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Volumn 7, Issue 4, 2004, Pages 233-241

Glucocorticoid receptor antagonists: New tools to investigate disorders characterized by cortisol hypersecretion

Author keywords

Antiglucocorticoid; Depression; HPA axis; Hypercortisolemia; Mineralocorticoid receptor; Progesterone receptor

Indexed keywords

11BETA (1,3 BENZODIOXOL 5 YL) 17BETA HYDROXY 17ALPHA (1 PROPYNYL)ESTRA 4,9 DIEN 3 ONE; ALDOSTERONE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; HYDROCORTISONE; MIFEPRISTONE; MINERALOCORTICOID RECEPTOR; ORG 21863; ORG 34850; ORG 36174; ORG 36293; ORG 36294; ORG 36410; ORG 36411; ORG 36446; PLACEBO; PROGESTERONE RECEPTOR; UNCLASSIFIED DRUG;

EID: 20944443639     PISSN: 10253890     EISSN: None     Source Type: Journal    
DOI: 10.1080/10253890400019672     Document Type: Short Survey
Times cited : (38)

References (102)
  • 1
    • 0029897502 scopus 로고    scopus 로고
    • Enhancement of the prolactin response to d-fenfluramine in drug-naïve schizophrenic patients
    • Abel, K.M., O'Keane, V. and Murray, R.M. (1996) Enhancement of the prolactin response to d-fenfluramine in drug-naïve schizophrenic patients, Br. J. Psychiat. 168, 57-60.
    • (1996) Br. J. Psychiat. , vol.168 , pp. 57-60
    • Abel, K.M.1    O'Keane, V.2    Murray, R.M.3
  • 2
    • 0016824330 scopus 로고
    • Effect of cortexolone on the feedback action of dexamethasone
    • Acs, Z. and Start, E. (1975) Effect of cortexolone on the feedback action of dexamethasone, Experientia 31, 1365-1366.
    • (1975) Experientia , vol.31 , pp. 1365-1366
    • Acs, Z.1    Start, E.2
  • 4
    • 0038320627 scopus 로고    scopus 로고
    • Glucocorticoids: New mechanisms and future agents
    • Adcock, I.M. (2003) Glucocorticoids: new mechanisms and future agents, Curr. Allergy Asthma Rep. 3, 249-257.
    • (2003) Curr. Allergy Asthma Rep. , vol.3 , pp. 249-257
    • Adcock, I.M.1
  • 5
    • 0011753679 scopus 로고
    • Hormone-hormone antagonism in glucocorticoid action in vivo
    • Elsevier, North Holland, Amsterdam
    • Agarwal, M.K., Sekiya, S. and Lazar, G. (1979a) Hormone-hormone antagonism in glucocorticoid action in vivo, Antihormones (Elsevier, North Holland, Amsterdam), pp 51-73.
    • (1979) Antihormones , pp. 51-73
    • Agarwal, M.K.1    Sekiya, S.2    Lazar, G.3
  • 6
    • 0018601215 scopus 로고
    • Search for anti-glucocorticoid activity in rat liver in vivo
    • Agarwal, M.K., Sekiya, S. and Lazar, G. (1979b) Search for anti-glucocorticoid activity in rat liver in vivo, Res. Exp. Med. 176, 181-192.
    • (1979) Res. Exp. Med. , vol.176 , pp. 181-192
    • Agarwal, M.K.1    Sekiya, S.2    Lazar, G.3
  • 7
    • 0026079736 scopus 로고
    • Overexpression and characterization of the human mineralocorticoid receptor
    • Alnemri, E.S., Maksymowych, A.B., Robertson, N.M. and Litwack, G. (1991) Overexpression and characterization of the human mineralocorticoid receptor, J. Biol. Chem. 266, 18072-18081.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18072-18081
    • Alnemri, E.S.1    Maksymowych, A.B.2    Robertson, N.M.3    Litwack, G.4
  • 10
    • 0023221667 scopus 로고
    • Cloning of human mineralocorticoid receptor complementary DNA, structural and functional kinship with the glucocorticoid receptor
    • Arriza, J.L., Weinberger, C., Cerelli, G., Glaser, T.M., Handelin, B.L., Housman, D.E. and Evans, R.M. (1987) Cloning of human mineralocorticoid receptor complementary DNA, structural and functional kinship with the glucocorticoid receptor, Science 237, 268-275.
