Enhancement of antitumor immune response in glioma models in mice by genetically modified dendritic cells pulsed with Semliki Forest virus-mediated complementary DNA

Journal of Neurosurgery

Volumn 94, Issue 3, 2001, Pages 474-481

  Yamanaka, R ^a   Zullo, S A ^a   Tanaka, R ^a   Blaese, M ^a   Xanthopoulos, K G ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

Antigen; Apoptosis; Dendritic cell; Gene therapy; Glioma; Mouse; Semliki Forest virus

Indexed keywords

CANCER VACCINE; COMPLEMENTARY DNA; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER IMMUNOTHERAPY; CELL ISOLATION; DENDRITIC CELL; DNA MODIFICATION; GENE THERAPY; GLIOMA; IMMUNE RESPONSE; MICROPHOTOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEMLIKI FOREST ALPHAVIRUS; SURVIVAL;

EID: 0034859436     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.2001.94.3.0474     Document Type: Article

References (23)

1. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
2. Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors
3. Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo
4. Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
5. Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: Biological efficacy study
6. Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses
7. Eradication of established intracranial rat gliomas by transforming growth factor β antisense gene therapy
8. Promoter for Sindbis virus RNA-dependent subgenomic RNA transcription
9. Alphavirus-induced apoptosis in mouse brains correlates with neurovirulence
10. Treatment of intracranial gliomas with bone marrow-derived dendritic cells pulsed with tumor antigens
11. Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour antiturnour immunity
12. The basic science of gene therapy
13. Bone marrow-derived dendritic cells pulsed with a tumor-specific peptide elicit effective anti-tumor immunity against intracranial neoplasms
14. Recombinant Sindbis virus as an expression system for cell biology
15. Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes
16. Adenovirusmediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo
17. Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system
18. The dendritic cell system and its role in immunogenicity
19. Dendritic cells in the T-cell areas of lymphoid organs
20. The alphaviruses: Gene expression, replication, and evolution
21. Suppression of TGF-beta1 in human gliomas by retroviral gene transfection enhances susceptibility to LAK cells
22. Cancer therapy using a selfreplicating RNA vaccine
23. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines