Pathophysiological role of secretory type I and II phospholipase A2 in acute pancreatitis: An experimental study in rats

Gut

Volumn 40, Issue 3, 1997, Pages 386-392

  Uhl, W ^a   Schrag, H J ^a   Schmitter, N ^a   Nevalainen, T J ^b   Aufenanger, J ^c   Wheatley, A M ^a   Buchler M W ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF MANNHEIM   (Germany)

Author keywords

acute pancreatitis; cerulein pancreatitis; phospholipase A2; prognosis; sodium taurocholate pancreatitis

Indexed keywords

CERULETIDE; PHOSPHOLIPASE A2; TAUROCHOLIC ACID;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ARTICLE; CATALYSIS; ENZYME ACTIVITY; FEMALE; HISTOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

EID: 0030987126     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.40.3.386     Document Type: Article

References (38)

1. Dennis EA. Phospholipase A2 mechanism: inhibition and role in arachidonic acid release. Drug Development Research 1987; 10: 205-20.
2. Green JA, Smith GM, Buchta R, Lee R, Ho KY, Rajkovic IA, et al. Circulating phospholipase A2 activity associated with sepsis and septic shock is indistinguishable from that associated with rheumatoid arthritis. Inflammation 1991; 15: 355-67.
3. Vadas P. Elevated plasma phospholipase A2 levels: correlation with hemodynamic and pulmonary changes in gram-negative septic shock. J Lab Clin Med 1984; 104: 873-81.
4. Vadas P, Pruzanski W. Biology of disease: role of secretory phospholipase A2 in the pathobiology of diseases. Lab Invest 1986; 55: 391-404.
5. Pruzanski W, Vadas P, Stefanski E, Urowitz MB. Phospholipase A2 activity in sera and synovial fluids in rheumatoid arthritis. J Rheumatol 1985; 12: 211-6.
6. Büchler M, Malfertheiner P, Schädlich H, Nevalainen TJ, Friess H, Beger HG. Role of phospholipase A2 in human acute pancreatitis. Gastroenterology 1989; 97: 1521-6.
7. Nevalainen TJ, Eskola JU, Aho AJ, Havia VT, Lövgren TNE, Näntö V. Immunoreactive phospholipase A3 in serum in acute pancreatitis and pancreatic cancer. Clin Chem 1985; 31: 1116-20.
8. Uhl W, Beger HG, Hoffmann G, Hanisch E, Schild A, Waydhas Ch, et al. Phospholipase A2 in intensive care patients: A multicentric study. J Am Coll Surg 1995; 180: 323-31.
9. Uhl W, Büchler MH, Nevalainen TJ, Deller A, Beger HG. Serum phospholipase A2 in patients with multiple injuries. J Trauma 1990; 30: 1285-90.
10. Schröder T, Lempinen E, Kiviaakso E, Nikki P. Serum phospholipase A2 and pulmonary changes in acute fulminant pancreatitis. Resuscitation 1982; 10: 79-87.
11. Dennis AE. Diversity of group types, regulation, and function of phospholipase A2. J Biol Chem 1994; 269: 13057-60.
12. Funatomi H, Hatta Y. Studies on heat stability of phospholipase A2 in human serum. Jpn J Gastroenterol 1991; 88: 71-6.
13. Kozumplik V, Staffa F, Hoffmann GE. Purification of pancreatic phospholipase A2 from human duodenal juice. Biochim Biophys Acta 1989; 1002: 395-7.
14. Scott D, Sigler B. Structure and catalytic mechanism of secretory phospholipase A2. Advances Prot Chem 1994; 45: 53-88.
15. Nevalainen TJ, Eskola JU. Time-resolved fluoroimmunoassay of pancreatic phospholipase A2. Klin Wochenschr 1989; 67: 103-5.
16. Nevalainen TJ, Kortesuo PT, Rintala E, Märki F. Immunochemical detection of group I and II phospholipase A2 in human serum. Clin Chem 1992; 38: 1824-9.
17. Nishijima J, Okamoto M, Ogawa M, Kasaki G, Yamano T. Purification and characterization of human pancreatic phospholipase A2 in development of a radioimmunoassay. J Biochem 1983; 94: 137-47.
18. Aufenanger J, Zimmer W, Kattermann R. Characteristics of a radiometric E coli-based phospholipase A2 assay modified method for clinical applications. Clin Chem 1993; 39: 506-13.
