Design, synthesis and structure-activity relationships of 6-O-arylpropargyl diazalides with potent activity against multidrug-resistant Streptococcus pneumoniae

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 10, 2005, Pages 2653-2658

  Yong, Hong ^a   Yu, Gui Gu ^a   Clark, Richard F ^a   Marron, Thomas ^a   Ma, Zhenkun ^a   Soni, Niru ^a   Stone, Gregory G ^a   Nilius, Angela M ^a   Marsh, Kennan ^a   Djuric, Stevan W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Ketolide; Macrolide

Indexed keywords

ANTIINFECTIVE AGENT; CETHROMYCIN; KETOLIDE; MACROLIDE; TE 802; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ACTIVITY RELATION;

STREPTOCOCCUS PNEUMONIAE;

EID: 20944439654     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.011     Document Type: Article

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