A novel system to diagnose cutaneous adverse drug reactions employing the cellscan - Comparison with histamine releasing test and Inf-γ Releasing Test

Clinical and Developmental Immunology

Volumn 12, Issue 1, 2005, Pages 85-90

  Goldberg, Ilan ^a   Gilburd, Boris ^b   Kravitz, Martine Szyper ^b   Kivity, Shmuel ^a   Chaim, Berta Ben ^c   Klein, Tirza ^c   Schiffenbauer, Yael ^f   Trubniykovr, Ela ^f   Brenner, Sarah ^a   Shoenfeld, Yehuda ^b,d,e  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b Center for Autoimmune Diseases   (Israel)

^c RABIN MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

^e SHEBA MEDICAL CENTER   (Israel)

^f Chaim Sheba Medical Center ^*

Author keywords

Cytokines; Drug allergy; Histamine; Interferon releasing test; T cells

Indexed keywords

ACETYLSALICYLIC ACID; AMOXICILLIN; ATENOLOL; BENAZEPRIL; BROMOCRIPTINE; CEFUROXIME; CILAZAPRIL; COUMARIN; DIPYRONE; ENALAPRIL; FAMOTIDINE; FOSINOPRIL; GAMMA INTERFERON; HISTAMINE; HUMAN MENOPAUSAL GONADOTROPIN; IBUPROFEN; INDOMETACIN; METFORMIN; NIFEDIPINE; OFLOXACIN; PARACETAMOL; PHENAZOPYRIDINE; PHENYTOIN; PSEUDOEPHEDRINE; RAMIPRIL; ROFECOXIB; SIMVASTATIN; TIMOLOL; UNINDEXED DRUG; VALPROIC ACID;

ADULT; AGED; ARTICLE; CELL SELECTION; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG ERUPTION; DRUG EXPOSURE; FEMALE; HISTAMINE RELEASE; HUMAN; INTERMETHOD COMPARISON; LYMPHOCYTE; MALE; PRIORITY JOURNAL; SKIN MANIFESTATION; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; DIAGNOSTIC TEST; DRUG HYPERSENSITIVITY; IMMUNOLOGY; METHODOLOGY; MIDDLE AGED; SECRETION; SKIN DISEASE;

ADULT; AGED; AGED, 80 AND OVER; DIAGNOSTIC TESTS, ROUTINE; DRUG ERUPTIONS; DRUG HYPERSENSITIVITY; FEMALE; HISTAMINE RELEASE; HUMANS; INTERFERON TYPE II; MALE; MIDDLE AGED; SKIN DISEASES;

EID: 21044448508     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1080/10446670410001722230     Document Type: Article

References (32)