    • (1987) Science , vol.237 , pp. 268-275
    • Arriza, J.L.1    Weinberger, C.2    Cerelli, G.3    Glaser, T.M.4    Handelin, B.L.5    Housman, D.E.6    Evans, R.M.7
  • 11
    • 0024109575 scopus 로고
    • The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response
    • Arriza, J.L., Simerly, R.B., Swanson, L.W. and Evans, R.M. (1988) The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response, Neuron 1, 887-900.
    • (1988) Neuron , vol.1 , pp. 887-900
    • Arriza, J.L.1    Simerly, R.B.2    Swanson, L.W.3    Evans, R.M.4
  • 15
    • 0022442657 scopus 로고
    • Pituitary-adrenal response to the antiglucocorticoid action of RU486 in Cushing's syndrome
    • Bertagna, X., Bertagna, C., Laudat, M.H., Husson, J.M. and Girard, F. (1986) Pituitary-adrenal response to the antiglucocorticoid action of RU486 in Cushing's syndrome, J. Clin. Endocrinol. Metab. 63, 639-642.
    • (1986) J. Clin. Endocrinol. Metab. , vol.63 , pp. 639-642
    • Bertagna, X.1    Bertagna, C.2    Laudat, M.H.3    Husson, J.M.4    Girard, F.5
  • 16
    • 0025787868 scopus 로고
    • Characterization of human mineralocorticoid receptor expressed in the baculovirus system
    • Binart, N., Lombes, M., Rafestin-Obelin, M.E. and Baulieu, E.E. (1991) Characterization of human mineralocorticoid receptor expressed in the baculovirus system, Proc. Natl Acad. Sci. USA 88, 10681-10685.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10681-10685
    • Binart, N.1    Lombes, M.2    Rafestin-Obelin, M.E.3    Baulieu, E.E.4
  • 18
    • 0036877736 scopus 로고    scopus 로고
    • Corticosteroid-induced hypersensitivity reactions
    • Butani, L. (2002) Corticosteroid-induced hypersensitivity reactions, Ann. Allergy Asthma Immunol. 89, 439-446.
    • (2002) Ann. Allergy Asthma Immunol. , vol.89 , pp. 439-446
    • Butani, L.1
  • 19
    • 0033663552 scopus 로고    scopus 로고
    • Ocular complications of topical, peri-ocular, and systemic corticosteroids
    • Carnahan, M.C. and Goldstein, D.A. (2000) Ocular complications of topical, peri-ocular, and systemic corticosteroids, Curr. Opin. Ophthalmol. 11, 478-483.
    • (2000) Curr. Opin. Ophthalmol. , vol.11 , pp. 478-483
    • Carnahan, M.C.1    Goldstein, D.A.2
  • 22
    • 1542573352 scopus 로고    scopus 로고
    • The pursuit of differentiated ligands for the glucocorticoid receptor
    • Coghlan, M.J., Elmore, S.W., Kym, P.R. and Kort, M.E. (2003) The pursuit of differentiated ligands for the glucocorticoid receptor, Curr. Top. Med. Chem. 3, 1617-1635.
    • (2003) Curr. Top. Med. Chem. , vol.3 , pp. 1617-1635
    • Coghlan, M.J.1    Elmore, S.W.2    Kym, P.R.3    Kort, M.E.4
  • 23
    • 2542490348 scopus 로고    scopus 로고
    • Minireview: Glucocorticoids-food intake, abdominal obesity, and wealthy nations in 2004
    • Dallman, M.F., la Fleur, S.E., Pecoraro, N.C., Gomez, F., Houshyar, H. and Akana, S.F. (2004) Minireview: glucocorticoids-food intake, abdominal obesity, and wealthy nations in 2004, Endocrinology 145, 2633-2638.
    • (2004) Endocrinology , vol.145 , pp. 2633-2638
    • Dallman, M.F.1    La Fleur, S.E.2    Pecoraro, N.C.3    Gomez, F.4    Houshyar, H.5    Akana, S.F.6
  • 26
    • 0029937367 scopus 로고    scopus 로고
    • Noradrenergic and serotonergic abnormalities in depression, stress-induced dysfunction?
    • Dinan, T.G. (1996) Noradrenergic and serotonergic abnormalities in depression, stress-induced dysfunction?, J. Clin. Psychiatry 57, 14-18.
    • (1996) J. Clin. Psychiatry , vol.57 , pp. 14-18
    • Dinan, T.G.1
  • 27
    • 0002426639 scopus 로고
    • Structural characteristics of antagonists for gluco- and mineralocorticoids
    • Agarwal, M.K., (ed.), (Walter de Gruyter, Berlin, New York)
    • Duax, W.L. and Griffin, J.F. (1984) Structural characteristics of antagonists for gluco- and mineralocorticoids, In: Agarwal, M.K., (ed.), Adrenal Steroid Antagonism (Walter de Gruyter, Berlin, New York), pp 15-41.
