Attribution of the various inhibitory actions of the Streptococcal Inhibitor of Complement (SIC) to regions within the molecule

Journal of Biological Chemistry

Volumn 280, Issue 20, 2005, Pages 20120-20125

  Binks, Michael J ^a   Fernie King, Barbara A ^b   Seilly, David J ^b   Lachmann, Peter J ^b   Sriprakash, Kadaba S ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; DNA; ENZYMES; MOLECULAR WEIGHT; POLYPEPTIDES;

LOW REPEAT REGION (LRR); PROLINE-REACH REGION (PRR); SHORT REPEAT REGION (SRR); STREPTOCOCCAL INHIBITOR OF COMPLEMENT (SIC);

GENES;

BETA DEFENSIN; COMPLEMENT INHIBITOR; LYSOZYME; PEPTIDE; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; STREPTOCOCCAL INHIBITOR OF COMPLEMENT; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BETA DEFENSIN 3; BETA-DEFENSIN 3; CYTOSKELETON PROTEIN; EZRIN; PEPTIDE FRAGMENT; PHOSPHOPROTEIN; RECOMBINANT PROTEIN; SIC PROTEIN, STREPTOCOCCUS;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CYTOLYSIS; CYTOSKELETON; ENZYME INHIBITION; HOST RESISTANCE; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STREPTOCOCCUS PYOGENES; ANIMAL; BACTERIAL GENE; BINDING SITE; CHEMISTRY; CHICKEN; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; IN VITRO STUDY; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

STREPTOCOCCUS PYOGENES;

ANIMALS; BACTERIAL PROTEINS; BETA-DEFENSINS; BINDING SITES; CHICKENS; COMPLEMENT INACTIVATOR PROTEINS; CYTOSKELETAL PROTEINS; GENES, BACTERIAL; HUMANS; MURAMIDASE; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STREPTOCOCCUS PYOGENES;

EID: 21244506198     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414194200     Document Type: Article

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