Metabolism of osaterone acetate in dogs and humans

Steroids

Volumn 70, Issue 9, 2005, Pages 563-572

  Minato, Kouichi ^a   Honma, Seijirou ^a   Shinohara, Yoshihiko ^b   Hashimoto, Takao ^b  

^a Grelan Pharmaceutical Co   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

11 Hydroxylation; 11 HSD; Cytochrome P450; Drug metabolism; Osaterone acetate; Species differences

Indexed keywords

17ALPHA ACETOXY 6 CHLORO 11BETA HYDROXY 2 OXA 4,6 PREGNADIENE 3,20 DIONE; 17ALPHA ACETOXY 6 CHLORO 15BETA HYDROXY 2 OXA 4,6 PREGNADIENE 3,20 DIONE; 17ALPHA ACETOXY 6 CHLORO 15BETA,21 DIHYDROXY 2 OXA 4,6 PREGNADIENE 3,20 DIONE; 17ALPHA ACETOXY 6 CHLORO 2 OXA 4,6 PREGNADIENE 3,11,20 TRIONE; 17ALPHA ACETOXY 6 CHLORO 21 HYDROXY 2 OXA 4,6 PREGNADIENE 3,20 DIONE; 17ALPHA ACETOXY 6BETA,21 DIHYDROXY 2 OXA 4 PREGNENE 3,20 DIONE; 21 ACETOXY 6 CHLORO 17ALPHA HYDROXY 2 OXA 4,6 PREGNADIENE 3,20 DIONE; 6 CHLORO 17ALPHA 2 OXA 4,6 PREGNADIENE 3,20 DIONE; 6 CHLORO 17ALPHA,21 DIHYDROXY 2 OXA 4,6 PREGNADIENE 3,20 DIONE; 6BETA,15BETA,17ALPHA,20 TETRAHYDROXY 2 OXA 4 PREGNEN 3 ONE; 6BETA,17ALPHA,21 TRIHYDROXY 2 OXA 4 PREGNENE 3,20 DIONE; DRUG METABOLITE; OSATERONE ACETATE; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; CHLORINATION; CONTROLLED STUDY; DEACETYLATION; DRUG BLOOD LEVEL; DRUG FECES LEVEL; DRUG HALF LIFE; DRUG METABOLISM; DRUG URINE LEVEL; FECES LEVEL; HORMONE BLOOD LEVEL; HORMONE METABOLISM; HORMONE URINE LEVEL; HUMAN; HYDROXYLATION; MALE; NONHUMAN; NORMAL HUMAN; SPECIES DIFFERENCE;

ACETYLATION; ADMINISTRATION, ORAL; ANDROGEN ANTAGONISTS; ANIMALS; CHLORMADINONE ACETATE; DOGS; FECES; HUMANS; HYDROXYLATION; MOLECULAR STRUCTURE; SPECIES SPECIFICITY; STEROIDS, CHLORINATED;

CANIS FAMILIARIS;

EID: 21344449306     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2005.03.012     Document Type: Article

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