    • (1984) Adrenal Steroid Antagonism , pp. 15-41
    • Duax, W.L.1    Griffin, J.F.2
  • 28
    • 0011788923 scopus 로고
    • Steroid antagonists, molecular conformation, receptor binding and activity
    • Agarwal, M.K. (ed.), (Walter de Gruyter, Berlin)
    • Duax, W.L., Griffin, J.F., Rohrer, D.C. and Weeks, C.H. (1982) Steroid antagonists, molecular conformation, receptor binding and activity, In: Agarwal, M.K. (ed.), Hormone Antagonists (Walter de Gruyter, Berlin), pp 3-24.
    • (1982) Hormone Antagonists , pp. 3-24
    • Duax, W.L.1    Griffin, J.F.2    Rohrer, D.C.3    Weeks, C.H.4
  • 29
    • 0024609377 scopus 로고
    • A molecular framework for the action of glucocorticoid hormones in the nervous system
    • Evans, R.M. and Arriza, J.L. (1989) A molecular framework for the action of glucocorticoid hormones in the nervous system, Neuron 2, 1105-1112.
    • (1989) Neuron , vol.2 , pp. 1105-1112
    • Evans, R.M.1    Arriza, J.L.2
  • 30
    • 3142621133 scopus 로고    scopus 로고
    • Glucocorticoid-mediated mineralocorticoid receptor activation and hypertension
    • Frey, F.J., Odermatt, A. and Frey, B.M. (2004) Glucocorticoid-mediated mineralocorticoid receptor activation and hypertension, Curr. Opin. Nephrol. Hypertens. 13, 451-458.
    • (2004) Curr. Opin. Nephrol. Hypertens. , vol.13 , pp. 451-458
    • Frey, F.J.1    Odermatt, A.2    Frey, B.M.3
  • 31
    • 0030886442 scopus 로고    scopus 로고
    • 11,21-Bisphenyl-19-norpregnane derivatives are selective antiglucocorticoids
    • Gebhard, R., Van der Voort, H., Schuts, W. and Schoonen, W. (1997) 11,21-Bisphenyl-19-norpregnane derivatives are selective antiglucocorticoids, Bioorg. Med. Chem. Lett. 7, 2229-2234.
    • (1997) Bioorg. Med. Chem. Lett. , vol.7 , pp. 2229-2234
    • Gebhard, R.1    Van Der Voort, H.2    Schuts, W.3    Schoonen, W.4
  • 33
    • 0022453518 scopus 로고
    • Functional domains of the human glucocorticoid receptor
    • Giguere, V., Hollenberg, S.M., Rosenfeld, M.G. and Evans, R.M. (1986) Functional domains of the human glucocorticoid receptor, Cell 46, 645-652.
    • (1986) Cell , vol.46 , pp. 645-652
    • Giguere, V.1    Hollenberg, S.M.2    Rosenfeld, M.G.3    Evans, R.M.4
  • 34
    • 0027415530 scopus 로고
    • Dose-response relationships of RU486
    • Heikinheimo, O. and Kekkonen, R. (1993) Dose-response relationships of RU486, Ann. Med. 25, 71-76.
    • (1993) Ann. Med. , vol.25 , pp. 71-76
    • Heikinheimo, O.1    Kekkonen, R.2
  • 35
    • 0023250459 scopus 로고
    • Metabolism and serum binding of RU486 in women after various single doses
    • Heikinheimo, O., Lahteenmaki, P. and Koivunen, E. (1987) Metabolism and serum binding of RU486 in women after various single doses, Hum. Reprod. 2, 379-385.
    • (1987) Hum. Reprod. , vol.2 , pp. 379-385
    • Heikinheimo, O.1    Lahteenmaki, P.2    Koivunen, E.3
  • 36
    • 0011729053 scopus 로고
    • The control of glycogen metabolism in liver
    • Hers, H.G. and Stalmans, W. (1970) The control of glycogen metabolism in liver, FEBS Lett. 12, 73-82.
    • (1970) FEBS Lett. , vol.12 , pp. 73-82
    • Hers, H.G.1    Stalmans, W.2
  • 37
    • 0023794190 scopus 로고
    • Multiple and cooperative transactivation domains of the human glucocorticoid receptor
    • Hollenberg, S.M. and Evans, R.M. (1988) Multiple and cooperative transactivation domains of the human glucocorticoid receptor, Cell 55, 899-906.
