Distribution of streptococcal inhibitor of complement variants in pharyngitis and invasive isolates in an epidemic of serotype M1 group A Streptococcus infection

Journal of Infectious Diseases

Volumn 183, Issue 4, 2001, Pages 633-639

  Hoe, Nancy P ^a   Vuopio Varkila, Jaana ^b   Vaara, Martti ^b,c   Grigsby, Diana ^d,f,g   De Lorenzo, David ^e   Fu, Yun Xin ^e   Dou, Shu Jun ^d   Pan, Xi ^d   Nakashima, Kazumitsu ^d,f,g   Musser, James M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF TEXAS   (United States)

^f BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^g CHUBU NATIONAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; COMPLEMENT INHIBITOR; DNA;

ARTICLE; BACTERIAL INFECTION; BACTERIUM ISOLATE; COMPLEMENT SYSTEM; EPIDEMIC; NONHUMAN; NUCLEOTIDE SEQUENCE; PHARYNGITIS; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEROTYPE; STREPTOCOCCUS INFECTION;

ALLELES; AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; BACTEREMIA; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; CARRIER PROTEINS; COMPLEMENT INACTIVATOR PROTEINS; DISEASE OUTBREAKS; FINLAND; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MOLECULAR SEQUENCE DATA; PHARYNGITIS; PHYLOGENY; POPULATION SURVEILLANCE; SEROTYPING; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; VIRULENCE;

EID: 0035865911     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/318543     Document Type: Article

References (30)

1. Hypervariability generated by natural selection in an extracellular complement-inhibiting protein of serotype M1 strains of group A Streptococcus
2. Rapid selection of complement-inhibiting protein variants in group A Streptococcus epidemic waves
3. Protein SIC, a novel extracellular protein of Streptococcus pyogenes interfering with complement function
4. Human immune response to streptococcal inhibitor of complement, a serotype M1 group A Streptococcus extracellular protein involved in epidemics
5. Nonpolar inactivation of the hypervariable streptococcal inhibitor of complement gene (sic) in serotype M1 Streptococcus pyogenes significantly decreases mouse mucosal colonization
6. Genetic diversity and relationships among Streptococcus pyogenes strains expressing serotype M1 protein: Recent intercontinental spread of a subclone causing episodes of invasive disease
7. Characterization of group A Streptococcus strains recovered from Mexican children with pharyngitis by automated DNA sequencing of virulence-related genes: Unexpectedly large variation in the gene (sic) encoding a complement-inhibiting protein
8. On the problem of discovering the most parsimonious trees
9. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
10. Statistical properties of segregating sites
11. An outbreak of invasive group A streptococcal disease associated with high carriage rates of the invasive clone among school-aged children
12. Invasive group A streptococcal infections in North Carolina: Epidemiology, clinical features, and genetic and serotype analysis of causative organisms
13. Real-time molecular epidemiologic analysis of an outbreak of Streptococcus pyogenes invasive disease in US Air Force trainees
14. Molecular comparison of group A streptococci of T1M1 serotype from invasive and non-invasive infections in Finland
15. Clonal diversity of Neisseria meningitidis from a population of asymptomatic carriers
16. Asymptomatic carriage of Neisseria meningitidis in a randomly sampled population
17. Meningococcal carriage in relation to an outbreak of invasive disease due to Neisseria meningitidis serogroup C in the Netherlands
18. Nucleotide substitutions and small-scale insertion produce size and antigenic variation in group A streptococcal M1 protein
19. Rapid molecular genetic subtyping of serotype M1 group A Streptococcus strains
20. Variable susceptibility to opsonophagocytosis of group A Streptococcus M-1 strains by human immune sera
21. Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus
22. A response regulator that represses transcription of several virulence operons in the group A Streptococcus
23. A two-component regulatory system, CsrR-CsrS, represses expression of three Streptococcus pyogenes virulence factors, hyaluronic acid capsule, streptolysin S, and pyrogenic exotoxin B
24. Characterization of a two-component system in Streptococcus pyogenes which is involved in regulation of hyaluronic acid production
25. Characterization of a mouse-passaged, highly encapsulated variant of group A Streptococcus in in vitro and in vivo studies
26. Mutation in csrR global regulator reduces Streptococcus pyogenes internalization