1. Adkinson NK. 2003. Drug allergy. In: Adkinson NK, Yunginger JW, Busse WW, Bochner BS, Holgate ST, Simmons ER, editors. Middleton's allergy: Principles and practice. 6th ed. Mosby. p 1679-1694.
2. Armstrong B, Dinan B, Jick H. 1976. Fatal drug reactions in patients admitted to surgical services. Am J Surg 132:643-645.
3. Boston Collaborative Drug Surveillance Program 1973. Drug-induced anaphylaxis: A cooperative study. JAMA 224:613-615.
4. Brenner S, Bialy-Golan A, Ruocco V. 1998. Drug-induced pemphigus. Clin Dermatol 16:393-397.
5. Cohen CJ, Denkberg G, Schiffenbauer YS, Segal D, Trubniykov E, Berke G, Reiter Y. 2003. Simultaneous monitoring of binding to and activation of tumor-specific T lymphocytes by peptide-MHC. J Immunol Methods 9346:1-14.
6. DeSwarte RD. 1993. Drug.allergy. In: Patterson R, Grammer LC, Greenberg PA, Zeiss CR, editors. Allergic diseases: Diagnosis and management. 4th ed. Philadelphia, PA: JB Lippincott. p 395-551.
7. Deutsch M, Weinreb A. 1994. Apparatus of high precision repetitive sequential optical measurement of living cells. Cytometry 16:214-226.
8. Eisenthal A, Marder O, Dotan D, Baron S, Lifschitz-Mercer B, Chaitchik S, Tirosh R, Weinreb A, Deutsch M. 1996. Decrease of intracellular fluorescein fluorescence polarization (IFFP) in human peripheral blood lymphocytes undergoing stimulation with phytohaemagglutinin (PHA), concanavalin A (ConA), pokeweed mitogen (PWM) and anti-CD3 antibody. Biol Cell 86:145-150.
9. Gimenez-Camarasa JM, Garcia-Calderon P, De Moragas JM. 1975. Lymphocyte transformtion test in fixed drug eruption. N Engl J Med 292:819-821.
10. Goldberg I, Gilburd B, Shovman O, Brenner S. 2004. Clinical and laboratory assays in the diagnosis of cutaneous adverse drug reactions. Isr Med Assoc J 6:50-51.
11. Grunwald MH, Halevy S, Livni E. 1989. Allergic vasculitis induced by hydrochlorthiazide: Confirmation by mast cell degranulation test. Isr J Med Sci 25:572-574.
12. Halevy S. 1998. In-vitro tests for adverse drug reactions based on cytoldne release. In: Kauppinen K, Alanko K, Hannuksela M, Maibach H, editors. In-vitro tests for adverse drug reactions based on cytokine release. Boca Raton, FL: CRC Press LLC. p 119-131.
13. Halevy S, Feuerman EJ. 1984. (Heb) drug induced eruptions which mimic skin diseases. Fam Physician 12:267.
14. Halevy S, Grunwald MH, Sandbank M, et al. 1991. Macrophage migration inhibition factor (MIF) as a diagnostic aid in drug eruptions. Harefuah 121:147-149.
15. Halevy S, Cohen AD, Grossman N. 2001. In vitro interferon gamma release in diagnosis of cutaneous adverse drug reactions. Harefuah 140:121-124.
16. Kaplan MR, Trubniykov E, Berke G. 1997. Fluorescence depolarization as an early measure of lymphocyte stimulation. J Immunol Methods 201:15-24.
17. Lazarou J, Pomeranz BH, Corey PN. 1998. Incidence of adverse drug reactions in hospitalized patients. A meta-analysis of prospective studies. JAMA 279:1200-1205.
18. Merimsky O, Deutsch M, Tirosh R, Wohl I, Weinreb A, Chaitchik S. 1996. Detection of colon cancer by monitoring the intracellular fluorescein fluorescence polarization changes in lymphocytes. Cancer Detection and Prevention 20:300-307.
19. Porter J, Jick H. 1977. Drug-related deaths among medical inpatients. JAMA 237:879-881.
20. Rahmani H, Deutsch M, Ron I, Gerbat S, Tirosh R, Weinreb A, Chaitchik S, Lalchuk S. 1996. Adaptation of the Cellscan technique for the SCM test in breast cancer. Eur J Cancer 32A:1758-1765.
21. Ron IG, Detusch M, Tirosh R, Weinreb A, Eisenthal A, Chaitchik S. 1995. Fluorescence polarization changes in the lymphocytic cytoplasm in the various stages of brest cancer. Eur J Cancer 6:917-920.
22. Sachs B, Ederman S, Al-Masaoudi T, Merk HF. 2001. In vitro drug allergy detection system incorporating human liver microsomes in chlorazepate-induced skin rash: Drug-specific proliferation associated with interleukin-5 secretion. Br J Dermatol 144:316-320.
23. Schiffenbauer YS, Trubniykov E, Zacharia BT, Gerbat S, Rehavi Z, Berke G, Chaitchik S. 2002. Tumor sensitivity to anti-cancer drugs predicted by changes in fluorescence intensity and polarization in vitro. Anticancer Res 22:2663-2670.
24. Shefferd GM. 2003. Hypersensitivity reactions to drugs: Evaluation and management. Mt Sinai J Med 70:113-125.
25. Shoenfeld Y. 1982. "Leukopenia: Idiopathic or drug-induced"-how to differentiate? N Engl J Med 307:251.
26. Shoenfeld Y, Livni E, Shaklai M, Pinkhas J. 1980. Sensitization to ibuprofen in systemic lupus erythematosus. JAMA 244:547-548.
27. Watson B, Rhodes EL, Rosling AE. 1978. The release of beta glucuronidase from the white cells of patients with drug rashes when incubated in autologous plasma, with and without the addition of the causal drug. Br J Dermatol 99:183-190.
28. Wide L, Juhlin L. 1971. Detection of penicillin allergy of the immediate type by radioimmunoassay of reagins (IgE) to penicilloyl conjugates. Clin Allergy 1:171.
29. Zurgil N, Deutsch M, Tirosh R, Brodie C. 1996. Indication that intracellular fluorescence polarization of T lymphocytes is cell cycle dependent. Cell Struct Funct 21:271-276.
30. Zurgil N, Gerbat S, Langevitzh P, Tishler M, Ehrenfeld M, Shoenfeld Y. 1997. Intracellular fluorescence polarization measurements by the cellscan system: Detraction of cellular activity in autoimmune disorders. Isr J Med Sci 33:273-279.
31. Zurgil N, Gerbat S, Langevits P, Tishler M, Ehrenfeld M, Kaufman M, Deutsch M, Shoenfeld Y. 1999. Detection of cellular activity in autoimmune disorders by the cellscan system. In: Shoenfeld Y, editor. The decade of autoimmunity. V. Elsevier Science, B.V. p 295-304.
32. Zurgil N, Levy M, Deutsch M, Gilburd B, George J, Haratz D, Kaufman M, Shoenfeld Y. 1999. Reactivity of peripheral blood lymphocytes to oxidized low-density lipoprotein: A novel system to estimate atherosclerosis employing the cellscan. Clin Cardiol 22:526-532.