A breakthrough in the ultrasensitive determination of small molecules: Noncompetitive immunoassays for haptens with an enhanced sensitivity

Japanese Journal of Clinical Chemistry

Volumn 33, Issue 2, 2004, Pages 90-100

  Kobayashi, Norihiro ^a   Goto, Junichi ^b  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EFLORNITHINE; HAPTEN;

ACCURACY; HETEROSANDWICH IMMUNOASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOASSAY; OPEN SANDWICH IMMUNOASSAY; PARTICLE SIZE; RADIOIMMUNOASSAY; REVIEW; SINGLE ANTIBODY IMMUNOMETRIC ASSAY; SOLID PHASE IMMOBILIZED EPITOPE IMMUNOASSAY;

EID: 21044448825     PISSN: 03705633     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (35)

1. Kobayashi N, Goto J: Noncompetitive immunoassays for small molecules with high sensitivity and specificity, Adv Clin Chem, 36: 139-170, 2001.
2. Mudgett-Hunter M, Anderson W, Haber E, Margolies MN: Binding and structural diversity among high-affinity monoclonal anti-digoxin antibodies, Mol Immunol, 22: 477-488, 1985.
3. Grassi J, et al.: Two different approaches for developing immunometric assays of haptens, Clin Chem, 42: 1532-1536, 1996.
4. Oguri H, et al.: Synthesis-based approach toward direct sandwich immunoassay for ciguatoxin CTX 3 C, J Am Chem Soc, 125: 7608-7612, 2003.
5. Valentine RC, Green NM: Electron microscopy of an antibody-hapten complex, J Mol Biol, 27: 615-617, 1967.
6. Ishikawa E, Hashida S, Kohno T, Hirota K: Ultrasensitive enzyme immunoassay, Clin Chim Acta, 194: 51-72, 1990.
7. Volland H, et al.: Enzyme immunometric assay for leukotriene C 4, J Immunol Methods, 175: 97-105, 1994.
8. Pradelles P, Grassi J, Créminon C, Boutten B, Mamas S: Immunometric assay of low molecular weight haptens containing primary amino groups, Anal Chem, 66: 16-22, 1994.
9. Buscarlet L, et al.: Cross-linking of 17 β-estradiol to monoclonal antibodies by direct UV irradiation: Application to an enzyme immunometric assay, Anal Chem, 71: 1002-1008, 1999.
10. Gunaratna PC, Wilson GS: Noncompetitive flow injection immunoassay for a hapten, α-(difluoromethyl) ornithine, Anal Chem, 65: 1152-1157, 1993.
11. Kara T, Nakamura K, Satomura S, Matsuura S: Noncompetitive immunoassay of thyroxine using a liquid-phase binding assay, Anal Chem, 66: 351-354, 1994.
12. Piran U, Riordan WJ, Livshin LA: New non-competitive immunoassays of small analytes, Clin Chem, 41: 986-990, 1995.
13. Giraudi G, Anfossi L, Rosso I, Baggiani C, Giovannoli C, Tozzi C: A general method to perform a noncompetitive immunoassay for small molecules, Anal Chem, 71: 4697-4700, 1999.
14. Jerne NK, Roland J, Cazenave P-A: Recurrent idiotopes and internal images, EMBO J, 1: 243-247 1982.
15. Barnard G, Kohen F: Idiometric assay: non-competitive immunoassay for small molecules typified by the measurement of estradiol in serum, Clin Chem, 36: 1945-1950, 1990.
16. Barnard G, et al.: The measurement of progesterone in serum by a non-competitive idiometric assay, Steroids, 60: 824-829, 1995.
17. Barnard G, Amir-Zaltsman Y, Lichter S, Gayer B, Kohen F: The measurement of oestrone-3-glucuronide in urine by non-competitive idiometric assay, J Steroid Biochem Mol Biol, 55: 107-114, 1995.
18. Kobayashi N, Oiwa H, Kubota K, Sakoda S, Goto J: Monoclonal antibodies generated against an affinity-labeled immune complex of an antibile acid metabolite antibody: an approach to noncompetitive hapten immunoassays based on anti-idiotype or anti-metatype antibodies, J Immunol Methods, 245: 95-108, 2000.
19. Kobayashi N, Kubota K, Oiwa H, Goto J, Niwa T, Kobayashi K: Idiotype-antiidiotype-based noncompetitive enzyme-linked immunosorbent assay of ursodeoxycholic acid 7-N-acetylglucosaminides in human urine with subfemtomole range sensitivity, J Immunol Methods, 272: 1-10, 2003.
20. Kobayashi N, et al.: Monoclonal anti-idiotype antibodies recognizing the variable region of a high-affinity antibody against 11-deoxycortisol. Production, characterization and application to a sensitive noncompetitive immunoassay, J Immunol Methods, 274: 63-75, 2003.
21. Voss Jr. EW, Miklasz SD, Petrossian A, Dombrink-Kurzman MA: Polyclonal antibodies specific for liganded active site (metatype) of a high affinity anti-hapten monoclonal antibody, Mol Immunol, 25: 751-759, 1988.
22. Voss Jr. EW, Mummert ME: Anti-metatype antibodies in immunoassays, Mikrochim Acta, 126: 193-202, 1997.
23. Ullman EF, et al.: Anti-immune complex antibodies enhance affinity and specificity of primary antibodies, Proc Natl Acad Sci USA, 90: 1184-1189, 1993.
24. Self CH, Dessi JL, Winger LA: High-performance assays of small molecules: enhanced sensitivity, rapidity, and convenience demonstrated with a noncompetitive immunometric anti-immune complex assay system for digoxin, Clin Chem, 40: 2035-2041, 1994.
25. Self CH, Dessi JL, Winger LA: Ultra-specific immunoassays for small molecules:roles of wash steps and multiple binding formats, Clin Chem, 42: 1527-1531, 1996.
26. Winger LA, Dessi JL, Self CH: Enhanced specificity for small molecules in a convenent format which removes a limitation of competitive immunoassay, J Immunol Methods, 199: 185-191, 1996.
27. Towbin H, Motz J, Oroszlan P, Zingel O: Sandwich immunoassay for the hapten angiotensin II. A novel assay principle based on antibodies against immune complexes, J Immunol Methods, 181: 167-176, 1995.
28. Nagata S, Tsutsumi T, Yoshida F, Ueno Y: A new type sandwich immunoassay for microcystin: production of monoclonal antibodies specific to the immune complex formed by microcystin and an anti-microcystin monoclonal antibody, Nat Toxins, 7: 49-55, 1999.
29. Suzuki C, Ueda H, Mahoney W, Nagamune T: Open sandwich enzyme-linked immunosorbent assay for the quantitation of small haptens, Anal Biochem, 286: 238-246, 2000.
30. Yokozeki T, Ueda H, Arai R, Mahoney W, Nagamune T: A homogeneous noncompetitive immunoassay for the detection of small haptens, Anal Chem, 74: 2500-2504, 2002.
31. Arbour NC, Ross TK, Zierold C, Prahl JM, DeLuca HFA highly sensitive method for large-scale measurement of 1, 25-dihydroxyvitamin D, Anal Biochem, 255: 148-154, 1988.
32. Edmunds JS, Fairey ER, Ramsdell JS: A rapid and sensitive high throughput reporter gene assay for estrogenic effects of environmental contaminants, Neurotoxicology, 18: 525-532, 1997.