Mesenchymal stem cells rescue CD34+ cells from radiation-induced apoptosis and sustain hematopoietic reconstitution after coculture and cografting in lethally irradiated baboons: Is autologous stem cell therapy in nuclear accident settings hype or reality?

Bone Marrow Transplantation

Volumn 35, Issue 12, 2005, Pages 1201-1209

  Drouet, Michel ^a   Mourcin, F ^a   Grenier, N ^a   Delaunay, C ^a   Mayol, J F ^a   Lataillade, J J ^b   Peinnequin, A ^a   Herodin F ^a  

^a CENTRE DE RECHERCHES   (France)

^b Centre de Transfusion Sanguine des Armees   (France)

Author keywords

Cytokine; Ex vivo expansion; Irradiation; Mesenchymal stem cell; Nonhuman primate

Indexed keywords

AMPICILLIN; CD34 ANTIGEN; CYCLOPHOSPHAMIDE; CYTOKINE; GENTAMICIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; BABOON; BONE MARROW DISEASE; CELL COUNT; CELL CULTURE; CELL DAMAGE; CELL GROWTH; CELL ISOLATION; CELL LINEAGE; CELL MANIPULATION; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; EX VIVO STUDY; EXPERIMENTAL MODEL; GRAFT INFECTION; GRAFT SURVIVAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IN VITRO STUDY; LEUKAPHERESIS; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; NONHUMAN; NUCLEAR ACCIDENT; PRIORITY JOURNAL; RADIATION INJURY; STEM CELL MOBILIZATION; THROMBOCYTE; TREATMENT OUTCOME; WHOLE BODY RADIATION;

ACCIDENTS, RADIATION; ANIMALS; ANTIGENS, CD34; APOPTOSIS; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; COCULTURE TECHNIQUES; GRAFT SURVIVAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MODELS, ANIMAL; PAPIO; RADIATION INJURIES; STEM CELL TRANSPLANTATION; TRANSPLANTATION, AUTOLOGOUS; WHOLE-BODY IRRADIATION;

EID: 21244434706     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704970     Document Type: Article

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