    • (1988) Cell , vol.55 , pp. 899-906
    • Hollenberg, S.M.1    Evans, R.M.2
  • 38
    • 0035153486 scopus 로고    scopus 로고
    • Stress, hypercortisolism and corticosteroid receptors in depression: Implications for therapy
    • Holsboer, F. (2001) Stress, hypercortisolism and corticosteroid receptors in depression: implications for therapy, J. Affect Disord. 62, 77-91.
    • (2001) J. Affect Disord. , vol.62 , pp. 77-91
    • Holsboer, F.1
  • 39
    • 0029926722 scopus 로고    scopus 로고
    • Antidepressants and hypothalamic-pituitary-adrenocortical regulation
    • Holsboer, F. and Barden, N. (1996) Antidepressants and hypothalamic-pituitary-adrenocortical regulation, Endocr. Rev. 17, 187-205.
    • (1996) Endocr. Rev. , vol.17 , pp. 187-205
    • Holsboer, F.1    Barden, N.2
  • 40
    • 0023272480 scopus 로고
    • The diurnal variation and response to dexamethasone suppression test of saliva cortisol level in autistic children
    • Hoshino, Y., Yokoyama, F., Watanabe, M., Murata, S., Kaneko, M. and Kumashiro, H. (1987) The diurnal variation and response to dexamethasone suppression test of saliva cortisol level in autistic children, Jap. J. Psychiatr. Neurol. 41, 227-235.
    • (1987) Jap. J. Psychiatr. Neurol. , vol.41 , pp. 227-235
    • Hoshino, Y.1    Yokoyama, F.2    Watanabe, M.3    Murata, S.4    Kaneko, M.5    Kumashiro, H.6
  • 41
    • 0017035887 scopus 로고
    • Structure-activity relationship and the mode of action of corticosteroid feedback on the secretion of corticotrophin-releasing factor (corticoliberin)
    • Jones, M.T. and Hillhouse, E.W. (1976) Structure-activity relationship and the mode of action of corticosteroid feedback on the secretion of corticotrophin-releasing factor (corticoliberin), J. Steroid Biochem. 7, 1189-1202.
    • (1976) J. Steroid Biochem. , vol.7 , pp. 1189-1202
    • Jones, M.T.1    Hillhouse, E.W.2
  • 45
    • 0027290967 scopus 로고
    • Effects of the glucocorticoid antagonist RU486 on pituitary-adrenal function in patients with anorexia nervosa and healthy volunteers, enhancement of plasma ACTH and cortisol secretion in underweight patients
    • Kling, M.A., Demitrack, M.A., Whitfield, H.J., Kalogeras, K.T., Listwak, S.J., DeBellis, M.D., Chrousos, G.P., Gold, P.W. and Brandt, H.A. (1993) Effects of the glucocorticoid antagonist RU486 on pituitary-adrenal function in patients with anorexia nervosa and healthy volunteers, enhancement of plasma ACTH and cortisol secretion in underweight patients, Neuroendocrinology 57, 1082-1091.
    • (1993) Neuroendocrinology , vol.57 , pp. 1082-1091
    • Kling, M.A.1    Demitrack, M.A.2    Whitfield, H.J.3    Kalogeras, K.T.4    Listwak, S.J.5    Debellis, M.D.6    Chrousos, G.P.7    Gold, P.W.8    Brandt, H.A.9
  • 46
    • 0027096711 scopus 로고
    • Corticosteroids, stress and aging
    • de Kloet, E.R. (1992) Corticosteroids, stress and aging, Ann. NY Acad. Sci. 663, 357-371.
    • (1992) Ann. NY Acad. Sci. , vol.663 , pp. 357-371
    • Kloet, E.R.1
  • 49
    • 0033054115 scopus 로고    scopus 로고
    • The structure of the nuclear hormone receptors
    • Kumar, R. and Thompson, E.B. (1999) The structure of the nuclear hormone receptors, Steroids 64, 310-319.
    • (1999) Steroids , vol.64 , pp. 310-319
    • Kumar, R.1    Thompson, E.B.2
  • 51
    • 0026524715 scopus 로고
    • A model for the determination of the 3D-spatial distribution of the functions of the hormone-binding domain of receptors that bind 3-keto-4-ene steroids
    • Lemesle-Varloot, L., Ojasoo, T., Mornon, J.P. and Raynaud, J.P. (1992) A model for the determination of the 3D-spatial distribution of the functions of the hormone-binding domain of receptors that bind 3-keto-4-ene steroids, J. Steroid Biochem. Mol. Biol. 41, 369-388.
