Identification of a multixenobiotic resistance mechanism in primary cultured epidermal cells from Oncorhynchus mykiss and the effects of environmental complex mixtures on its activity

Aquatic Toxicology

Volumn 73, Issue 2, 2005, Pages 115-127

  Shúilleabháin, Sharon Ní ^a   Davoren, Maria ^a   Mothersill, Carmel ^b   Sheehan, David ^c   Hartl, Mark G J ^c   Kilemade, Michael ^c   O'Brien, Nora M ^c   O'Halloran, John ^c   Van Pelt, Frank N A M ^c   Lyng, Fiona M ^a  

^a DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Chemosensitisers; Confocal laser scanning microscopy; Immunocytochemistry; P glycoprotein; Rhodamine 123; Verapamil

Indexed keywords

EPITOPE; FLUORESCENT DYE; GLYCOPROTEIN P; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY JSB1; MULTIDRUG RESISTANCE PROTEIN 1; ORGANOCHLORINE PESTICIDE; POLYCHLORINATED BIPHENYL; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN; RHODAMINE 123; UNCLASSIFIED DRUG; VERAPAMIL;

PHYSIOLOGICAL RESPONSE; POLLUTION TOLERANCE; SALMONID; XENOBIOTICS;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL CULTURE; CONTAMINATION; CONTROLLED STUDY; CYTOPLASM; ENVIRONMENT; EPIDERMIS; EPIDERMIS CELL; EVALUATION; EXTRACT; FISH; FLUORESCENCE; IMMUNOCYTOCHEMISTRY; INHIBITION KINETICS; MODEL; MULTIXENOBIOTIC RESISTANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAINBOW TROUT; SAMPLE; SEDIMENT;

ANIMALS; CELLS, CULTURED; DRUG RESISTANCE, MULTIPLE; ENVIRONMENTAL POLLUTANTS; EPIDERMIS; GENE EXPRESSION REGULATION; GEOLOGIC SEDIMENTS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; ONCORHYNCHUS MYKISS; P-GLYCOPROTEINS; PROTEIN TRANSPORT; RHODAMINE 123; VERAPAMIL; XENOBIOTICS;

MAMMALIA; ONCORHYNCHUS MYKISS; SALMONIDAE; TELEOSTEI;

EID: 21144437256     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2005.03.014     Document Type: Article

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