Immunohistochemical co-localization of lymphatics and blood vessels in oral squamous cell carcinomas

Journal of Oral Pathology and Medicine

Volumn 34, Issue 6, 2005, Pages 334-339

  Xuan, Ming ^a,b   Fang, Yi Ru ^b   Wato, Masahiro ^b   Hata, Shintaro ^b   Tanaka, Akio ^b  

^a SICHUAN UNIVERSITY   (China)

^b OSAKA DENTAL UNIVERSITY   (Japan)

Author keywords

Blood vessels; Double immunostaining; Lymphatics; Oral squamous cell carcinoma

Indexed keywords

CD34 ANTIGEN; MONOCLONAL ANTIBODY;

ADULT; AGED; ANGIOGENESIS; ARTICLE; BLOOD VESSEL; CLINICAL ARTICLE; FEMALE; HEMANGIOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHATIC SYSTEM; MALE; MOUTH CARCINOMA; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

3,3'-DIAMINOBENZIDINE; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; ANTIGENS, CD34; BLOOD VESSELS; CARCINOMA, SQUAMOUS CELL; COLORING AGENTS; FEMALE; HEMANGIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; LYMPHANGIOMA; LYMPHATIC VESSELS; MALE; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; NITROBLUE TETRAZOLIUM; TUMOR MARKERS, BIOLOGICAL;

EID: 20944442693     PISSN: 09042512     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2005.00316.x     Document Type: Article

References (22)

1. Kaipainen A, Korhonen J, Mustonen T, et al. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA 1995; 92: 3566-70.
2. Breiteneder-Geleff S, Soleiman A, Kowalski H, et al. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am J Pathol 1999; 154: 385-94.
3. Banerji S, Ni J, Wang SX, et al. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol 1999; 144: 789-801.
4. Wigle JT, Oliver G. Proxl function is required for the development of the murine lymphatic system. Cell 1999; 98: 769-78.
5. Stacker SA, Caesar C, Baldwin ME, et al. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med 2001; 7: 186-91.
6. Pepper MS. Lymphangiogenesis and tumor metastasis: myth or reality? din Cancer Res 2001; 7: 462-8.
7. Kahn HJ, Marks A. A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest 2002; 82: 1255-7.
8. Pindborg JJ, Reichert PA, Smith CJ, van der Waal I. WHO histological typing of tumor and precancer of the Oral Mucosa. Berlin: Springer-Verlag 1997; 11-3.
9. Kato S, Itonaga I, Ji RC, Miura M. Enzyme triple staining for differentiation of lymphatics from venous and arterial capillaries. Lymphology 1996; 29: 15-9.
10. Kitakaze M, Minamino T, Node K, et al. Role of activation of ectosolic 5′-nucleotidase in the cardioprotection mediated by opening of K + c channels. Am J Physiol 1996; 270: H1744-56.
11. Partanen TA, Arola J, Saaristo A, et al. VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J 2000; 14: 2087-96.
12. Valtola R, Salven P, Heikkila P, et al. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer. Am J Pathol 1999; 154: 1381-90.
13. Breiteneder-Geleff S, Matsui K, Soleiman A, et al. Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis. Am J Pathol 1997; 151: 1141-52.
14. Jussila L, Alitalo K. Vascular growth factors and lymphangiogenesis. Physiol Rev 2002; 82: 673-700.
15. Carreira CM, Nasser SM, di Tomaso E, et al. LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res 2001; 61: 8079-84.
16. Kahn HJ, Bailey D, Marks A. Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas. Mod Pathol 2002; 15: 434-40.
17. Erovic BM, Neuchrist C, Kandutsch S, Woegerbauer M, Pammer J. CD9 expression on lymphatic vessels in head and neck mucosa. Mod Pathol 2003; 16: 1028-34.
18. Jeltsch M, Kaipainen A, Joukov V, et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 1997; 276: 1423-5.
19. Oh SJ, Jeltsch MM, Birkenhager R, et al. VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Dev Biol 1997; 188: 96-109.
20. Karpanen T, Egeblad M, Karkkainen MJ, et al. Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 2001; 61: 1786-90.
21. Beasley NJ, Prevo R, Banerji S, et al. Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer. Cancer Res 2002; 62: 1315-20.
22. Mandriota SJ, Jussila L, Jeltsch M, et al. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J 2001; 20: 672-82.