The effect of ergosterol on dipalmitoylphosphatidylcholine bilayers: A deuterium NMR and calorimetric study

Biophysical Journal

Volumn 88, Issue 3, 2005, Pages 1799-1808

  Hsueh, Ya Wei ^a,d   Gilbert, Kyle ^a,e   Trandum, C ^b,c   Zuckermann, M ^a   Thewalt, Jenifer ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c ROSKILDE UNIVERSITY   (Denmark)

^d NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DEUTERIUM; DIPALMITOYLPHOSPHATIDYLCHOLINE; ERGOSTEROL; PHOSPHOLIPID; STEROL; DIMYRISTOYLPHOSPHATIDYLCHOLINE;

ARTICLE; CALORIMETRY; CELL MEMBRANE; DEUTERON NUCLEAR MAGNETIC RESONANCE; DIFFERENTIAL SCANNING CALORIMETRY; FUNGAL CELL; LIPID BILAYER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SACCHAROMYCES CEREVISIAE; CHEMISTRY; CONFORMATION; MEMBRANE FLUIDITY; PHASE TRANSITION; SOLUTION AND SOLUBILITY; TEMPERATURE;

CALORIMETRY, DIFFERENTIAL SCANNING; DEUTERIUM; DIMYRISTOYLPHOSPHATIDYLCHOLINE; ERGOSTEROL; LIPID BILAYERS; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE FLUIDITY; MOLECULAR CONFORMATION; PHASE TRANSITION; SOLUTIONS; TEMPERATURE;

EID: 21144453569     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.104.051375     Document Type: Article

References (29)

1. Bagnat, M., A, Chang, and K. Simons. 2001. Plasma membrane proton ATPase Pma1p requires raft association for surface delivery in yeast. Mol. Biol. Cell. 12:4129-4138.
2. Bagnat, M., S. Keranen, A. Shevchenko, and K. Simons. 2000. Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. Proc. Nat. Acad. Sci. USA 97:3254-3259.
3. Bottema, C. D. K., R. J. Rodriguez, and L. W. Parks. 1985. Influence of sterol structure on yeast plasma membrane properties. Biochim. Biophys. Acta. 813:313-320.
4. Carrington, A., and A. D. McLachlan. 1967. Introduction to Magnetic Resonance. Harper & Row, New York, NY.
5. Davis, J. H., K. R. Jeffrey, M. Bloom, M. I. Valic, and T. P. Higgs. 1976. Quadrupolar echo deuteron magnetic resonance spectroscopy in ordered hydrocarbon chains. Chem. Phys. Lett. 42:390-394.
6. Eisenkolb, M., C. Zenzmaier, E. Leitner, and R. Schneller. 2002. A specific structural requirement for ergosterol in long chain fatty acid synthesis mutants important for maintaining raft domains in yeast. Mol. Biol. Cell. 13:4414-4428.
7. Endress, E., S. Bayerl, K. Prechtel, C. Maier, R. Merkel, and T. M. Bayerl. 2002. The effect of cholesterol, lanosterol, and ergosterol on lecithin bilayer mechanical properties at molecular and microscopic dimensions: a solid-state NMR and micropipet study. Langmuir. 18:3293-3299.
8. Filippov, A., G. Orädd, and G. Lindblom. 2003. The effect of cholesterol on the lateral diffusion of phospholipids in oriented bilayers. Biophys. J. 84:3079-3086.
9. 2H nuclear magnetic resonance study of phosphatidylcholine/cholesterol interactions: characterization of liquid-gel phases. Biochemistry. 32:13277-13287.
10. Ipsen, J. H., G. Karlstrom, O. G. Mouritsen, H. Wennerstrom, and M. J. Zuckermann. 1987. Phase-equilibria in the phosphatidylcholine-cholesterol system. Biochim. Biophys. Acta. 905:162-172.
11. Kuebler, E., H. G. Dohlman, and M. P. Lisanti. 1996. Identification of Triton X-100 insoluble membrane domains in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 271:32975-32980.
12. Kusumi, A., I. Koyama-Honda, and K. Suzuki. 2004. Molecular dynamics and interactions for creation of stimulation-induced stabilized rafts from small unstable steady-state rafts. Traffic. 5:213-230.
13. 2H-nuclear magnetic resonance. Biophys. J. 56:1037-1041.
14. Longley, R. P., A. H. Rose, and B. A. Knights. 1968. Composition of the protoplast membrane from Saccharomyces cerevisiae. Biochem. J. 108: 401-412.
15. Ohvo-Rekilä, H., B. Ramstedt, P. Leppimaki, and J. P. Slotte. 2002. Cholesterol interactions with phospholipids in membranes. Prog. Lipid Res. 41:66-97.
16. Patton, J. L., and R. L. Lester. 1991. The phosphoinositol sphingolipids of Saccharomyces cerevisiae are highly localized in the plasma membrane. J. Bacteriol. 173:3101-3108.
17. Rodriguez, R. J., C. Low, C. D. Bottema, and L. W. Parks. 1985. Multiple functions for sterols in Saccharomyces cerevisiae. Biochim. Biophys. Acta. 837:336-343.
18. Schneller, R., B. Brügger, R. Sandhoff, G. Zellnig, A. Leber, M. Lampl, K. Athenstaedt, C. Hrastnik, S. Eder, G. Daum, F. Paltauf, F. T. Wieland, and S. D. Kohlwein. 1999. Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membrane. J. Cell Biol. 146:741-754.
19. Smondyrev, A. M., and M. L. Berkowitz. 2001. Molecular dynamics simulation of the structure of dimyristoylphosphatidylcholine bilayers with cholesterol, ergosterol, and lanosterol. Biophys. J. 80:1649-1658.
20. Thewalt, J. L., and M. Bloom. 1992. Phosphatidylcholine: cholesterol phase diagrams. Biophys. J. 63:1176-1181.
21. Tuller, G., T. Nemec, C. Hrastnik, and G. Daum. 1999. Lipid composition of subcellular membranes of an FY1679-derived haploid yeast wild-type strain grown on different carbon sources. Yeast. 15:1555-1564.
22. 31P-NMR spectroscopy. Biochim. Biophys. Acta. 1238:163-176.
23. Varma, R., and S. Mayor. 1998. GPI-anchored proteins are organized in submicron domains at the cell surface. Nature. 394:798-801.
24. Veatch, S., and S. Keller. 2003. Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol. Biophys. J. 85: 3074-3083.
25. Veatch, S. L., I. V. Polozov, K. Gawrisch, and S. L. Keiler. 2004. Liquid domains in vesicles investigated by NMR and fluorescence microscopy. Biophys. J. 86:2910-2922.
26. 2H nuclear magnetic resonance and differential scanning calorimetry. Biochemistry. 29:451-464.
27. Xu, X., R. Bittman, G. Duportail, D. Heissler, C. Vilcheze, and E. London. 2001. Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid/sterol domains (rafts). Comparison of cholesterol to plant, fungal, and disease-associated sterols and comparison of sphingomyelin, cerebrosides, and ceramide. J. Biol. Chem. 276: 33540-33546.
28. Zinser, E., F. Paltauf, and G. Daum. 1993. Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterot metabolism. J. Bacteriol. 175:2853-2858.
29. Zinser, E., C. D. Sperka-Gottlieb, E. V. Fasch, S. D. Kohlwein, F. Paltauf, and G. Daum. 1991. Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J. Bacteriol. 173:2026-2034.