19. Hoffmann GE, Neumann U. Modified photometric method for the determination of phospholipase A activities. Klin Wochenschr 1989; 67: 106-9.
20. Eskola JU, Nevalainen TJ, Kortesuo P. Immunoreactive pancreatic phospholipase A2 and catalytically active PLA2 in serum from patients with acute pancreatitis. Clin Chem 1988; 34: 1052-4.
21. Mäkelä A, Sternby B, Kunsi T, Puolakkainen P, Schröder T. Phospholipase A2 activity and concentration in several body fluids in patients with acute pancreatitis. Scand J Gastroenterol 1990; 25: 944-50.
22. Adler G, Rohr G, Kern HF. Alteration of membrane fusion as a cause of acute pancreatitis in the rat. Dig Dis Sci 1982; 27: 993-1002.
23. Van Dongen JJ, Remie R, Rensema JW, Van Wunnik GHJ, eds. Manual of microsurgery on the laboratory rat. Amsterdam, New York: Elsevier 1990; 95-100, 159-69.
24. Aho HJ, Koskensalo SML, Nevalainen TJ. Experimental pancreatitis in the rat. Sodium taurocholate-induced acute haemorrhagic pancreatitis. Scand J Gastroenterol 1980; 15: 411-6.
25. Hietaranta AJ, Aho HJ, Nevalainen TJ. Pancreatic phospholipase A2 in cerulein-induced acute pancreatitis in the rat. Im J Pancreatol 1993; 14: 261-7.
26. Kortesuo PT, Hietaranta AJ, Jämiä M, Hirsimäki P, Nevalainen TJ. Rat pancreatic phospholipase A2: purification, localization and development of an immunoassay. Int J Pancreatol 1993; 13: 111-8.
27. Aufenanger J, Püttann M, Samman M, Zimmer W, Scheuer W, Kattermann R. Aktive Pankreas-Phospholipase A2 als prognostischer Marker der akuten Pankreatitis. GTI Labor Medizin 1993; 16: 266-8.
28. Spormann H, Sokolowski A, Letko G. Effect of temporary ischemia upon development and histological patterns of acute pancreatitis in the rat. Pathol Res Pract 1989; 184: 507-13.
29. Hietaranta AJ, Aho HJ, Grönroos JM, Hua ZY, Nevalainen TJ. Pancreatic phospholipase A2 in proximal tubules of rat kidney in experimental acute pancreatitis and after intravenous injection of the enzyme. Pancreas 1992; 7: 326-33.
30. Lampel M, Kern HF. Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue. Virchows Arch 1977; 373: 97-117.
31. Myren J. Acute pancreatitis. Pathogenetic factors as a basis for treatment. Scand J Gastroenterol 1977; 12: 513-7.
32. Mayer AD, Airey M, Hodgson J, McMahon MJ. Enzyme transfer from pancreas to plasma during acute pancreatitis. The contribution of ascitic fluid and lymphatic drainage of the pancreas. Gut 1985; 26: 876-81.
33. Lange JF, Beyaert PJ, van Vugt H, Tytgat GNJ, van Gool J. Pathways of enzyme transfer in sodium taurocholate induced acute hemorrhagic pancreatitis. Digestion 1986; 35: 229-36.
34. Nevalainen TJ, Grönroos JM, Kortesuo PT. Pancreatic and synovial-type phospholipases A2 in serum in severe acute pancreatitis. Gut 1993; 34: 1133-6.
35. Kawai H, Ozawa S, Funatomi H, Hatta Y. Serum and ascitic phospholipase A2 activities and their heat stabilities in taurocholate induced rat acute pancreatitis. Jpn J Gastroenterol 1991; 88: 2847-52.
36. Nordback I, Teerenhovi O, Auvinen O, Koivula T, Thuren T, Kinnunen P, et al. Human pancreatic phospholipase A2 in acute necrotizing pancreatitis. Digestion 1989; 42: 128-34.
37. Aho HJ, Nevalainen TJ, Lindberg RLP, Aho AJ. Experimental pancreatitis in the rat. The role of phospholipase A in sodium taurocholate-induced acute haemorrhagic pancreatitis. Scand J Gastroenterol 1980; 15: 1027-31.
38. Abita JP, Lazdunski M, Bonsem PPM, Pieterson WA, De Haas GH. Zymogene-enzyme transformations on the mechanism of activation of phospholipase A. Eur J Biochem 1972; 30: 37-47.