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.41 , pp. 369-388
    • Lemesle-Varloot, L.1    Ojasoo, T.2    Mornon, J.P.3    Raynaud, J.P.4
  • 55
    • 0030670753 scopus 로고    scopus 로고
    • Beta-endorphin, adrenocorticotropic hormone and cortisol secretion in abstinent alcoholics
    • Marchesi, C., Chiodera, P., Ampollini, P., Volpi, R. and Coiro, V. (1997) Beta-endorphin, adrenocorticotropic hormone and cortisol secretion in abstinent alcoholics, Psychiatry Res. 72, 187-194.
    • (1997) Psychiatry Res. , vol.72 , pp. 187-194
    • Marchesi, C.1    Chiodera, P.2    Ampollini, P.3    Volpi, R.4    Coiro, V.5
  • 60
    • 0011788926 scopus 로고
    • Antiglucocorticoids, differential antagonism of in vivo responses to dexamethasone
    • Agarwal, M.K., (ed.), (Walter de Gruyter, Berlin)
    • Naylor, P.H. and Rosen, F. (1982) Antiglucocorticoids, differential antagonism of in vivo responses to dexamethasone, In: Agarwal, M.K., (ed.), Hormone antagonists (Walter de Gruyter, Berlin), pp 365-380.
    • (1982) Hormone Antagonists , pp. 365-380
    • Naylor, P.H.1    Rosen, F.2
  • 61
    • 0018820491 scopus 로고
    • Antiglucocorticoids, in vivo assay and evaluation of cortexolone, progesterone and 6-β-bromoprogesterone
    • Naylor, P.H., Gilani, S.S., Milholland, R.J. and Rosen, F. (1980) Antiglucocorticoids, in vivo assay and evaluation of cortexolone, progesterone and 6-β-bromoprogesterone, Endocrinology 107, 117-121.
    • (1980) Endocrinology , vol.107 , pp. 117-121
    • Naylor, P.H.1    Gilani, S.S.2    Milholland, R.J.3    Rosen, F.4
  • 62
    • 0021610642 scopus 로고
    • New steroids with antiprogestational and antiglucocorticoid activity
    • Neef, G., Beier, S., Elger, W., Henderson, D. and Wiechert, R. (1984) New steroids with antiprogestational and antiglucocorticoid activity, Steroids 44, 349-372.
    • (1984) Steroids , vol.44 , pp. 349-372
    • Neef, G.1    Beier, S.2    Elger, W.3    Henderson, D.4    Wiechert, R.5
  • 63
    • 0029876653 scopus 로고    scopus 로고
    • Elevated serum prolactin or elevated prolactin/cortisol ratio are associated with autoimmune processes in systemic lupus erythematosus and other connective tissue diseases
    • Neidhart, M. (1996) Elevated serum prolactin or elevated prolactin / cortisol ratio are associated with autoimmune processes in systemic lupus erythematosus and other connective tissue diseases, J. Rheumatol. 23, 476-481.
    • (1996) J. Rheumatol. , vol.23 , pp. 476-481
    • Neidhart, M.1
  • 64
    • 1842288547 scopus 로고    scopus 로고
    • DST studies in psychotic depression, a meta-analysis
    • Nelson, J.C. and Davis, J.M. (1997) DST studies in psychotic depression, a meta-analysis, Am. J. Psychiatry 154, 1497-1503.
    • (1997) Am. J. Psychiatry , vol.154 , pp. 1497-1503
    • Nelson, J.C.1    Davis, J.M.2
  • 65
    • 0021970821 scopus 로고
    • Successful treatment of Cushing's syndrome with the glucocorticoid antagonist RU486
    • Nieman, L.K., Chrousos, O.P. and Nisula, B.C. (1985) Successful treatment of Cushing's syndrome with the glucocorticoid antagonist RU486, J. Clin. Endocrinol. Metab. 61, 536-540.
    • (1985) J. Clin. Endocrinol. Metab. , vol.61 , pp. 536-540
    • Nieman, L.K.1    Chrousos, O.P.2    Nisula, B.C.3
  • 67
    • 0017225139 scopus 로고
    • Effects of glucocorticoids on carbohydrate metabolism
    • Olefsky, J. and Kimmerling, G. (1976) Effects of glucocorticoids on carbohydrate metabolism, Am. J. Med. Sci. 271, 202-210.
