Synthesis and structure-activity relationships of (R)-1-alkyl-3-[2-(2- amino)phenethyl]-5-(2-fluorophenyl)-6-methyluracils as human GnRH receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 9, 2004, Pages 2269-2274

  Rowbottom, Martin W ^a   Tucci, Fabio C ^a   Zhu, Yun Fei ^a   Guo, Zhiqiang ^a   Gross, Timothy D ^a   Reinhart, Greg J ^a   Xie, Qui ^a   Struthers, R Scott ^a   Saunders, John ^a   Chen, Chen ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYL DERIVATIVE; GONADORELIN RECEPTOR ANTAGONIST; HORMONE INHIBITOR; THYMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

HUMANS; RECEPTORS, LHRH; STRUCTURE-ACTIVITY RELATIONSHIP; URACIL;

EID: 11144358660     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.02.004     Document Type: Article

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