Mechanistic diversity of the van Leusen reaction applied to 6-ketomorphinans and synthetic potential of the resulting acrylonitrile substructures

Journal of Organic Chemistry

Volumn 70, Issue 13, 2005, Pages 5323-5326

  Schütz, Johannes ^a   Windisch, Petra ^a   Kristeva, Elka ^a   Wurst, Klaus ^a   Ongania, Karl Hans ^a   Horvath, Ulrike E I ^a   Schottenberger, Herwig ^a   Laus, Gerhard ^a   Schmidhammer, Helmut ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CRYSTAL STRUCTURE; NITROGEN COMPOUNDS; SODIUM COMPOUNDS; X RAY ANALYSIS;

7,8-DIDEHYDRO-6-KETOMORPHINANS; ACRYLONITRILE; GRIGNARD REAGENTS; VAN LEUSEN REACTIONS;

KETONES;

4 CINNAMYLOXY 5,6 DIDEHYDRO 14 BETA HYDROXY 3 METHOXY 17 METHYL 7 BETA (DIISOPROPYLAMINO) MORPHINAN 6 CARBONITRILE; 5,6,7,8 TETRADEHYDRO 3,4,14 BETA TRIMETHOXY 17 METHYLMORPHINAN 6 CARBONITRILE; 6 MORPHINANONE; 6,7 DIDEHYDRO 4,5 ALPHA EPOXY 14 BETA HYDROXY 3 METHOXY 17 METHYLMORPHINAN 6 CARBONITRILE; 7 ALPHA BENZYL 5,6 DIDEHYDRO 4,14 BETA DIHYDROXY 3 METHOXY 17 METHYLMORPHINAN 6 CARBONITRILE; 7 BETA BENZYL 5,6 DIDEHYDRO 4,14 BETA DIHYDROXY 3 METHOXY 17 METHYLMORPHINAN 6 CARBONITRILE; ACRYLONITRILE; MORPHINAN DERIVATIVE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; CYANATION; GRIGNARD REACTION; HYDROLYSIS; OXIDATION; STEREOCHEMISTRY; SYNTHESIS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; MOLECULAR STRUCTURE; MORPHINANS; NITRILES;

EID: 20844452725     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo050362v     Document Type: Article

References (12)

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