    • (1976) Am. J. Med. Sci. , vol.271 , pp. 202-210
    • Olefsky, J.1    Kimmerling, G.2
  • 68
    • 0021659714 scopus 로고
    • Synthesis of ent-17-(prop-1-ynyl-17β-hydroxy-11β-(4-N,N- dimethylamino)-phenyl)-4,9-estradien-3-one, the antipode of RU38486
    • Ottow, E., Beier, S., Elger, W., Henderson, D.A., Neef, G. and Wiechert, R. (1984) Synthesis of ent-17-(prop-1-ynyl-17β-hydroxy-11β-(4-N,N- dimethylamino)-phenyl)-4,9-estradien-3-one, the antipode of RU38486, Steroids 44, 519-530.
    • (1984) Steroids , vol.44 , pp. 519-530
    • Ottow, E.1    Beier, S.2    Elger, W.3    Henderson, D.A.4    Neef, G.5    Wiechert, R.6
  • 70
    • 0037222783 scopus 로고    scopus 로고
    • Neuroendocrine aspects of hypercortisolism in major depression
    • Parker, K.J., Schatzberg, A.F. and Lyons, D.M. (2003) Neuroendocrine aspects of hypercortisolism in major depression, Horm. Behav. 43, 60-66.
    • (2003) Horm. Behav. , vol.43 , pp. 60-66
    • Parker, K.J.1    Schatzberg, A.F.2    Lyons, D.M.3
  • 71
    • 0027740307 scopus 로고
    • Possible use of glucocorticoid receptor antagonists in the treatment of major depression, preliminary results using RU486
    • Pearson Murphy, B.E., Filipini, D. and Ghadirian, A.M. (1993) Possible use of glucocorticoid receptor antagonists in the treatment of major depression, preliminary results using RU486, J. Psychiatr. Neurosci. 18, 209-213.
    • (1993) J. Psychiatr. Neurosci. , vol.18 , pp. 209-213
    • Pearson Murphy, B.E.1    Filipini, D.2    Ghadirian, A.M.3
  • 72
    • 0027971206 scopus 로고
    • Involvement of corticosteroids in the processing of stressful life-events. A possible implication for the development of depression
    • Peeters, B.W. and Broekkamp, C.L. (1994) Involvement of corticosteroids in the processing of stressful life-events. A possible implication for the development of depression, J. Steroid Biochem. Mol. Biol. 49, 417-427.
    • (1994) J. Steroid Biochem. Mol. Biol. , vol.49 , pp. 417-427
    • Peeters, B.W.1    Broekkamp, C.L.2
  • 73
    • 0037458439 scopus 로고    scopus 로고
    • Molecular mechanisms of corticosteroid actions in chronic inflammatory airway diseases
    • Pelaia, G., Vatrella, A., Cuda, G., Maselli, R. and Marsico, S.A. (2003) Molecular mechanisms of corticosteroid actions in chronic inflammatory airway diseases, Life Sci. 72, 1549-1561.
    • (2003) Life Sci. , vol.72 , pp. 1549-1561
    • Pelaia, G.1    Vatrella, A.2    Cuda, G.3    Maselli, R.4    Marsico, S.A.5
  • 75
    • 0023946880 scopus 로고
    • A model of antiglucocorticoid action for designing a potent glucocorticoid antagonist
    • Pons, M. and Gagne, D. (1988) A model of antiglucocorticoid action for designing a potent glucocorticoid antagonist, J. Steroid Biochem. 29, 239-247.
    • (1988) J. Steroid Biochem. , vol.29 , pp. 239-247
    • Pons, M.1    Gagne, D.2
  • 76
    • 0017518663 scopus 로고
    • Relative binding affinity of androstane and C-19-norandrostane-steroids for the estradiol-receptor in human myometrial and mammary cancer tissue
    • Poortman, J., Vroegindewey-Jie, D., Thyssen, J.H. and Schwarz, F. (1977) Relative binding affinity of androstane and C-19-norandrostane-steroids for the estradiol-receptor in human myometrial and mammary cancer tissue, Mol. Cell. Endocrinol. 8, 27-34.
    • (1977) Mol. Cell. Endocrinol. , vol.8 , pp. 27-34
    • Poortman, J.1    Vroegindewey-Jie, D.2    Thyssen, J.H.3    Schwarz, F.4
  • 77
    • 0022383620 scopus 로고
    • Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation
    • Reul, J.M. and de Kloet, E.R. (1985) Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation, Endocrinology 117, 2505-2511.
