1992;52:232-236.
6. Kennedy BP, Payette P, Mudgett J, et al. A natural disruption of the secretory group 11 phospholipase A2 gene in inbred mouse strains. J Biol Chem. 1995;270:22378-22385.
7. Lombardi B, Estes LW, Longnecker DS. Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am J Pathol 1975;79:465-480.
8. Higashino K, Ishizaki J, Kishino J, et al. Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals. Eur J Biochem. 1994;225:375-382.
9. Ishizaki J, Suzuki N, Higashino K, et al. Cloning and characterization of novel mouse and human secretory phospholipase A2s. J Biol Chem. 1999;274:24973-24979.
10. Korc M, Chandrasekar B, Yamanaka Y, et al. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha. J Clin Invest. 1992;90:1352-1367.
11. Davidson FF, Dennis EA, Powell M, et al. Inhibition of phospholipase A2 by "lipocortins" and calpactins. An effect of binding to substrate phospholipids. J Biol Chem. 1987;262:1698-1705.
12. Furue S, Hori Y, Kuwabara K, et al. Increased activity of group II phospholipase A2 in plasma in rat sodium deoxycholate induced acute pancreatitis. Gut. 1997;41:826-831.
13. Yamanaka K, Saluja AK, Brown GE, et al. Protective effects of prostaglandin E1 on acute lung injury of caerulein-induced acute pancreatitis in rats. Am J Physiol. 1997;272:G23-G30.
14. Grönroos JM, Hietaranta AJ, Nevalainen TJ. Renal tubular cell injury and serum phospholipase A2 activity in acute pancreatitis. Br J Surg. 1992;79:800-801.
15. Nevalainen TJ, Grönroos JM, Kortesuo PT. Pancreatic and synovial type phospholipases A2 in serum samples from patients with severe acute pancreatitis. Gut. 1993;34:1133-1136.
16. Uhl W, Schrag HJ, Schmitter N, et al. Pathophysiological role of secretory type I and II phospholipase A2 in acute pancreatitis: an experimental study in rats. Gut. 1997;40:386-392.
17. Uhl W, Schrag HJ, Schmitter N, et al. Experimental study of a novel phospholipase A2 inhibitor in acute pancreatitis. Br J Surg. 1998;85:618-623.
18. Nevalainen TJ, Hietaranta AJ, Grönroos JM. Phospholipase A2 in acute pancreatitis: new biochemical and pathological aspects. Hepatogastroenterology. 1999;46:2731-2735.
19. Hietaranta AJ, Laszik ZG, Aho HJ, et al. The role of phospholipase A2 in pancreatic acinar cell injury. Int J Pancreatol. 1991;8:187-201.
20. Yoshikawa T, Naruse S, Kitagawa M, et al. Effect of a new inhibitor of type II phospholipase A2 on experimental acute pancreatitis in rats. Pancreas. 1999;19:193-198.
21. Manabe T, Steer ML. Protease inhibitors and experimental acute hemorrhagic pancreatitis. Ann Surg. 1979;190:13-17.
22. Mayer JM, Laine VJO, Kolodziej S, et al. Acute pancreatitis in transgenic mice expressing human group UA phospholipase A2. Pancreas. 2002;25:188-191.
23. Nyman KM, Uhl W, Forsström J, et al. Serum phospholipase A2 in patients with multiple organ failure. J Surg Res. 1996;60:7-14.
24. Hietaranta A, Kemppainen E, Puolakkainen P, et al. Extracellular phospholipases A2 in relation to systemic inflammatory response syndrome (SIRS) and systemic complications in severe acute pancreatitis. Pancreas. 1999;18:385-391.
25. Arbibe L, Koumanov K, Vial D, et al. Generation of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interaction. J Clin Invest. 1998;102:1152-1160.
26. Tsukahara Y, Morisaki T, Horita Y, et al. Phospholipase A2 mediates nitric oxide production by alveolar macrophages and acute lung injury in pancreatitis. Ann Surg. 1999;229:385-392.