    • (1985) Endocrinology , vol.117 , pp. 2505-2511
    • Reul, J.M.1    De Kloet, E.R.2
  • 78
    • 0026788578 scopus 로고
    • Urinary cortisol circadian rhythm in a group of high-functioning children with autism
    • Richdale, A.L. and Prior, M.R. (1992) Urinary cortisol circadian rhythm in a group of high-functioning children with autism, J. Autism Dev. Disord. 22, 433-447.
    • (1992) J. Autism Dev. Disord. , vol.22 , pp. 433-447
    • Richdale, A.L.1    Prior, M.R.2
  • 80
    • 0031964780 scopus 로고    scopus 로고
    • Increased urinary-free cortisol outputs in diabetic patients
    • Roy, M.S., Roy, A. and Brown, S. (1998) Increased urinary-free cortisol outputs in diabetic patients, J. Diabetes Complications 12, 24-27.
    • (1998) J. Diabetes Complications , vol.12 , pp. 24-27
    • Roy, M.S.1    Roy, A.2    Brown, S.3
  • 81
    • 0027175669 scopus 로고
    • Trans-activation and synergistic properties of the mineralocorticoid receptor, relationship to the glucocorticoid receptor
    • Rupprecht, R., Arriza, J.L., Spengler, D., Reul, J.M.H.M., Evans, R.M., Holsboer, F. and Damm, K. (1993) Trans-activation and synergistic properties of the mineralocorticoid receptor, relationship to the glucocorticoid receptor, Mol. Endocrinol. 7, 597-603.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 597-603
    • Rupprecht, R.1    Arriza, J.L.2    Spengler, D.3    Reul, J.M.H.M.4    Evans, R.M.5    Holsboer, F.6    Damm, K.7
  • 83
    • 0038653148 scopus 로고    scopus 로고
    • DHEA, a selective glucocorticoid receptor antagonist: Its role in immune system regulation and metabolism
    • Sacco, M., Valenti, G., Corvi Mora, P., Wu, F.C. and Ray, D.W. (2002) DHEA, a selective glucocorticoid receptor antagonist: its role in immune system regulation and metabolism, J. Endocrinol. Investig. 25, 81-82.
    • (2002) J. Endocrinol. Investig. , vol.25 , pp. 81-82
    • Sacco, M.1    Valenti, G.2    Corvi Mora, P.3    Wu, F.C.4    Ray, D.W.5
  • 85
    • 0033800486 scopus 로고    scopus 로고
    • Glucocorticoids and hippocampal atrophy in neuropsychiatrie disorders
    • Sapolsky, R.M. (2000) Glucocorticoids and hippocampal atrophy in neuropsychiatrie disorders, Arch. Gen. Psychiatry 57, 925-935.
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 925-935
    • Sapolsky, R.M.1
  • 86
    • 0037051129 scopus 로고    scopus 로고
    • Mifepristone: Bioavailability, pharmacokinetics and use-effectiveness
    • Sarkar, N.N. (2002) Mifepristone: bioavailability, pharmacokinetics and use-effectiveness, Eur. J. Obstet. Gynaecol. Reprod. Biol. 101, 113-120.
    • (2002) Eur. J. Obstet. Gynaecol. Reprod. Biol. , vol.101 , pp. 113-120
    • Sarkar, N.N.1
  • 87
    • 0037277047 scopus 로고    scopus 로고
    • New approaches to managing psychotic depression
    • Schatzberg, A.F. (2003) New approaches to managing psychotic depression, J. Clin. Psychiatry 64(S1), 19-23.
    • (2003) J. Clin. Psychiatry , vol.64 , Issue.S1 , pp. 19-23
    • Schatzberg, A.F.1
  • 88
    • 0023157488 scopus 로고
    • Analysis of the glucocorticoid antagonist action of dexamethasone 21-mesylate in HeLa S3 cells
    • Scheible, P.P., DeLorenzo, T.M. and Cidlowski, J.A. (1987) Analysis of the glucocorticoid antagonist action of dexamethasone 21-mesylate in HeLa S3 cells, J. Steroid Biochem. 26, 181-187.
    • (1987) J. Steroid Biochem. , vol.26 , pp. 181-187
    • Scheible, P.P.1    Delorenzo, T.M.2    Cidlowski, J.A.3
  • 89
    • 17844372924 scopus 로고    scopus 로고
    • Org 34517, a selective glucocorticoid receptor antagonist with strong antidepressant activity in man: First clinical results
    • Doorwerth
    • Sennef, C., Hoyberg, O.J., Wik, G., Mehtonen, O.P. and Peeters, B.W.M.M. (2002) Org 34517, a selective glucocorticoid receptor antagonist with strong antidepressant activity in man: first clinical results. First Dutch Endo-Neuro-Psycho Meeting, Doorwerth.
    • (2002) First Dutch Endo-Neuro-Psycho Meeting
    • Sennef, C.1    Hoyberg, O.J.2    Wik, G.3    Mehtonen, O.P.4    Peeters, B.W.M.M.5
  • 90
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau, A.K., Barstad, D., Loria, P.M., Cheng, L., Kushner, P.J., Agard, D.A. and Greene, G.L. (1998) The structural basis of estrogen/coactivator recognition and the antagonism of this interaction by tamoxifen, Cell 95, 927-937.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6    Greene, G.L.7
  • 91
    • 0022551184 scopus 로고
    • Affinity-labeling steroids as biologically active probes of antiglucocorticoid hormone action
    • Simons, S.S. and Miller, P.A. (1986) Affinity-labeling steroids as biologically active probes of antiglucocorticoid hormone action, J. Steroid Biochem. 24, 25-32.
    • (1986) J. Steroid Biochem. , vol.24 , pp. 25-32
    • Simons, S.S.1    Miller, P.A.2
  • 93
    • 0032580484 scopus 로고    scopus 로고
    • Early pregnancy termination with mifepristone and misoprostol in the United States
    • Spitz, I.M., Bardin, C.W., Benton, L. and Robbins, A. (1998) Early pregnancy termination with mifepristone and misoprostol in the United States, N. Engl. J. Med. 338, 1241-1247.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1241-1247
    • Spitz, I.M.1    Bardin, C.W.2    Benton, L.3    Robbins, A.4
  • 94
    • 0028347608 scopus 로고
    • Dexamethasone down-regulates endothelin receptors in human cerebromicrovascular endothelial cells
    • Stanimirovic, D.B., McCarron, R.M. and Spatz, M. (1994) Dexamethasone down-regulates endothelin receptors in human cerebromicrovascular endothelial cells, Neuropeptides 26, 145-152.
    • (1994) Neuropeptides , vol.26 , pp. 145-152
    • Stanimirovic, D.B.1    McCarron, R.M.2    Spatz, M.3
  • 95
  • 96
    • 0032568527 scopus 로고    scopus 로고
    • Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains
    • Tanenbaum, D.M., Wang, Y., Williams, S.P. and Sigler, P.B. (1998) Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains, Proc. Natl Acad. Sci. USA 95, 5998-6003.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5998-6003
    • Tanenbaum, D.M.1    Wang, Y.2    Williams, S.P.3    Sigler, P.B.4
  • 99
    • 0036805791 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress
    • Tsigos, C. and Chrousos, G.P. (2002) Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress, J. Psychosom. Res. 53, 865-871.
    • (2002) J. Psychosom. Res. , vol.53 , pp. 865-871
    • Tsigos, C.1    Chrousos, G.P.2
  • 100
    • 0026019646 scopus 로고
    • Rapid reversal of acute psychosis in the Gushing syndrome with the cortisol-receptor antagonist Mifepristone (RU486)
    • Van der Lely, A.J., Foeken, K., Van der Mast, R.C. and Lamberts, S.W.J. (1991) Rapid reversal of acute psychosis in the Gushing syndrome with the cortisol-receptor antagonist Mifepristone (RU486), Ann. Int. Med. 114, 143-144.
    • (1991) Ann. Int. Med. , vol.114 , pp. 143-144
    • Van Der Lely, A.J.1    Foeken, K.2    Van Der Mast, R.C.3    Lamberts, S.W.J.4
  • 101
    • 0032575057 scopus 로고    scopus 로고
    • Atomic structure of progesterone complexed with its receptor
    • Williams, S.P. and Sigler, P.B. (1998) Atomic structure of progesterone complexed with its receptor, Nature 393, 392-396.
    • (1998) Nature , vol.393 , pp. 392-396
    • Williams, S.P.1    Sigler, P.B.2
  • 102
    • 0026541103 scopus 로고
    • Steroid inhibition of neural microvessel morphogenesis in vitro, receptor mediation and astroglial dependence
    • Wolff, J.E., Laterra, J. and Goldstein, G.W. (1992) Steroid inhibition of neural microvessel morphogenesis in vitro, receptor mediation and astroglial dependence, J. Neurochem. 58, 1023-1032.
    • (1992) J. Neurochem. , vol.58 , pp. 1023-1032
    • Wolff, J.E.1    Laterra, J.2    Goldstein, G.W.3


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